Bilateral Proptosis: Causes & Reasons

Possible Causes for Bilateral Proptosis

cavernous sinus thrombosis, or leukemic infiltrates can also produce bilateral proptosis. [aao.org]

CLASSIFICATION Proptosis can be divided into following clinical groups: Unilateral proptosis Bilateral proptosis Acute proptosis Intermittent proptosis Pulsating proptosis [ikeyes.blogspot.com]

Etiology / Causes of Proptosis: Inflammatory/Infection: Graves’ ophthalmopathy, due to Graves’ disease (Thyroid Eye Disease), usually causes bilateral proptosis. [oculoplastic-eyelid-orbit-surgery.com]

Exophthalmos

She had bilateral proptosis with Hertel's exophthalmometry readings of 26 mm (right) and 27 mm (left) ( Figure 1 ). Visual acuity was 20/60 bilaterally. [ncbi.nlm.nih.gov]

She had bilateral proptosis with Hertel’s exophthalmometry readings of 26 mm (right) and 27 mm (left) (Figure 1). Visual acuity was bilaterally. [hindawi.com]

A 52-year-old Chinese woman with progressively worsening bilateral proptosis presented to our hospital. [ncbi.nlm.nih.gov]

Graves Disease

At presentation, he was noted to have bilateral proptosis. [ncbi.nlm.nih.gov]

Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic [ncbi.nlm.nih.gov]

An exam is notable for mild bilateral proptosis, thin hair, and moist skin. A goiter is visible; it has increased consistency on palpation with an audible bruit over it. [the-hospitalist.org]

Langerhans-Cell Histiocytosis

Orbital psuedotumor represents the second most common inflammatory disorder of the orbit in childhood and may present with unilateral or bilateral proptosis of explosive onset [eyewiki.aao.org]

[…] antigen presenting function of the dendritic cells would remain unknown for more than a century. [13] Differential diagnosis Orbital cellulitis is the most common cause of proptosis [eyewiki.aao.org]

Melkersson-Rosenthal Syndrome

Fundus retinal exam, optic nerves and slit lamp exams were normal bilaterally. [healio.com]

intraocular pressures of 21 mm Hg in each eye, normal color vision, and no proptosis by Hertel measurements. [healio.com]

[…] visual acuity of 20/60 OD and 20/20 left eye (OS), mild metamorphopsia by Amsler grid testing, equal pupils with no afferent pupillary defect, full extraocular movement bilaterally [healio.com]

Pilocytic Astrocytoma

The baby developed irritability and fussiness with marked proptosis of the left globe following surgery. The radiotherapy was felt to yield relief to the symptoms. [nature.com]

The patient who received radiation alone was a 10-month-old neurofibromatosis type 1 baby boy with an optic nerve pilocytic astrocytoma involving the bilateral optic nerves [nature.com]

Rhinocerebral Mucormycosis

It demonstrated marked right proptosis, thickening of the extraocular muscles, opacification of right maxillary, ethmoid and sphenoid sinuses, bilateral opacification of mastoid [hindawi.com]

Granulomatosis with Polyangiitis

Granulomatosis with polyangiitis Other names Wegener's granulomatosis (WG) Micrograph showing features characteristic of granulomatosis with polyangiitis – a vasculitis and granulomas with multi-nucleated giant cells. H&E stain. Specialty Immunology, Rheumatology Granulomatosis with polyangiitis (GPA), previously known as[…] [en.wikipedia.org]

Superior Vena Cava Syndrome

The approach to an intrinsic cause of superior vena cava syndrome (SVCS) is usually difficult but rewarding. We report a case of a middle-aged man who presented with progressive oedema of the upper half of the body, dyspnoea, cough and weight loss for a 1-year duration. He was a non-smoker without prior[…] [ncbi.nlm.nih.gov]

Phencyclidine Intoxication

Rhabdomyolysis can occur with phencyclidine hydrochloride (PCP) intoxication. However, to our knowledge acute renal failure with phencyclidine-induced rhabdomyolysis has not been reported previously. Therefore, we describe two patients with this condition. The modern treatment of phencyclidine intoxication, namely[…] [ncbi.nlm.nih.gov]

Orbital Lymphoma

The most frequent cause of bilateral proptosis is Graves' ophthalmopathy, and when it is associated with weight loss in an elderly patient, the initial diagnostic consideration [ncbi.nlm.nih.gov]

Signs and symptoms of Graves' ophthalmopathy, such as unilateral or bilateral proptosis, double vision, limitation of movement of the extraocular muscles, are not specific [ncbi.nlm.nih.gov]

