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55 Possible Causes for Blast Cells Present, Peripheral Blood Smear Abnormal

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Pediatric chronic myeloid leukemia with B - cell lymphoid blast crisis at presentation. Blood Res 2013;48:151 -2. 3. Calabretta B, Perrotti D.[ajmhs.org] The World Health Organization (WHO) has defined the criteria for each in accordance with the percentage of blast cells and other important values.[symptoma.com] The majority of patients are diagnosed in the chronic phase and may be either asymptomatic (diagnosed through a routine white blood cell count) or present with fatigue, anaemia[orpha.net]

  • Chronic Myelomonocytic Leukemia

    Peripheral blood smear for CMML showing abnormal cells. Chronic myelomonocytic leukemia (CMML) is an aggressive cancer of the blood that is resistant to treatment.[uofuhealth.utah.edu] Bone Marrow flow cytometry: 78% mature granulocytes, 2% lymphocytes, 10% monocytes, 7% erythroid precursors and 3% blasts. 1% CD19-positive B cells present, 1% CD3-positive[omicsgroup.org] In addition, morphologic evaluation of the peripheral blood smear and T-cell gene rearrangement studies by polymerase chain reaction (PCR) were performed.[ncbi.nlm.nih.gov]

  • Chronic Eosinophilic Leukemia

    The bone marrow exhibited 45% to 55% eosinophilic hyperplasia and 30% of myeloid blast cells (panel C; blue arrows show blast cells).[bloodjournal.org] Presently, an unexplained chronic persistent eosinophilia with a demonstrable cytogenetic abnormality or an increase in blast cells is considered as eosinophilic leukemia[article.sciencepublishinggroup.com] Red blood cells and platelets were normal and there were no circulating blast cells.[bloodjournal.org]

  • B-Precursor Acute Lymphoblastic Leukemia

    CD1d leukemic blasts were able to present alpha-GalCer via CD1d to cytotoxic CD1d-restricted T cells, which induced apoptosis of ALL cells that was inhibited by mAb to CD1d[ncbi.nlm.nih.gov] At diagnosis, there is essentially complete replacement of normal hematopoiesis with blast cells and there are no differentiating morphologic features between patients with[journals.plos.org] , LDH and uric acid were presented by mean SD.[omicsonline.org]

  • T-cell Acute Lymphoblastic Leukemia

    Clinically, T-ALL patients present with diffuse infiltration of the bone marrow by immature T-cell blasts high blood cell counts, mediastinal involvement, and diffusion to[ncbi.nlm.nih.gov] However, in contrast to previous reports in ALL or acute myeloid leukemia, our patient did not have blasts noted on periphereal blood smear and her white blood cell count[ncbi.nlm.nih.gov] WT1, ETV6, JAK1, JAK3, and RUNX1, were present, while CDKN2A/B deletions/mutations were never detected.[ncbi.nlm.nih.gov]

  • Thrombocytopenia

    Peripheral blood smear shows abnormal erythrocyte size and shape as well as paucity of platelets.[orpha.net] High white blood cell count or blasts may be present in acute or chronic leukemia. Step 2: Review peripheral smear.[antimicrobe.org] If an abnormally low platelet count is detected in the absence of a suggestive medical history, examination of a peripheral blood smear on a freshly taken specimen should[patient.info]

  • Refractory Anemia with Excess Blasts in Transformation

    Peripheral blood smear The peripheral blood frequently shows abnormal cytoplasmic granularity and nuclear segmentation of the neutrophils.[imagebank.hematology.org] The blast cell present in the BM are usually CD34 and express myeloid markers (i.e. CD33 and/or CD13).[atlasgeneticsoncology.org] Leukemia that is characterized by the presence of abnormal white blood cells in the peripheral blood but in which the total number of white blood cells is normal.[quizlet.com]

  • Refractory Anemia with Excess Blasts

    Peripheral blood smear The peripheral blood frequently shows abnormal cytoplasmic granularity and nuclear segmentation of the neutrophils.[imagebank.hematology.org] The blast cell present in the BM are usually CD34 and express myeloid markers (i.e. CD33 and/or CD13).[atlasgeneticsoncology.org] The peripheral blood smear can show macrocytosis of the red cells and hypo-granular neutrophils.[businessandleadership.com]

  • Refractory Anemia

    Peripheral blood smear The peripheral blood frequently shows abnormal cytoplasmic granularity and nuclear segmentation of the neutrophils.[imagebank.hematology.org] A valuable clue to the diagnosis of either β- or α-thalassemia minor can be the presence of moderate peripheral blood smear abnormalities despite an insignificant anemia ([aafp.org] (Outcomes/Resolutions) The severity of Refractory Anemia with Excess Blasts depends on the degree to which blast cell levels are elevated, and if Auer rods are present.[dovemed.com]

  • Acute Undifferentiated Leukemia

    A 42-year-old female patient with dyspnea on exertion and purpurae was evaluated at a local hospital and was detected to have pancytopenia Peripheral smear examination revealed[oatext.com] Thus, these two patients had acute erythroblastic leukemia which differs from erythroleukemia (M6 of FAB classification) in which blast cells present myeloblastic characteristics[ncbi.nlm.nih.gov] Blast count is 84%. Trilineage hematopoiesis is present but reduced, with only occasional megakaryocytes, red blood cell precursors, and neutrophils seen.[gpec.ubc.ca]

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