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61 Possible Causes for Bilirubin Increased due to Hemolysis

  • Paroxysmal Exertion-Induced Dyskinesia

    Paroxysmal exercise-induced dystonia (PED) is a rare, typically idiopathic familial condition, although sporadic and secondary cases have been reported. We present 2 cases where PED was the presenting feature of young-onset idiopathic Parkinson's disease (PD), preceding the onset of parkinsonian symptoms by 1.5[…][ncbi.nlm.nih.gov]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] Hematologic Studies A complete blood cell (CBC) count may reveal the following: Anemia due to microangiopathic hemolysis, hemoconcentration due to third spacing, or physiologic[emedicine.com]

  • Neonatal Hyperbilirubinemia

    In this issue of Clinics in Perinatology, we provide updates on the current understanding of the biology, mechanisms of increasing bilirubin load due to hemolysis, decreased[books.google.de] Physiologic jaundice occurs due to increased hematocrit, slow functioning of glucuronyl transferase, and increased enterohepatic circulation.[sharinginhealth.ca] Increased destruction of bilirubin, such as by hemolysis, hematoma, or other causes, will result in high levels of uncongugated bilirubin.[sharinginhealth.ca]

  • Hereditary Spherocytosis

    Furthermore, the fragile cell membrane causes the spherocyte to lyse due to increased cellular permeability, releasing hemoglobin.[symptoma.com] Increased hemolysis will lead to increased bilirubin, a breakdown product of heme, thus, hyperbilirubinemia, manifested by jaundice.[symptoma.com]

  • Physiological Neonatal Jaundice

    Physiologic jaundice occurs due to increased hematocrit, slow functioning of glucuronyl transferase, and increased enterohepatic circulation.[sharinginhealth.ca] Preterm new borns are prone to developing jaundice due to immaturity of bilirubin conjugating system, higher rate of hemolysis, increased enterohepatic circulation, decreased[medresearch.in] Increased destruction of bilirubin, such as by hemolysis, hematoma, or other causes, will result in high levels of uncongugated bilirubin.[sharinginhealth.ca]

  • Neonatal Jaundice

    Physiologic jaundice occurs due to increased hematocrit, slow functioning of glucuronyl transferase, and increased enterohepatic circulation.[sharinginhealth.ca] The most common causes of pathologic indirect hyperbilirubinemia are : 1) increased bilirubin production due to hemolytic disease process that includes the Immune mediated[ncbi.nlm.nih.gov] This substance may increase how much bilirubin the baby's body can reabsorb.[urmc.rochester.edu]

  • Mental Retardation

    Hyperbilirubinemia may result from increased destruction of red cells (eg, hemolysis due to maternal-child blood group incompatibility) or decreased excretion of bilirubin[emedicine.com]

  • Exchange Transfusion

    Due to tolerance of higher bilirubin levels in term infants without evidence of hemolysis 1 and improved obstetric management of Rh-sensitized mothers, the last 15 years have[pediatrics.aappublications.org] Improvements in outcome from advances in neonatal care may have been offset by the increased risk of adverse events attributable to inexperience with the procedure.[pediatrics.aappublications.org]

  • Acquired Hemolytic Anemia

    Jaundice may be present due to increase in indirect bilirubin in hemolysis. Some hemolytic anemias like hereditary spherocytosis can have splenomegaly.[medcaretips.com] In extreme hemolysis: free hemoglobin Brown-colored urine due to hemoglobinuria This test detects antibodies and/or complement proteins on RBCs surface ; (direct test) or[amboss.com] Patchy hyperpigmentation, sore tongue, and gastrointestinal symptoms may indicate folate deficiency which occur due to increased folate consumption.[medcaretips.com]

  • Bile Acid Synthesis Defect with Cholestasis and Malabsorption

    Physiologic jaundice, a temporary elevation of indirect bilirubin during the first few days of life, is due to increased bilirubin production, decreased ability to eliminate[clinicaladvisor.com] Unconjugated hyperbilirubinemia is an elevation of indirect bilirubin resulting from hemolysis, birth trauma, polycythemia, ileus, or hypothyroidism.[clinicaladvisor.com]

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