Physical examination ( Fig. 1, upper panel ) showed marked, bilateral proptosis, soft tissue inflammation, and mild impairment of ocular movement ( 1 ). [academic.oup.com]

Pulsating Exophthalmos

Another tumour affecting the orbit and so resulting in proptosis is granulocytic sarcoma (chloroma) which may present with rapid onset of (occasionally bilateral) proptosis [patient.info]

proptosis were the subjects for the study. [ijri.org]

Subperiosteal Hemorrhage

What is the differential diagnosis of severe proptosis in a neonate? Bilateral neonatal proptosis is rare. [bjo.bmj.com]

He had bilateral proptosis worse on the right with severe conjunctival chemosis, bilateral lid oedema and right pan-ophthalmitis [Figure 1]. [nigerianjournalofophthalmology.com]

Examination revealed mild nonpulsatile proptosis of the left eye with mild medial gaze restriction. Bilateral ocular fundus examination were normal. [neurologyindia.com]

Orbital Disease

A 53-year-old male visited Severance Hospital for evaluation of bilateral proptosis and periorbital eyelid swelling for 3 months. [synapse.koreamed.org]

Graves orbitopathy is the most common cause of unilateral and bilateral proptosis. [emedicine.medscape.com]

Proptosis• Abnormal protrusion of globe• It may be Unilateral or Bilateral• Unilateral – caused by orbital cellulitis, idiopathic orbital inflammatory disease, thrombosis [slideshare.net]

Periocular Meningioma

Typically, TED presents with bilateral proptosis, diplopia, conjunctival injection and eyelid retraction. [reviewofoptometry.com]

[…] only after an infectious entity and other inflammatory systemic conditions are ruled out.2 Thyroid eye disease (TED) should also be considered in patients who present with proptosis [reviewofoptometry.com]

Crouzon Syndrome

Bilateral proptosis with large degree of exotropia left eye was seen in primary gaze. [casereports.bmj.com]

CT Scan revealed bilateral, lateral and third ventricular dilatation, proptosis and dolicocephalic skull. The fourth ventricle was normal. [indianpediatrics.net]

There was bilateral proptosis [Figure 1]. [mjdrdypu.org]

Orbital Infection

Cavernous sinus thrombosis is characterized by bilateral photophobia, proptosis, ophthalmoplegia, hypoesthesia of the cornea. [symptoma.com]

Indications for a CT to rule-out orbital cellulitis include: o Inability to accurately assess vision o Gross proptosis, ophthalmoplegia, bilateral edema, or deteriorating [errolozdalga.com]

Cavernous sinus thrombosis: causes bilateral symptoms, including proptosis, eye pain, sensory deficits affecting the cornea, and bilateral orbital apex syndrome. B. [clinicaladvisor.com]

Orbital Pseudotumor

A 39-year-old woman developed bilateral proptosis, photophobia, and pain with extraocular movements over the course of 5 days. [ncbi.nlm.nih.gov]

A 39-year-old man had bilateral proptosis and blurred vision for I week. [ncbi.nlm.nih.gov]

Computed tomography (CT) scan of the orbit showed bilateral proptosis (29 mm from orbital margin, Figures 2 and 3) with bilateral symmetric hypertrophy of all extraocular [ncbi.nlm.nih.gov]

Chronic Thyroiditis

Examination revealed bilateral conjunctival injection, bilateral proptosis. There was no extraoccular muscle weakness, restriction in movement of eyeball or any bruit. [casereports.in]

Case 4 A 57-year-old woman presented with a 3-month history of bilateral proptosis and diplopia. [dovepress.com]

Case 2 – A 28-year-old female referred to our clinic with bilateral proptosis and parotid swelling from three months ago. [archivesofrheumatology.org]

Cushing Syndrome due to Macronodular Adrenal Hyperplasia

A 52-year-old Chinese woman with progressively worsening bilateral proptosis presented to our hospital. [ncbi.nlm.nih.gov]

Subsequently she was diagnosed as having primary bilateral macronodular adrenal hyperplasia and underwent bilateral laparoscopic adrenalectomy. [ncbi.nlm.nih.gov]

Raine Syndrome

proptosis with chemosis and bilateral corneal opacities, low set ears, midfacial hypoplasia, hypoplastic nose with bilateral choanal atresia, micrognathia/retrognathia. [slideplayer.com]

Other findings included bilateral severe proptosis with optic atrophy, everted lower eyelids, severely hypoplastic nose with choanal atresia, depressed nasal bridge, and mid-face [cags.org.ae]

Her weight was 2200g, length 45cm, and head circumference 31cm with wide bulging anterior fontanel, bilateral severe proptosis, severely hypoplastic nose with choanal atresia [latunisiemedicale.com]

