Bilateral Hilar Adenopathy: Causes & Reasons

Possible Causes for Bilateral Hilar Adenopathy

Loefgren’s syndrome, a specific variant of sarcoidosis, describes the triad of bilateral hilar adenopathy, erythema nodosum, and polyarthralgia or polyarthritis. [rheumaknowledgy.com]

(in Europe), mycoplasma, chlamydia, histoplasmosis, coccidioidomycosis, mycobacteria Sarcoidosis (11 to 25 percent) with bilateral hilar adenopathy Drugs (3 to 10 percent) [aafp.org]

At diagnosis 16.88 % of patients had a normal chest x-ray, 35.3 % presented with bilateral hilar adenopathy, 32.4 % were at stage II and 15.3 % at stage III. mode of onset [ftrdergisi.com]

Sarcoidosis

hilar adenopathy Dry cough Dyspnoe A combination of the first four symptoms is often described as Löfgren syndrome. [flexikon.doccheck.com]

Twenty-two patients admitted over a 2-year period to our department with bilateral hilar adenopathy and a variety of symptoms compatible with sarcoidosis were studied prospectively [ncbi.nlm.nih.gov]

hilar adenopathy in a patient with sarcoidosis. [smartypance.com]

Pulmonary Sarcoidosis

hilar adenopathy, fever, erythema nodosum and arthralgia · Intrathoracic disease (90%) · Adenopathy alone (43%)-Stage 1 · Intrathoracic adenopathy in 80% · Location · Bilateral [learningradiology.com]

The earliest is bilateral hilar adenopathy, which may be accompanied by right, left or bilateral paratracheal adenopathy. [jpgmonline.com]

 Löfgren's syndrome, an acute presentation of sarcoidosis, consists of arthritis, erythema nodosum, bilateral hilar adenopathy. 3.  Two third of patients have a remission [slideshare.net]

Pulmonary Cavitary Tuberculosis

Chest x-ray showing bilateral hilar adenopathy of primary pulmonary TB 6. [en.wikipedia.org]

[…] or mediastinal adenopathy at any age should strongly suggest TB Lymph node § Mostly unilateral hilar and/or paratracheal, usually right sided, rarely bilateral § Differentiates [learningradiology.com]

Bilateral adenopathy occurs in 31% cases. [17] The prevalence of adenopathy decreases with age. [17] CT is better than CXR in detection and characterization of thoracic LN [ijri.org]

Acute Berylliosis

CXR: - Stage 0 Clear - Stage I Bilateral hilar adenopathy - Stage II Hilar adenopathy and parenchymal infiltrates - Stage III Parenchymal infiltrates only - State IV Extensive [lumen.luc.edu]

Hilar adenopathy, noted in 30% to 40% of patients, is usually mild, bilateral, and associated with parenchymal infiltrates. [nap.edu]

Chest radiograph findings may include diffuse infiltrates and hilar adenopathy, but can be negative. Infiltrates may be granular, diffuse linear, or small nodules. [nap.edu]

Berylliosis

We report a case of a woman with a history of beryllium exposure who developed cough and progressive dyspnea, accompanied by bilateral hilar adenopathy and nodular parenchymal [nature.com]

Subsequent to steroid therapy, a marked decrease in pulmonary gallium uptake activity was noted with only residual hilar and mediastinal adenopathy noted. [ncbi.nlm.nih.gov]

hilar adenopathy and diffuse nodular pulmonary parenchymal disease on chest radiographs. [nature.com]

Pulmonary Tularemia

Frank lobar pneumonia may also develop, and bilateral hilar adenopathy may be present. [emedicine.medscape.com]

Pulmonary Lymphoma

adenopathy is usually bilateral but asymmetric Anterior mediastinal nodes commonly involved They may calcify after radiation therapy Staging (Ann Arbor) Stage I is adenopathy [learningradiology.com]

CT can reveal hilar and mediastinal adenopathies 9, 24. [erj.ersjournals.com]

[…] infiltrates (30%) Homogeneous confluent infiltrates with shaggy borders Contain air bronchogram Nodular form Multiple nodules Extraparenchymal manifestations in the chest Hilar [learningradiology.com]

