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36 Possible Causes for Bleeding Diathesis, Monocyte Count Increased, Thrombocytopenic Purpura

  • Immune Thrombocytopenic Purpura

    Immune thrombocytopenic purpura (ITP), also called primary immune thrombocytopenia or idiopathic thrombocytopenic purpura, is an autoimmune disease affecting thrombocytes.[] A year later she presented with bleeding diathesis and was diagnosed as ITP.[] ITP is a clinical syndrome in which a decreased number of platelets manifest as bleeding diathesis, easy bruising and capillary blood leakage into the mucus membranes and[]

  • Aplastic Anemia

    Acquired amegakaryocytic thrombocytopenic purpura (AATP) is a rare hematological disorder characterized by severe thrombocytopenia and a complete or near-to complete absence[] Although the GI bleed could be explained by portal hypertension and gastropathy, the epistaxis was likely due to a bleeding diathesis secondary to thrombocytopenia.[] FDA approves Promacta to treat pediatric patients with chronic immune thrombocytopenic purpura The U.S.[]

  • Acute Monocytic Leukemia

    At that point, one might see early recovery with increasing numbers of monocytes, mid-range myeloid cells, and a higher platelet count, even if some blasts are present in[] Purpura Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease Challenge Yourself Interactive Medical Cases Image Challenge Videos in Clinical Medicine View all[] For patients with APML, bleeding diathesis continues to be a major cause of early death and previously led to high rates of mortality in induction or prior to induction.[]

  • Acute Myelocytic Leukemia

    JMML characteristically presents with hepatosplenomegaly, lymphadenopathy, fever, and skin rash along with an elevated white blood cell (WBC) count and increased circulating[] [PUBMED Abstract] Ghauri RI, Naveed M, Mannan J: Congenital amegakaryocytic thrombocytopenic purpura (CAMT). J Coll Physicians Surg Pak 24 (4): 285-7, 2014.[] A general bleeding diathesis may be the result of thrombocytopenia. Patients may claim a propensity for epistaxis, bleeding gums, melena and hematochezia, and hematuria.[]

  • Myeloproliferative Disease

    Thrombotic thrombocytopenic purpura – This results in the reduction of platelet production and bleeding tendencies.[] Defects in glycoprotein (GP)IIb-IIIa or in its activation may cause abnormal platelet aggregation and a bleeding diathesis.[]

  • Gaucher Disease

    purpura (ITP) 2.Patients who were definitively diagnosed as aplastic anemia 3.[] Clinical manifestations include hepatosplenomegaly, thrombocytopenia, bone disease and a bleeding diathesis, frequently resulting in presentation to haematologists.[] [] Clinical manifestations include hepatosplenomegaly, thrombocytopenia, bone disease and a bleeding diathesis, frequently resulting in presentation to haematologists[]

  • Thrombocytopenia

    She had increased monocyte cell count (1.82   10/L), markedly decreased platelet count (2   10/L), hypercellularity of the megakaryocyte lineage with many immature megakaryocytes[] Abstract Thrombotic thrombocytopenic purpura (TTP) is an acute, life-threatening illness with disseminated platelet-rich thromboses of small vessels that variably presents[] Clinical diagnosis Bleeding diathesis probably related to low platelets.[]

  • Chronic Myelomonocytic Leukemia

    The Mayo prognostic model classified CMML patients into three risk groups based on: increased absolute monocyte count, presence of circulating blasts, hemoglobin 9 /L.[] A preliminary diagnosis of thrombotic thrombocytopenic purpura (TTP) was made on the basis of clinical presentation and lab findings, such as reduced platelet count, increased[] diathesis caused by lack of platelets.[]

  • Waldenstrom Macroglobulinemia

    This suggests that the mechanism of immune thrombocytopenia in our case is different from that of idiopathic thrombocytopenic purpura.[] Coagulation parameters may also be useful given the risk of a bleeding diathesis associated with high circulating levels of IgM. D. Long-term management.[] Thrombocytopenia is found in approximately 50% of patients with bleeding diathesis.[]

  • Multiple Myeloma

    purpura (Day 6/Cycle 2).[] Patients may present with symptoms due to profound anemia, hypercalcemia or bleeding diathesis owing to thrombocytopenia.[] diathesis (in some patients due to factor X deficiency; fig. 1 ).[]

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