Ghose-Sachdev-Kumar Syndrome

proptosis as a rare manifestation of neurocysticercosis ... p. 210 Akhilesh K Singh, Prabhat K Agrwal, Juned Ahmad, Ashish Gautam DOI:10.4103/0975-2870.153165 COMMENTARY [mjdrdypu.org]

[…] imaging in Mayer-Rokitansky-Kuster-Hauser syndrome ... p. 206 Sanjay M Khaladkar, Rajesh Kuber, Dhaval K Thakkar, Anubhav Kamal, VM Kulkarni DOI:10.4103/0975-2870.153164 Bilateral [mjdrdypu.org]

Enchondromatosis

We treated a 34-year-old man with Maffucci's syndrome, bilateral proptosis secondary to multiple intraorbital hemangiomas, corneal exposure secondary to a left facial nerve [miami.pure.elsevier.com]

Bupropion Poisoning

Proptosis, European Journal of Case Reports in Internal Medicine: Vol. 5 No. 11 Miguel Trindade, Joana Carvalho, Mariana Barosa, João Serôdio, Ricardo Oliveira, Ana Furtado [ejcrim.com]

European Journal of Case Reports in Internal Medicine: Vol. 5 No. 1 Joao Fernandes Serodio, Marta Jonet, Miguel Trindade, Inês Coutinho, Catarina Favas, A Rare Case of Bilateral [ejcrim.com]

Launois Syndrome

Launois-Bensaude syndrome was diagnosed in a 70-year-old-man who presented with severe bilateral proptosis (Hertel value 26mm). [ncbi.nlm.nih.gov]

Proptosis reduction was 7mm. Postoperative Hertel values were 19mm in both eyes. The proptosis was managed successfully. [ncbi.nlm.nih.gov]

We performed a bilateral transpalpebral orbital decompression by resection of intraorbital fat without bone removal. The surgery was uneventful. [ncbi.nlm.nih.gov]

Dural Carotid Cavernous Fistula

Axial T1 MRI demonstrating left-sided proptosis and bilateral SOV enlargement Disease Entity A carotid-cavernous fistula (CCF) is the result of an abnormal vascular connection [eyewiki.aao.org]

Ophthalmic signs that can be seen in both direct and indirect CCFs include proptosis, eyelid edema, ptosis, conjunctival arterialization, elevated intraocular pressure, pulsatile [eyewiki.aao.org]

[…] can also have pulsatile tinnitus as a result of turbulent flow through the venous system (Figure 3).[23] Symptoms are typically ipsilateral to the fistula but can occur bilaterally [eyewiki.aao.org]

Cavernous Sinus Thrombosis

Seven days later, however, he presented to the emergency department with a worsening headache, progressive altered mental status, fever, and bilateral proptosis. [journals.lww.com]

Later, ophthalmoplegia (typically the 6th cranial nerve in the initial stage), proptosis, and eyelid edema develop and often become bilateral. [merckmanuals.com]

proptosis with periorbital soft tissue swelling. [journals.lww.com]

Nodular Nonsuppurative Panniculitis

[…] n L 2015 9 Fat-Removal Orbital Decompressing for Severe Bilateral Proptosis due to Weber-Christian Disease. ( 25978784 ) Cizmeci O...Ceran F 2015 10 Skin lesions depicting [malacards.org]

Proptosis due to Weber-Christian Disease. 61 Cizmeci O...Ceran F 25978784 2015 12 Weber-Christian disease with ileocolonic involvement successfully treated with infliximab [malacards.org]

10 Nephrotic syndrome in a patient with Pfeifer-Weber-Christian disease. 61 Riveros Frutos A...Mateo Soria L 25543272 2015 11 Fat-Removal Orbital Decompressing for Severe Bilateral [malacards.org]

Fibrosclerosis of the Breast

proptosis and blurred vision for I week. [collections.lib.utah.edu]

proptosis in adults. [meajo.org]

Computed tomography and magnetic resonance imaging showed signs of bilateral orbital pseudotumor, a suprasellar mass, and pulmonary infiltration. [collections.lib.utah.edu]

IgG4-Related Ophthalmic Disease

proptosis with frozen globe (complete restriction of ocular movements) in a middle aged female with IgG4-related orbitopathy Click here to view Figure 2: Computed tomography [meajo.org]

Dacryoadenitis typically led to proptosis. Most patients (71%) had bilateral ophthalmic disease as well as extra-orbital involvement. [acrabstracts.org]

[…] periorbital and/or eyelid swelling, erythema, and proptosis. [eyewiki.aao.org]