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340 Possible Causes for Bilirubin Increased, Easy Bruising, Fatigue

  • Primary Biliary Cirrhosis

    Patients may have a low platelet count because of an enlarged spleen causing easy bruising.[medicinenet.com] Among patients with early disease, bilirubin increased to 2 mg/dL in the anti-NPC( ) patients (26% vs. 5%, P .019).[ncbi.nlm.nih.gov] This Review article discusses the natural history and the measurement of fatigue in patients with PBC.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Symptoms Symptoms may include: Abdominal pain Back pain Blood clots , may form in some people Dark urine, comes and goes Easy bruising or bleeding Headache Shortness of breath[mountsinai.org] […] in total bilirubin concentrations (median 3.4 mg/dL; range 2.1-8.1 mg/dL) during chronic eculizumab treatment and normal/or slightly increased serum aminotransferase activities[ncbi.nlm.nih.gov] By using the Functional Assessment of Chronic Illness Therapy Fatigue instrument (scores can range from 0 to 52, with higher scores indicating improvement in fatigue), the[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    Most common in chronic myelogenous leukemia and agnogenic myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to[emedicine.com] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 30, 2019[patientslikeme.com]

  • Polycythemia Vera

    Individuals, who demonstrate signs and symptoms, have the following: Trouble breathing, feeling weak and tired Easy bruising and bleeding Severe, throbbing headache Skin appears[dovemed.com] Regardless of baseline iron status, treatment with ruxolitinib was associated with improvements in concentration problems, cognitive function, dizziness, fatigue, headaches[ncbi.nlm.nih.gov] […] bleeding/bruising 4.[slideshare.net]

  • Acute Leukemia

    Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the[nlm.nih.gov] ), abdominal pain and high levels of bilirubin in the blood (hyperbilirubinemia).[fda.gov] The initial manifestations of leukemia are generally signs of bone marrow failure, such as pallor, fatigue, fever, bleeding, and infection related to peripheral blood cytopenias[ncbi.nlm.nih.gov]

  • Acute Lymphoblastic Leukemia

    Symptoms of ALL include: Weakness or feeling tired Fever Easy bruising or bleeding Bleeding under the skin Shortness of breath Weight loss or loss of appetite Pain in the[nlm.nih.gov] Abstract We present the case of a 16-year-old boy who presented with fatigue, polyuria, and polydipsia while on chemotherapy for his relapsed acute lymphoblastic leukemia[ncbi.nlm.nih.gov] ), abdominal pain and high levels of bilirubin in the blood (hyperbilirubinemia).[fda.gov]

  • Chronic Myeloid Leukemia

    It can lead to easy bruising or bleeding, with frequent or severe nosebleeds and bleeding gums. Some patients with CML actually have too many platelets (thrombocytosis).[cancer.org] The most common adverse effects during the study were thrombocytopenia (20% -33%), neutropenia (13% -31%), elevated bilirubin (7%), and increased serum lipase (5% -15%).[intechopen.com] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com]

  • Leukemia

    Easy bruising or bleeding: People with leukemia may bleed from their gums or noses, or may find blood in their stool or urine. Bruises may develop from very minor bumps.[my.clevelandclinic.org] ), abdominal pain and high levels of bilirubin in the blood (hyperbilirubinemia).[fda.gov] Evidence-based treatment for cancer-related fatigue . J Natl Cancer Inst Monogr. 2004 ;32: 112 - 118 .[doi.org]

  • Chronic Myelomonocytic Leukemia

    A shortage of blood platelets (thrombocytopenia) can lead to easy bruising and bleeding. Some people notice frequent or severe nosebleeds or bleeding from their gums.[cancer.org] bilirubin, and so on.[ncbi.nlm.nih.gov] Dose-limiting toxicities (DLTs) consisted of grade 3 fatigue, grade 3 typhilitis, grade 3 syncope and grade 3 QTc prolongation).[ncbi.nlm.nih.gov]

  • Vitamin B12 Deficiency

    The symptoms of B12 deficiency include tiredness, light-headedness , rapid heart rate , easy bruising and bleeding, weight loss, bowel upset and sore tongue.[healthdirect.gov.au] The clinical symptoms are weakness, fatigue, shortness of breath and neurologic abnormalities.[ncbi.nlm.nih.gov] While skin paleness shows that there’s a drop in the levels of functional RBCs, the yellowness can be attributed to the increased levels of bilirubin – which is the same compound[curejoy.com]

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