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96 Possible Causes for Bilateral Leg Weakness, Cardiomyopathy, Numbness of the Hand

  • Hereditary ATTR Amyloidosis

    Familial amyloid cardiomyopathy (FAC) is also known as hereditary cardiac TTR amyloidosis or hereditary amyloid cardiomyopathy.[] It can cause loss of sensation, tingling, numbness or pain in the hands and feet (also known as peripheral neuropathy).[] […] and feet (peripheral neuropathy) nausea, diarrhoea or constipation numbness, tingling and pain in the wrist, hand and fingers (carpal tunnel syndrome) an enlarged tongue[]

  • Transient Ischemic Attack

    Motor function Unilateral or bilateral weakness affecting the face, arm, or leg Bilateral signs may indicate more ominous onset of brainstem ischemia.[] […] artery disease Circulation problems, especially poor blood circulation in the legs Diabetes Family history of stroke Heart disease, including heart valve disease and dilated cardiomyopathy[] However, the symptoms may also be subtle, such as numbness or burning of a limb, or clumsiness with the use of hand or while walking .[]

  • Thyrotoxic Periodic Paralysis

    […] kidney stones status post lithotripsy presented with worsening bilateral leg cramping and generalized weakness of 2 days duration.[] Flecainide has been shown to be successful in treating bidirectional ventricular tachycardia, ventricular ectopy, and tachycardia-induced cardiomyopathy. [20][] We herein report a 25-yr-old Korean man who suffered from flaccid paralysis of the lower extremities and numbness of hands.[]

  • Hereditary Spastic Paraplegia

    Major symptoms comprise progressive bilateral leg stiffness, spasticity at rest and diffuse muscle weakness.[] […] containing protein 3A) were recently found to cause a neurological syndrome with developmental delay, hypotonia, spasticity, optic atrophy, axonal neuropathy, and hypertrophic cardiomyopathy[] […] in hands or feet) and deafness.[]

  • Cryoglobulinemia

    We describe a case of a 79-year-old woman with a non-cirrhotic hepatitis C virus infection presenting with weakness, arthralgias, purpuric rash with left leg ulcerative lesions[] Heart involvement is rare, with the main manifestation being myocardial ischemia and dilated cardiomyopathy. 29 In a cohort of 209 patients with cryoglobulinemia, 14% had[] […] turn white, then blue, and then red from constriction and subsequent dilation of the blood vessels), or numbness in the hands and feet.[]

  • Cervical Myelopathy

    Abstract A 70-year-old African American woman presented to the pain management clinic with complaints of lower back pain and bilateral calf pain with weakness in her legs.[] […] autosomal recessive genetic disorder with multisystemic involvement characterised by early blindness, hearing loss, obesity, insulin resistance, diabetes mellitus, dilated cardiomyopathy[] Symptoms Hand numbness, tingling and "electrical shocks" are often early symptoms of cervical myelopathy. This numbness typically affects the whole hand.[]

  • Arteriovenous Fistula

    A 14-year-old girl presented with a 3-week history of slowly progressive unilateral leg weakness that quickly progressed to bilateral leg paralysis, sphincter dysfunction,[] […] embolic microspheres in the form of particles to treat hemorrhages, arteriovenous malformations, hemangioendothelioma, cerebral aneurysms, muscle hypertrophy, hypertrophic cardiomyopathy[] Risks and possible complications include: The fistula not working properly Long wait before the fistula is ready (up to 6 months) Coldness or numbness in the hand (due to[]

  • Guillain-Barré Syndrome

    leg weakness, ascending sensory) Vasculitic neuropathies (mononeuropathy) Characteristic CSF findings consist of elevated protein (higher than 0.55 g per dL [5.5 g per L][] Takotsubo cardiomyopathy is a rare complication in Guillain-Barré syndrome; eight other cases have been reported in the literature.[] This starts with mild symptoms, such as numbness in the hands and feet. It then spreads up the limbs and progresses to severe weakness and paralysis.[]

  • Bilateral Leg Weakness

    Rarely, cervical cord tumors can initially cause bilateral leg weakness without involvement.[] […] data Type II fiber atrophy; lymphocytic vasculitis; myositis Genetic Becker muscular dystrophy Hip; proximal leg and arm Late childhood to adulthood Mental retardation; cardiomyopathy[] See What Causes Hand Pain and Numbness?[]

  • Paraplegia

    leg weakness.[] .  Hypertrophic cardiomyopathy with progression to intractable CHF is the cause of death.  visual evoked response, BERA and somatosensory evoked potentials are abnormal.[] […] or loss of sensation in the hands and fingers Paraplegia Treatment Damage to the spinal cord cannot be reversed.[]

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