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180 Possible Causes for Bilateral Leg Weakness, Cardiac Arrhythmia

  • Hereditary ATTR Amyloidosis

    […] disorders (e.g. arrhythmias, cardiac failure), ocular disorders (e.g. macular degeneration), alcoholism, and vitamin B12 deficiency.[ncbi.nlm.nih.gov] Table 2 Treatment for clinical symptoms of transthyretin familial polyneuropathy (TTR-FAP) Arrhythmias Pacemaker implantation, pharmacotherapy Cardiac failure Diuretics, angiotensin[ojrd.biomedcentral.com] In the heart conduction problems (blocks) are frequently the first manifestation of cardiac involvement, but also cardiac failure (often right sided) can be seen.[amyloid.nl]

  • Carnitine Deficiency

    We describe a case of a 35-year-old woman who presented with bilateral leg weakness and encephalopathy while on long-term valproate therapy.[ncbi.nlm.nih.gov] Lethal cardiac arrhythmia was documented in five patients, while one patient was not monitored at time of death, but had signs of cardiac arrhythmia a few days earlier.[ncbi.nlm.nih.gov] Short QT syndrome is associated with an increased risk of cardiac arrhythmias and unexpected sudden death.[ncbi.nlm.nih.gov]

  • Weaver Syndrome

    Bilateral hind leg weakness and ataxia appear in afflicted animals at 6 to 18 months of age, and slowly progresses to total loss of hind limb control by 3 to 4 years of age[ncbi.nlm.nih.gov] Moreover, prolonged cardiovascular collapse and cardiac arrhythmias may occur.[ncbi.nlm.nih.gov] The antihistamine fexofenadine does not affect IKr currents in a case report of drug-induced cardiac arrhythmia Scherer CR, Lerche C, Dennis AT, Maier P, Ficker E, Pinto YM[humangenetik-umg.de]

  • Drop Attacks

    A single embolus may lodge in this common vessel which then results in bilateral leg weakness.[brainscape.com] Cardiac arrhythmia with decreased cerebral perfusion ,uswer 3-15: E. Cardiac arrhythmia is most likely to produce presyncopal sensations.[brainscape.com] Bilateral leg weakness can result if both arteries have a common origin, an anomaly in about 20% of individuals Questions 3.12 : Orthostatic hypotension is rarely a cause[brainscape.com]

  • Lyme Neuroborreliosis

    leg weakness, urinary retention, and sensory abnormalities, can mimic such diseases as Guillain-Barré, multiple sclerosis, and acute disseminated encephalomyelitis and lead[hosppeds.aappublications.org] : myopericarditis, cardiac arrhythmia musculoskeletal: Lyme arthritis Treatment and prognosis Treatment is based with antibiotics depending on the stage of the disease and[radiopaedia.org] […] include transverse myelitis, plexopathies, mononeuropathy multiplex, and complex mononeuropathy multiplex. 8 , 11 These syndromes, which can have such varying presentations as bilateral[hosppeds.aappublications.org]

  • Multifocal Motor Neuropathy

    A sizeable number of patients also develop autonomic dysfunction where they experience fluctuations in their blood pressure and cardiac arrhythmias.[hopkinsmedicine.org]

  • Rhabdomyolysis

    , bilateral leg pain, and recurrent falls.[ncbi.nlm.nih.gov] arrhythmias, acute renal failure ( 30%) and tetanus.[radiopaedia.org] arrhythmias secondary to ion changes.[scielo.br]

  • Adrenal Insufficiency

    A 65-year-old male with liver cirrhosis of alcoholic etiology was admitted to hospital with bilateral leg edema, ascites, and marked weakness.[ncbi.nlm.nih.gov] Death is a common outcome, usually from hypotension or cardiac arrhythmia secondary to hyperkalemia, unless replacement steroid therapy is begun.[emedicine.medscape.com]

  • Miller-Fisher Syndrome

    Urinary Retention Hx of rapidly progressive bilateral leg weakness e.g. after a diarrhoea illness 3-4 weeks before Examn: - Lower limb LMN signs Hyporeflexia Flaccid paralysis[brainscape.com] […] signs of respiratory failure or cardiac arrhythmias.[cancertherapyadvisor.com] Cardiac arrhythmia. Ileus. Aspiration pneumonia . Urinary retention . Psychiatric problems - eg, depression , anxiety .[patient.info]

  • Glycogen Storage Disease Type 2

    Dearmey, “Cardiac Arrhythmias Following Anesthesia Induction in Infantile-Onset Pompe Disease: A Case Series,” Pediatric Anesthesia, Vol. 17, No. 8, 2007, pp. 738-748. doi[scirp.org] ., Cardiac arrhythmias following anesthesia induction in infantile-onset Pompe disease: a case series.[rarediseases.org] Ventricular hypertrophy is a frequent finding, but overt cardiac dysfunction is rare. 22 – 25 Sudden death thought to be caused by cardiac arrhythmias has been reported. 23[nature.com]

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