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305 Possible Causes for Bilateral Leg Weakness

  • Spinal Trauma

    Although Harvey Cushing played a central role in the establishment of neurosurgery in the United States, his work on the spine remains largely unknown. This article is not only the first time that Cushing's spinal cases while he was at Johns Hopkins have been reported, but also the first time his management of[…][]

  • Multifocal Motor Neuropathy

    Abstract Multifocal motor neuropathy (MMN) is a progressive disorder producing asymmetrical weakness and muscle wasting. Case reports suggest that patients with MMN improve after cyclophosphamide therapy, but not after prednisone or plasmapheresis. Because MMN is likely to be immune mediated, we investigated the[…][]

  • Bilateral Leg Weakness

    Rarely, cervical cord tumors can initially cause bilateral leg weakness without involvement.[] And this is where bilateral leg weakness -- described here as something that "may be caused by a malfunction of the brain, the spinal cord, or nerves" -- becomes a bilateral[] A 35-year-old woman presented with one month's history of progressive bilateral leg weakness and altered sensation. There had been no pain.[]

  • Spinal Cord Compression

    Leg pain may occur and be unilateral or bilateral in nature that radiates from the back.[] Motor Weakness: This usually follows pain, the time frame for this sign is often variable, from hours to days, weeks or months.[]

  • Spinal Epidural Abscess

    The esophageal stent is used extensively for a malignant stricture, and many complications have been reported. We present a case of esophageal cancer with surgical esophageal stenting. Spinal epidural abscess occurred postoperatively, and we believe that the pathogenesis may be related to the esophageal stent.[]

  • Glycogen Storage Disease Type 2

    Pompe disease is an inherited disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally. Researchers have described three types of Pompe disease, which differ in[…][]

  • Hereditary ATTR Amyloidosis

    What is TTR-FAP and who gets it? Approximately 10,000, or 1.1 per 100,000 people in the world, are estimated to be living with TTR-FAP, which often shows up when patients are in their thirties or forties. TTR-CM tends to affect older males, ie., men who are 65 or older. However, many cases of both forms of the[…][]

  • Amyotrophic Lateral Sclerosis 3

    Amyotrophic lateral sclerosis (ALS) is a progressive and generally fatal motor neuron disease. Most cases are sporadic, but high familial incidence is observed occasionally. Amyotrophic lateral sclerosis 3 (ALS3) is one of many subtypes of familial ALS. It has been related to chromosomal locus 18q21 and is inherited in[…][]

  • Amyotrophic Lateral Sclerosis 6

    J Biomol Struct Dyn. 2015;33(4):834-44. doi: 10.1080/07391102.2014.915762. Epub 2014 May 14. Author information 1 a School of Bio Sciences and Technology (SBST), Bioinformatics Division , Vellore Institute of Technology University , Vellore 632014 , Tamil Nadu , India. Abstract Amyotrophic lateral sclerosis 6 (ALS6) is an[…][]

  • Vitamin B12 Deficiency

    She presented with memory loss and progressive leg weakness. Her legs were hypotonic with decreased power, absent reflexes and bilateral extensor plantar reflexes.[]

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