Hodgkin Lymphoma

Pneumoconiosis

Radiographs revealed multiple bilateral pulmonary nodules associated with hilar and mediastinal adenopathy. [ncbi.nlm.nih.gov]

Pulmonary Tuberculosis

[…] more than lower § Alveolar infiltrate § Cavitation is rare § Lobar pneumonia is almost always associated with lymphadenopathy—therefore, lobar pneumonia associated with hilar [learningradiology.com]

Lymphoma

CT can reveal hilar and mediastinal adenopathies 9, 24. [erj.ersjournals.com]

A hilar adenopathy is observed in 70. Bronchial endoscopy is always normal and the diagnosis is almost always based on thoracotomy findings 70. [erj.ersjournals.com]

Less than 10% of patients have bilateral diffuse reticulonodular opacities, atelectasia or pleural effusion [13, 14, 24]. [erj.ersjournals.com]

Pulmonary Fungal Infection

• Massive inhalation of organisms: – May show fairly discrete, nodular opacities 3-4 mm in diameter with hilar adenopathy 11. [slideshare.net]

Fig. acute histoplasmosis widespread bilateral well-defined 3-5 mm nodules 12. [slideshare.net]

Histoplasmosis

No hilar adenopathy or pleural effusion is present. Reprinted from Arch Pediatr Adolesc Med 1994;148:833-4 Copyright (1994). American Medical Association. [clinicaladvisor.com]

There is a bilateral, diffuse, miliary, pulmonary parenchymal pattern of densities with greater involvement of the lower lobes. [clinicaladvisor.com]

Coccidioidomycosis

[…] lung involvement prominent hilar adenopathy CF antibody test titers of equal to or greater than 1:16 inability to work due to symptoms symptoms persist for 12 months patient [ncbi.nlm.nih.gov]

He also had diffuse, bilateral pneumonia with hilar adenopathy and a papular eruption on his chest; skin biopsies showed superficial perivascular inflammation without identifiable [journals.lww.com]

[…] patient are as follows: weight loss of 10% or more intense night sweats persisting symptoms longer than three weeks infiltrates involving more than one-half of one lung or bilateral [ncbi.nlm.nih.gov]

Infectious Mononucleosis

Characterized by the classic triad of fever, pharyngitis, and lymphadenopathy, along with atypical lymphocytosis. Often subclinical in young children. Positive heterophile antibody test and serologic test for antibodies against EBV are usually diagnostic. Rare but potentially life-threatening complications include severe[…] [us.bestpractice.bmj.com]

Small-Cell Carcinoma of the Lung

Metastasis from small-cell carcinoma of the lung (SCCL) has most frequently been found in the lymph nodes, bones, brain, and liver. We have reported a case of metastatic SCCL located in the uveal layer of both eyes (choroidal in one and iridic in the other), an extremely rare occurrence. [ncbi.nlm.nih.gov]

Bronchogenic Carcinoma

We report a case of localized fibrous mesothelioma (LFM) of the pleura with bronchogenic carcinoma. LFM arose in the visceral pleura of the upper lobe in the left lung, and lung adenocarcinoma was located in the ipsilateral lower lobe. LFM is a rare mesenchymal tumor of the pleura. Concomitant occurrence with[…] [ncbi.nlm.nih.gov]

Recurrent Small-Cell Carcinoma of the Lung

There is no standard therapy for relapsed small cell lung cancer (rSCLC). We evaluated the efficacy and toxicity of a new triplet consisting of irinotecan (100 mg/m(2) Days 1 and 15 q28), cisplatin (40 mg/m(2) Days 1 and 15 q28) and mitomycin (6 mg/m(2) d1 q28) administered to a maximum of 6 cycles in individuals[…] [ncbi.nlm.nih.gov]

Transient Sarcoidosis

Löfgren's syndrome (especially in Caucasians): erythema nodosum, fever, arthralgias, and radiographic evidence of bilateral hilar adenopathy - likely Sarcoidosis (ref Parrish [medicine.uiowa.edu]

Stage II: bilateral hilar lymphadenopathy with pulmonary infiltrates. Stage III: pulmonary infiltrates without hilar adenopathy. [slideshare.net]

