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689 Possible Causes for Bilirubin Increased, Easy Bruising, Fatigue, Tinnitus

  • Myeloproliferative Disease

    Most common in chronic myelogenous leukemia and agnogenic myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to[emedicine.com] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 30, 2019[patientslikeme.com] Splenomegaly, hepatomegaly as well as fatigue, malaise or weight loss may appear in advanced stages.[orpha.net] The resulting fibrous scar tissue formation leads to severe anemia, weakness, fatigue and an enlarged spleen and liver.[llscanada.org]

  • Polycythemia Vera

    Individuals, who demonstrate signs and symptoms, have the following: Trouble breathing, feeling weak and tired Easy bruising and bleeding Severe, throbbing headache Skin appears[dovemed.com] 79.5%) patients experienced momelotinib-related adverse events (AEs), the most frequent being headache (23.1%), dizziness (18.0%), somnolence (15.4%), nausea (15.4%), and fatigue[ncbi.nlm.nih.gov] Polycythemia Vera Signs and symptoms Symptoms related to expanded blood volume and increased viscosity Headache, tinnitus, dizziness, blurred vision, TIAs, and fatigue Generalized[slideshare.net] Regardless of baseline iron status, treatment with ruxolitinib was associated with improvements in concentration problems, cognitive function, dizziness, fatigue, headaches[ncbi.nlm.nih.gov]

  • Vitamin B12 Deficiency

    The symptoms of B12 deficiency include tiredness, light-headedness , rapid heart rate , easy bruising and bleeding, weight loss, bowel upset and sore tongue.[healthdirect.gov.au] The clinical symptoms are weakness, fatigue, shortness of breath and neurologic abnormalities.[ncbi.nlm.nih.gov] […] lethargy) breathlessness feeling faint headaches pale skin noticeable heartbeats (palpitations) hearing sounds coming from inside the body, rather than from an outside source ( tinnitus[nhs.uk] While skin paleness shows that there’s a drop in the levels of functional RBCs, the yellowness can be attributed to the increased levels of bilirubin – which is the same compound[curejoy.com]

  • Acute Myelocytic Leukemia

    Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[medlineplus.gov] Symptoms include anemia, fatigue, weight loss, easy bruising, thrombocytopenia, and granulocytopenia that leads to persistent bacterial infections.[medical-dictionary.thefreedictionary.com] […] in a previously normal serum aminotransferase or alkaline phosphatase level or a total bilirubin level exceeding 3.0 mg per deciliter (51.3 μmol per liter).[doi.org] Symptoms include: Unexplained and persistent fever Marked fatigue and weakness Unexpected weight loss with poor appetite Easy bruising or bleeding.[drugs.com]

  • Anemia

    bruising Milky nipple discharge (called galactorrhea ) Early puberty (mostly seen in children with severe, longstanding disease) Delayed puberty (often the first obvious[verywell.com] The most common symptoms of anemia are fatigue and an inability to focus. Gradually, one’s performance begins to decline and judgments become impaired.[the.ismaili] Tinnitus This is extremely common in patients with PA and is probably due to slight nerve damage to the brain.[pernicious-anaemia-society.org] […] acid dehydrogenase (LDH), indirect bilirubin, hepatosplenomegaly and a low haptoglobin (reflecting clearance of haptoglobin/plasma hemoglobin complexes).[cancertherapyadvisor.com]

  • Aplastic Anemia

    Symptoms include: Bleeding gums Easy bruising Nose bleeds Rash, small pinpoint red marks on the skin (petechiae) Frequent or severe infections (less common) Mild cases of[nlm.nih.gov] Fatigue is the most common presentation as it is the first symptom of low red blood cell count. Fatigue also sets in when there is a lack of hemoglobin in the blood.[symptoma.com] Other symptoms may include a waxy pallor to the skin and mucous membranes, bleeding gums, a lack of energy during exercise, and tinnitus (ringing in the ears).[medbroadcast.com] Low platelet counts can result in easy bruising or bleeding. Some people with aplastic anemia show no symptoms at all.[froedtert.com]

    Missing: Bilirubin Increased
  • Primary Biliary Cirrhosis

    Patients may have a low platelet count because of an enlarged spleen causing easy bruising.[medicinenet.com] This Review article discusses the natural history and the measurement of fatigue in patients with PBC.[ncbi.nlm.nih.gov] Among patients with early disease, bilirubin increased to 2 mg/dL in the anti-NPC( ) patients (26% vs. 5 %, P .019).[ncbi.nlm.nih.gov] Among patients with early disease, bilirubin increased to 2 mg/dL in the anti‐NPC( ) patients (26% vs. 5%, P .019).[dx.doi.org]

    Missing: Tinnitus
  • Paroxysmal Nocturnal Hemoglobinuria

    Symptoms Symptoms may include: Abdominal pain Back pain Blood clots, may form in some people Dark urine, comes and goes Easy bruising or bleeding Headache Shortness of breath[mountsinai.org] By using the Functional Assessment of Chronic Illness Therapy Fatigue instrument (scores can range from 0 to 52, with higher scores indicating improvement in fatigue), the[ncbi.nlm.nih.gov] […] in total bilirubin concentrations (median 3.4 mg/dL; range 2.1-8.1 mg/dL) during chronic eculizumab treatment and normal/or slightly increased serum aminotransferase activities[ncbi.nlm.nih.gov] Symptoms Symptoms may include: Abdominal pain Back pain Blood clots , may form in some people Dark urine, comes and goes Easy bruising or bleeding Headache Shortness of breath[huronregional.org]

    Missing: Tinnitus
  • Severe Aplastic Anemia

    These include fatigue, shortness of breath, fever, recurrent infections, easy bruising or unusual bleeding.[leukemiabmtprogram.org] Patients typically have fatigue, infections, and increased or unusual bleeding. A bone marrow biopsy establishes the diagnosis.[ncbi.nlm.nih.gov] Other symptoms may include a waxy pallor to the skin and mucous membranes, bleeding gums, a lack of energy during exercise, and tinnitus (ringing in the ears).[chealth.canoe.com] Platelets are responsible for normal blood clotting and low numbers can result in easy bruising and bleeding which can be deadly.[clinicaltrials.gov]

    Missing: Bilirubin Increased
  • Chronic Myeloid Leukemia

    It can lead to easy bruising or bleeding, with frequent or severe nosebleeds and bleeding gums. Some patients with CML actually have too many platelets (thrombocytosis).[cancer.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] The objective was to describe a unique case of sudden bilateral hearing loss, tinnitus, and vertigo presenting as the first symptoms of chronic myeloid leukemia (CML).[ncbi.nlm.nih.gov] The most common adverse effects during the study were thrombocytopenia (20% -33%), neutropenia (13% -31%), elevated bilirubin (7%), and increased serum lipase (5% -15%).[intechopen.com]

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