Bilateral Leg Weakness: Causes & Reasons

Possible Causes for Bilateral Leg Weakness

Leg pain may occur and be unilateral or bilateral in nature that radiates from the back. [healthengine.com.au]

Motor Weakness: This usually follows pain, the time frame for this sign is often variable, from hours to days, weeks or months. [healthengine.com.au]

Hereditary ATTR Amyloidosis

He had severe polyneuropathy and bilateral weakness and had experienced episodes of syncope. [frontiersin.org]

He also had a history of paresthesia, orthostatic hypotension, numbness (starting with his left leg, spreading upwards), difficulty walking, orthostatic loss of consciousness [frontiersin.org]

Lambert-Eaton Syndrome

Examination revealed mild bilateral ptosis, a prominent waddling gait, proximal weakness that was worse in the legs, and barely elicitable reflexes. [docksci.com]

Spinal Trauma

Traumatic spinal cord injury can manifest as a wide variety of clinical syndromes resulting from damage to the spinal cord or its surrounding structures. It can result from minor injury if the spine is weakened from disease such as ankylosing spondylitis or if there is pre-existing spinal stenosis. It is an emergency[…] [radiopaedia.org]

Postural Orthostatic Tachycardia Syndrome

Overview Tae Chung of the Johns Hopkins Rehabilitation Network discusses postural orthostatic tachycardia syndrome (POTS) - a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. To refer a patient to Dr. Chung for POTS, please[…] [clinicalconnection.hopkinsmedicine.org]

Multifocal Motor Neuropathy

Multifocal motor neuropathy (MMN) and anti-myelin-associated glycoprotein (anti-MAG)-associated neuropathy are clinically and electrophysiologically distinct entities. We describe a patient with characteristic features of both neuropathies, raising the possibility of an overlap syndrome. A 49-year-old patient reported[…] [ncbi.nlm.nih.gov]

Bilateral Leg Weakness

Rarely, cervical cord tumors can initially cause bilateral leg weakness without involvement. [sites.google.com]

And this is where bilateral leg weakness -- described here as something that "may be caused by a malfunction of the brain, the spinal cord, or nerves" -- becomes a bilateral [startribune.com]

A 35-year-old woman presented with one month's history of progressive bilateral leg weakness and altered sensation. There had been no pain. [ncbi.nlm.nih.gov]

Spinal Epidural Abscess

Pyogenic spinal epidural abscess Is an uncommon Infectious occurrence. Clinical prospects of pyogenic spinal epidural abscess are graver if not promptly diagnosed and treated appropriately. A case of spinal epidural abscess has been presented with sinus tract formation at L4-L5 level, of pyogenic aetiology that[…] [ncbi.nlm.nih.gov]

Pompe Disease

Pompe disease is an inherited disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally. Researchers have described three types of Pompe disease, which differ in[…] [ghr.nlm.nih.gov]

Idiopathic Inflammatory Myopathy

OBJECTIVE: To examine the role of HLA-DRB1 and tumor necrosis factor (TNF) promoter genotypes in the development and the autoantibody profiles of idiopathic inflammatory myopathy (IIM) in Japanese patients. METHODS: HLA-DRB1 and TNF promoter genotypes were determined, and serum antinuclear autoantibodies were[…] [ncbi.nlm.nih.gov]

Amyotrophic Lateral Sclerosis Type 6

Amyotrophic lateral sclerosis (ALS) is a progressive and generally fatal motor neuron disease. Most cases are sporadic, but high familial incidence is observed occasionally. Amyotrophic lateral sclerosis 6 (ALS6) is one of many subtypes of familial ALS. It has been related to mutations in the FUS gene, a protein-coding[…] [symptoma.com]

Amyotrophic Lateral Sclerosis Type 3

ALS3 An approved symbol from the HUGO Gene Nomenclature Committee (HGNC) database for a gene on chromosome 18q21. Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved. References in periodicals archive ? Neuromuscular disorders such as ALS3 and Parkinson's accounted for the second largest[…] [medical-dictionary.thefreedictionary.com]

Autosomal Recessive Spastic Paraplegia Type 63

leg spasticity and weakness. [journals.lww.com]

Spastic paraplegia 7 (SPG7) is characterized by insidiously progressive bilateral leg weakness and spasticity. [ncbi.nlm.nih.gov]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Malignant Neoplasm of Head and Neck

A 63-year-old man presented with acute back pain and bilateral leg weakness 5 months after having a surgical treatment for moderately differentiated vocal cord squamous cell [ncbi.nlm.nih.gov]

Anterior Spinal Artery Syndrome

[…] anterior spinal artery---> affects the anterior horn cells and pain and temperature pathways - bilateral leg weakness - areflexia /flaccid paralysis - loss of bowel and bladder [aippg.net]

weakness. [oatext.com]

The following illustrates such a case: A 40 year old theatre nurse who recently had a long-haul flight woke up at 2 am complaining of back pain, chest pain and bilateral leg [oatext.com]