Figure 13-2 illustrates the chest roentgenogram from a sarcoidosis patient with bilateral hilar adenopathy. [what-when-how.com]

Cystic Fibrosis

Genetic multisystem disease associated with abnormalities in salt and water transport across epithelial surfaces. Age of onset of symptoms is highly variable; implementation of newborn screening in some countries allows for early detection and treatment. A sweat test is the most conclusive test for diagnosis.[…] [bestpractice.bmj.com]

Mediastinal Neoplasm

Background Several tumors of neurogenic origin can occur in the mediastinum. Tumors that occur in this area of the chest can present in many different ways clinically and can produce many different pathologic processes. An understanding of the embryology of this area and of the anatomic relationships of the[…] [emedicine.medscape.com]

Acute Sarcoidosis

Stages of sarcoidosis, as identified through imaging, are as follows (see also the images below): Stage O - No findings Stage I - Bilateral hilar adenopathy Stage II - Bilateral [emedicine.medscape.com]

hilar adenopathy and parenchymal involvement (reticular opacities) Stage III - Parenchymal involvement (reticular opacities) with shrinking adenopathy Stage IV - Parenchymal [emedicine.medscape.com]

hilar or paratracheal adenopathy and joint involvement (EN is associated with a good prognosis) Subcutaneous nodules Ocular lesions Ocular involvement is the presenting symptom [emedicine.medscape.com]

Amyloidosis

7 April, 2020 at 10:43 PM For the rest of spring semester and all summer sessions, Boston University has directed undergraduate students to return home, canceled in-person classes, moved to remote teaching, called off all events and athletics, and minimized lab research. Visit our COVID-19 website for further[…] [bu.edu]

Viral Pneumonia

Clin Chest Med. 2017 Mar;38(1):155-169. doi: 10.1016/j.ccm.2016.11.009. Epub 2016 Dec 18. Author information 1 Respiratory Sciences, National Heart and Lung Institute, Imperial College London (St Mary's Campus), Norfolk Place, Paddington, London W2 1PG, UK. 2 Respiratory Sciences, National Heart and Lung Institute, Imperial[…] [ncbi.nlm.nih.gov]

Systemic Amyloidosis

Clin Nucl Med. 2015 Feb;40(2):189-90. doi: 10.1097/RLU.0000000000000593. Author information 1 From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India. Abstract Amyloidosis is a rare disorder characterized by variable extracellular accumulation of a complex substance consisting of[…] [ncbi.nlm.nih.gov]

Gastrointestinal Sarcoidosis

hilar adenopathy stage 2 bilateral hilar adenopathy with parenchymal infiltrates stage 3 diffuse parenchymal infiltrates in the absence of hilar adenopathy stage 4 pulmonary [step2.medbullets.com]

Classically used for staging that has therapeutic and prognostic implication: Stage I – bilateral hilar adenopathy Stage II – bilateral hilar adenopathy and pulmonary infiltrates [cancertherapyadvisor.com]

A chest radiograph is obtained, which demonstrate bilateral hilar adenopathy without any appreciable pulmonary parenchymal infiltrates. [step2.medbullets.com]

Superior Vena Cava Syndrome

The approach to an intrinsic cause of superior vena cava syndrome (SVCS) is usually difficult but rewarding. We report a case of a middle-aged man who presented with progressive oedema of the upper half of the body, dyspnoea, cough and weight loss for a 1-year duration. He was a non-smoker without prior[…] [ncbi.nlm.nih.gov]

Silicosis

Silicosis Definition Silicosis is a progressive disease that belongs to a group of lung disorders called pneumoconioses. Silicosis is marked by the formation of lumps (nodules) and fibrous scar tissue in the lungs. It is the oldest known occupational lung disease, and is caused by exposure to inhaled particles of silica,[…] [medical-dictionary.thefreedictionary.com]

Brucellosis

Brucellosis Other names undulant fever, undulating fever, Mediterranean fever, Malta fever, Cyprus fever, rock fever (Micrococcus Melitensis)[1] Specialty Infectious disease Symptoms coughing Brucellosis[2][3] is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected[…] [en.wikipedia.org]