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264 Possible Causes for Bleeding Diathesis, Petechiae, Thrombocytopenic Purpura

  • Immune Thrombocytopenic Purpura

    Immune thrombocytopenic purpura (ITP), also called primary immune thrombocytopenia or idiopathic thrombocytopenic purpura, is an autoimmune disease affecting thrombocytes.[symptoma.com] A year later she presented with bleeding diathesis and was diagnosed as ITP.[ncbi.nlm.nih.gov] Abstract In this retrospective cohort study conducted in 63 children with idiopathic thrombocytopenic purpura (ITP) in China; petechiae, bruises and bleeding were the major[ncbi.nlm.nih.gov]

  • Kasabach Merritt Syndrome

    purpura or hypersplenism.Placental chorioangiomas are the most widespread non-trophoblastic benign tumor-like lesions of placenta.[ncbi.nlm.nih.gov] A patient can lose up to 70% of their coagulation factors before developing a clinical bleeding diathesis, so the goal is the ensure the levels of coagulation factors remain[ispub.com] Kasabach-Merritt syndrome (KMS) consists of large and rapidly growing vascular tumors associated with thrombocytopenia, generalized petechiae, and bleeding.[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    We report on 3 male neonates with hereditary ADAMTS13 deficiency (Upshaw Schulman syndrome, USS), the inherited form of thrombotic thrombocytopenic purpura (TTP). 2 presented[ncbi.nlm.nih.gov] Bleeding diathesis must be corrected before surgery in order to prevent massive intraoperative bleeding.[kjim.org] Two weeks later, he was transferred to the West China Hospital with nasal hemorrhage for 1 week, hematochezia, hematuria, and petechiae for 5 days.[ncbi.nlm.nih.gov]

  • Glanzmann Thrombasthenia

    Acquired Glanzmann's thrombasthenia (GT) is an uncommon accompaniment to immune thrombocytopenic purpura.[ncbi.nlm.nih.gov] Patients with Glanzmann thrombasthenia experience lifelong spontaneous and post-traumatic mucocutaneous bleeding diathesis.[ncbi.nlm.nih.gov] The clinical history of Glanzmann thrombasthenia may include the following: Excessive bleeding after dental extraction (this may often be the first sign of the disease) Petechiae[emedicine.medscape.com]

  • Thrombocytopenia

    Abstract Thrombotic thrombocytopenic purpura (TTP) is an acute, life-threatening illness with disseminated platelet-rich thromboses of small vessels that variably presents[ncbi.nlm.nih.gov] Clinical diagnosis Bleeding diathesis probably related to low platelets.[wjgnet.com] Larger than petechiae, ecchymoses are purple, blue or yellow-green areas of skin that vary in size and shape.[en.wikipedia.org]

  • Bleeding Diathesis

    purpura.[ncbi.nlm.nih.gov] Bleeding diathesis is a term describing a propensity toward bleeding or hemorrhage, which can be a constitutive feature of numerous disorders of vascular, genetic, or autoimmune[symptoma.com] An accurate description of the several forms of cutaneous bleeding (petechiae, purpuric spots, ecchymosis, haematomas, etc.) is needed for referrals and for controls.[ncbi.nlm.nih.gov]

  • Thrombocytopathy

    Thrombocytopenic purpura thrombocytopenic purpura n. See idiopathic thrombocytopenic purpura.[definithing.com] Patients with thrombocytopathy due to storage pool disease mostly suffer from mild bleeding diathesis. However surgical interventions can lead to excess bleeding.[ncbi.nlm.nih.gov] Petechiae had been noted first on the day of birth. The patient's record revealed platelet counts variable between 25,000 and 150,000/mm 3.[annals.org]

  • Aspirin-induced Platelet Defect

    [top] Thrombotic Thrombocytopenic Purpura (TTP) and the VWF-Cleaving Protease (ADAMTS-13) Assay Thrombotic thrombocytopenic purpura (TTP) is caused by ultra-high molecular[uab.edu] Acquired platelet dysfunction as a cause of bleeding diathesis: two case studies. Hematol Transfus Int J. 2017;4(1):31‒34.[medcraveonline.com] To the Editor: Petechiae are small capillary hemorrhages that are characteristic of severe thrombocytopenic states.[nejm.org]

  • Aplastic Anemia

    Acquired amegakaryocytic thrombocytopenic purpura (AATP) is a rare hematological disorder characterized by severe thrombocytopenia and a complete or near-to complete absence[ncbi.nlm.nih.gov] Although the GI bleed could be explained by portal hypertension and gastropathy, the epistaxis was likely due to a bleeding diathesis secondary to thrombocytopenia.[jscisociety.com] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[merckmanuals.com]

  • Von Willebrand Disease

    An infant with presumed maternal immune thrombocytopenic purpura had persistent thrombocytopenia with platelet clumping.[ncbi.nlm.nih.gov] This leads to an increased removal of VWF multimers from the circulation as well as platelets and this results in a bleeding diathesis.[ncbi.nlm.nih.gov] Platelets function well enough that petechiae and purpura rarely occur.[merckmanuals.com]

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