Paraparesis

PARAPARESIS Paraparesis refers to bilateral leg weakness. [pediatricneuro.com]

leg weakness Applies To Paralysis of both lower limbs Paraplegia (lower) ICD-9-CM Volume 2 Index entries containing back-references to 344.1 : [icd9data.com]

On examination, she was found to have severe spasticity and weakness of both legs and feet, bilateral Babinski sign, and bilateral patellar clonus (see video ). [nejm.org]

Autosomal Recessive Spastic Paraplegia Type 21

leg spasticity and weakness. [journals.lww.com]

Spastic paraplegia 7 (SPG7) is characterized by insidiously progressive bilateral leg weakness and spasticity. [ncbi.nlm.nih.gov]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Parasagittal Meningioma

Features include: seizures or pyramidal weakness in the leg which may progress to bilateral leg weakness if the lesion extends through the falx homonymous hemianopias from [gpnotebook.co.uk]

Large parasagittal meningiomas may result in bilateral leg weakness. [brighamandwomens.org]

Large parasagittal meningiomas may present with bilateral leg weakness. [medpagetoday.com]

Cauda Equina Syndrome

Cauda Equina Syndrome Clinical Evaluation Severe bilateral leg pain, weakness, saddle anesthesia (perianal numbness), bowel/bladder symptoms (urninary retention early, urine [eorif.com]

Patients may present with back pain, unilateral or bilateral leg pain, paresthesias and weakness, perineum or saddle anesthesia, and rectal and/or urinary incontinence or [doi.org]

[increased tone in both legs, bilateral weakness in flexors, brisk reflexes and upgoing plantars] Cauda equina will typically cause lower motor neurone weakness [flaccid [oxfordmedicaleducation.com]

Hereditary Proximal Myopathy with Early Respiratory Failure

Neurologic exam revealed thinning of the anterior legs, bilateral calf hypertrophy, neck flexor and extensor weakness, distal greater than proximal weakness in the legs, and [neurology.org]

[…] progressed to prominent distal weakness and respiratory insufficiency (FVC of 29%). [neurology.org]

Design/Methods: Case report Results: A 29-year-old Afghan woman with no family history of muscle disease who developed proximal limbgirdle weakness in her early 20s that slowly [neurology.org]

Cauda Equina Injury

Also, there may be decreased anal tone; sexual dysfunction; saddle anesthesia; bilateral leg pain and weakness; and bilateral absence of ankle reflexes. [urmc.rochester.edu]

leg pain and/or weakness common Change in sensation in the lower extremities Bladder dysfunction (retention and/or incontinence) – up to 92% (Korse 2017) Disruption of autonomic [rebelem.com]

Autosomal Recessive Spastic Paraplegia Type 44

leg spasticity and weakness. [journals.lww.com]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Olfactory Groove Meningioma

Large parasagittal meningiomas may result in bilateral leg weakness. [brighamandwomens.org]

Large parasagittal meningiomas may present with bilateral leg weakness. [medpagetoday.com]

Autosomal Recessive Spastic Paraplegia Type 46

leg spasticity and weakness. [journals.lww.com]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 61

leg spasticity and weakness. [journals.lww.com]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 25

leg spasticity and weakness. [journals.lww.com]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]

Autosomal Recessive Spastic Paraplegia Type 39

leg spasticity and weakness. [journals.lww.com]

Neurological examination disclosed mild spasticity and weakness in the legs, hyperreflexia in all limbs, and bilateral Babinski sign. [bmcmedgenet.biomedcentral.com]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Upper Limb Hypertrophy

[…] as late effects of cerebrovascular accident Weakness of arm Weakness of bilat arms Weakness of bilat legs Weakness of bilateral legs Weakness of both arms Weakness of extremities [icd9data.com]

Patient’s face showed gross lipodystropy, wasting of sternmastoid muscles and upper arms muscles, bilaterally ( figure 4A-4D ). [omicsonline.org]

[…] examination - sign - lower limb Paresis of lower extremity (finding) Paresis, leg Peripheral muscle fatigue Rheumatic fever nodule Swelling of buttock Upper limb tension Weakness [icd9data.com]

Paraplegia

leg weakness Applies To Paralysis of both lower limbs Paraplegia (lower) ICD-9-CM Volume 2 Index entries containing back-references to 344.1 : [icd9data.com]

leg weakness. [sideeffects.embl.de]

[…] most often associated with spinal cord diseases, although brain diseases; peripheral nervous system diseases; neuromuscular diseases; and muscular diseases may also cause bilateral [icd9data.com]

Autosomal Dominant Spastic Paraplegia Type 36

leg spasticity and weakness. [journals.lww.com]

More than 50% of affected individuals have some weakness in the legs and an impaired sense of vibration at the ankles. [centogene.com]

Moderate truncal ataxia was present with bilateral dysmetria and dysdiadochokinesia. It was not possible to assess cerebellar function in the legs due to weakness. [journals.plos.org]