Initial symptoms include sudden onset of bifrontal or bitemporal headaches, high fever, nuchal rigidity, anorexia, vomiting, irritability and restlessness.
[cdipd.org]
Clinical Presentation in Humans (Ma et al., 1990) After the initial incubation period, N. fowleri infection is characterized by abrupt onset of bifrontal or bitemporal headache
[web.stanford.edu]