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150 Possible Causes for Bleeding Diathesis, Thrombocytopenic Purpura, Vaginal Bleeding

  • Disseminated Intravascular Coagulation

    Vomiting of blood Bloody or black stools Blood in the urine Vaginal bleeding Unexplained bruises Severe abdominal or back pain Seizures or loss of consciousness in advanced[healthcommunities.com] We report on 3 male neonates with hereditary ADAMTS13 deficiency (Upshaw Schulman syndrome, USS), the inherited form of thrombotic thrombocytopenic purpura (TTP). 2 presented[ncbi.nlm.nih.gov] Bleeding diathesis must be corrected before surgery in order to prevent massive intraoperative bleeding.[kjim.org]

  • Coagulation Abnormalities

    Rectal or vaginal examination may be appropriate.[patient.info] Cancer patients may also suffer from the impediment of hemolytic uremic syndrome or thrombotic thrombocytopenic purpura (HUS/TTP).[als-journal.com] diathesis.[ncbi.nlm.nih.gov]

  • Von Willebrand Disease

    An infant with presumed maternal immune thrombocytopenic purpura had persistent thrombocytopenia with platelet clumping.[ncbi.nlm.nih.gov] It is acknowledged that vaginal bleeding is common during first trimester of pregnancy.[ncbi.nlm.nih.gov] This leads to an increased removal of VWF multimers from the circulation as well as platelets and this results in a bleeding diathesis.[ncbi.nlm.nih.gov]

  • Immune Thrombocytopenic Purpura

    Most deliveries (82.4%) were vaginal. Bleeding was uncommon at delivery.[ncbi.nlm.nih.gov] Immune thrombocytopenic purpura (ITP), also called primary immune thrombocytopenia or idiopathic thrombocytopenic purpura, is an autoimmune disease affecting thrombocytes.[symptoma.com] A year later she presented with bleeding diathesis and was diagnosed as ITP.[ncbi.nlm.nih.gov]

  • Glanzmann Thrombasthenia

    Acquired Glanzmann's thrombasthenia (GT) is an uncommon accompaniment to immune thrombocytopenic purpura.[ncbi.nlm.nih.gov] Three episodes of epistaxis and an episode of vaginal bleeding were managed conservatively. She had received 60 units of blood transfusion over a period of 1 year.[bjo.bmj.com] Patients with Glanzmann thrombasthenia experience lifelong spontaneous and post-traumatic mucocutaneous bleeding diathesis.[ncbi.nlm.nih.gov]

  • Bernard-Soulier Syndrome

    Immune thrombocytopenic purpura is a diagnosis of exclusion.[pubs.sciepub.com] Her vaginal bleeding was controlled by platelet infusion and recombinant factor 7 infusion.[ijmyco.org] The propositus was a 39-year-old Japanese female with life-long bleeding diathesis.[ncbi.nlm.nih.gov]

  • Bleeding Diathesis

    purpura.[ncbi.nlm.nih.gov] Clinical Features of Bleeding Disorders Platelet disorders Coagulation factor disorders Site of bleeding tissues Skin Mucous membranes (epistaxis, gum, vaginal, GI tract)[slideshare.net] Bleeding diathesis is a term describing a propensity toward bleeding or hemorrhage, which can be a constitutive feature of numerous disorders of vascular, genetic, or autoimmune[symptoma.com]

  • Genetic Anomaly of Leukocytes

    “Is bone marrow aspiration needed in acute childhood idiopathic thrombocytopenic purpura to rule out leukemia”.[clinicaladvisor.com] Thrombocytopenia, giant platelets and Leukocyte inclusion bodies in a patient presenting with vaginal bleeding.[ijpmonline.org] Thrombocytopenia of the May-Hegglin anomaly type was diagnosed in a woman with no past history of bleeding diathesis, who had been followed during her three pregnancies.[ncbi.nlm.nih.gov]

  • Acquired Hemophilia A

    ., idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, connective tissue disorders and autoimmune hemolytic anemia) in which it has been used with the[ncbi.nlm.nih.gov] In this case report, we present a non-hemophiliac patient, who presented five months postpartum with intermittent heavy vaginal bleeding, easy bruising, hemarthrosis, and[ncbi.nlm.nih.gov] In any elderly patient with a bleeding diathesis and an abnormality in intrinsic coagulation, the presence of inhibitors to factor VIII should be suspected.[ncbi.nlm.nih.gov]

  • Thrombocytopathy

    Thrombocytopenic purpura thrombocytopenic purpura n. See idiopathic thrombocytopenic purpura.[definithing.com] It usually occurs with painless vaginal bleeding that develops slowly at the beginning.[aneskey.com] Patients with thrombocytopathy due to storage pool disease mostly suffer from mild bleeding diathesis. However surgical interventions can lead to excess bleeding.[ncbi.nlm.nih.gov]

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