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438 Possible Causes for Bleeding Diathesis, Thrombocytopenia, Thrombocytopenic Purpura

  • Immune Thrombocytopenic Purpura

    A controversy soon emerged regarding the pathologic mechanisms responsible for the thrombocytopenia.[doi.org] Immune thrombocytopenic purpura (ITP), also called primary immune thrombocytopenia or idiopathic thrombocytopenic purpura, is an autoimmune disease affecting thrombocytes.[symptoma.com] A year later she presented with bleeding diathesis and was diagnosed as ITP.[ncbi.nlm.nih.gov]

  • Kasabach Merritt Syndrome

    Title Other Names: Kasabach Merritt syndrome; Thrombocytopenia-hemangioma syndrome; Kasabach Merritt phenomenon; Kasabach Merritt syndrome; Thrombocytopenia-hemangioma syndrome[rarediseases.info.nih.gov] purpura or hypersplenism.Placental chorioangiomas are the most widespread non-trophoblastic benign tumor-like lesions of placenta.[ncbi.nlm.nih.gov] A patient can lose up to 70% of their coagulation factors before developing a clinical bleeding diathesis, so the goal is the ensure the levels of coagulation factors remain[ispub.com]

  • Disseminated Intravascular Coagulation

    Both initially received antibiotic treatment for suspected infection-associated thrombocytopenia.[ncbi.nlm.nih.gov] Bleeding diathesis must be corrected before surgery in order to prevent massive intraoperative bleeding.[kjim.org] In contrast, disseminated intravascular microthrombosis (DIT) occurs in thrombotic thrombocytopenic purpura (TTP) and TTP-like syndrome due to ADAMTS13 deficiency or insufficiency[ncbi.nlm.nih.gov]

  • Bernard-Soulier Syndrome

    The first woman presented with platelet-associated autoantibodies and thrombocytopenia, but her three newborn infants showed normal platelet count and function.[ncbi.nlm.nih.gov] Immune thrombocytopenic purpura is a diagnosis of exclusion.[pubs.sciepub.com] The propositus was a 39-year-old Japanese female with life-long bleeding diathesis.[ncbi.nlm.nih.gov]

  • Glanzmann Thrombasthenia

    Heikal, Rare complication of treated immune thrombocytopenia, American Journal of Hematology, 92, 11, (1262-1266), (2017). John E. Zvijac, Sharhabil S.[doi.org] Acquired Glanzmann's thrombasthenia (GT) is an uncommon accompaniment to immune thrombocytopenic purpura.[ncbi.nlm.nih.gov] Patients with Glanzmann thrombasthenia experience lifelong spontaneous and post-traumatic mucocutaneous bleeding diathesis.[ncbi.nlm.nih.gov]

  • Thrombocytopathy

    A patient is described who presented a thrombocytopenia with thrombocytopathy followed by the development of a leukaemia.[ncbi.nlm.nih.gov] Thrombocytopenic purpura thrombocytopenic purpura n. See idiopathic thrombocytopenic purpura.[definithing.com] Patients with thrombocytopathy due to storage pool disease mostly suffer from mild bleeding diathesis. However surgical interventions can lead to excess bleeding.[ncbi.nlm.nih.gov]

  • Bleeding Diathesis

    A complete blood count (CBC) can detect anemia and more importantly thrombocytopenia (defined as platelet count 150,000/μL), which may occur either as a result of impaired[symptoma.com] purpura.[ncbi.nlm.nih.gov] A 6-year-old girl presented with presumed relapse of childhood immune thrombocytopenia.[ncbi.nlm.nih.gov]

  • Aspirin-induced Platelet Defect

    Thrombocytopenia /absent radii (TAR syndrome) - radial aplasia or hypoplasia and thrombocytopenia. Bernard-Soulier syndrome (BSS).[patient.info] [top] Thrombotic Thrombocytopenic Purpura (TTP) and the VWF-Cleaving Protease (ADAMTS-13) Assay Thrombotic thrombocytopenic purpura (TTP) is caused by ultra-high molecular[uab.edu] Acquired platelet dysfunction as a cause of bleeding diathesis: two case studies. Hematol Transfus Int J. 2017;4(1):31‒34.[medcraveonline.com]

  • Platelet-Type Bleeding Disorder 17

    GPS is an α-granule defect associated with the development of myelofibrosis and mild to moderate thrombocytopenia.[ncbi.nlm.nih.gov] This patient had long-term thrombocytopenia which had been initially misdiagnosed as idiopathic thrombocytopenic purpura (ITP).[ncbi.nlm.nih.gov] Splenectomy was followed by normalization of platelet count but the bleeding diathesis continued.[ncbi.nlm.nih.gov]

  • Platelet Storage Pool Deficiency

    A new inherited thrombocytopenia the Paris-Trousseau syndrome associated with dysmegakaryopoiesis, giant platelet alpha granules, congenital abnormalities and mental retardation[experts.umn.edu] In myeloproliferative disorders, disseminated intravascular coagulation (DIC), following cardiopulmonary bypass, Thrombotic Thrombocytopenic Purpura (TTP), and Hemolytic Uremic[clinicaladvisor.com] Abstract Delta-granule platelet storage pool deficiency (δ-PSPD) is a poorly studied bleeding diathesis resulting from either decreased granule content or decreased average[ncbi.nlm.nih.gov]

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