[…] enzyme in bile acid synthesis, to increase the conversion of hepatic cholesterol to bile acids. 2 It has not yet been approved for use in the UK.
Role of bile acids and metabolic activity of colonic bacteria in increased risk. Dig Dis Sci. 38, 514-519. Lorenzo-Z??iga, V, Bartol?, R, and Planas, R (2003).
Some experts believe that it results from an increase in bile, especially bile acids, entering the large intestine — which may act as a laxative.