Create issue ticket

168 Possible Causes for Bleeding Gums, Bone Pain, Macrocytosis

  • Multiple Myeloma

    (who, 2001) Malignant neoplasm of plasma cells usually arising in the bone marrow and manifested by skeletal destruction, bone pain, and the presence of anomalous immunoglobulins[] – such as frequent nosebleeds, bleeding gums and heavy periods Myeloma doesn't usually cause a lump or tumour.[] However, if you have these symptoms, you should call your doctor right away: Fever Bleeding (such as nosebleeds, bleeding gums or severe bruising) Skin rash Cough that doesn[]

  • Infantile Scurvy

    Patients may present with lethargy and malaise, bone pain, bleeding diathesis (e.g. bleeding gums), and impaired wound healing.[] Signs of scurvy include tiredness, muscle weakness, joint and muscle aches, a rash on the legs, and bleeding gums.[] pain.[]

  • Myeloproliferative Disease

    Symptoms Signs  Fatigue  Malaise  Early satiety  Weight loss  Fever  Abdominal painBone pain  Pruritis  Splenomegaly  Abnormal blood counts  Abnormal peripheral[] , and/or symptoms of thrombosis Nosebleeds Headache Vision problems Bleeding gums Gastrointestinal bleeding Blood in the urine High blood pressure Blockage of blood vessels[] Abstract Children with Down syndrome (DS) display macrocytosis, thrombocytosis, and a 500-fold increased risk of developing megakaryocytic leukemia; however, the specific[]

  • B Acute Lymphoblastic Leukemia

    .: Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia. Nat Genet 47 (5): 535-8, 2015.[] Bone pain is relatively common and described in approximately 50% of patients (1, 7). Pain may also occur in the course of the disease or during treatment.[] gums, or other unusual bleeding such as from minor cuts Depending upon where leukemia cells are present, other symptoms may include: A full or swollen belly from leukemia[]

  • Acute Erythroblastic Leukemia

    Other typical symptoms include fever, pain in the joints and bones, and swelling of the lymph nodes, spleen, and liver. adj., adj leuke mic. Types of Leukemia .[] Blood smear shows nucleated red cells at different stages with pathological features (macrocytosis, schistocytes, blast cells Bone marrow biopsy shows prevalence of erythroid[] […] from the gums, retinal hemorrhages, and infections of the respiratory tracts, urinary tracts, sinuses, peri-rectal areas, and skin.[]

  • Severe Aplastic Anemia

    Mild anemia and macrocytosis may indicate SAA in patients otherwise possibly diagnosed with immune thrombocytopenic purpura.[] Radiation therapy- radiation may help a small number of people who have bone pain. It can also help reduce the size of the spleen, when surgical removal isn't an option.[] The intraoral examination identified bleeding gums; petechiae of the palate, tongue and cheek mucosa; and an atrophic, smooth and shining dorsal surface of the tongue.[]

  • Vitamin B12 Deficiency

    We report a case of a 46-year-old Moroccan man presenting with severe hemolytic anemia, thrombocytopenia, and renal failure in absence of macrocytosis, thus mimicking a genuine[] Regarding the leg pain, it can be due to the growth of the bones and muscles in children. These generally settle down with time.[] gums Long-term vitamin B12 deficiency can cause: Confusion Dementia Depression Loss of balance Numbness and tingling in your hands and feet Treatment of Vitamin B12 Deficiency[]

  • Pellagra

    Osteomalacia Osteomalacia is characterized by pain, sometimes severe, in bones, particularly in the pelvis, lower back and legs.[] FEX: Use of case definitions and awareness of micronutrient deficiencies Summary of Unpublished Study* Afgani boy with swollen and bleeding gums typical of scurvy.[] It famously afflicted sailors exploring the New World, and its symptoms include fatigue; irritability; depression; and bleeding from the gums, under the skin, and around bones[]

  • Vitamin Deficiency

    […] erythropoiesis (formation of erythrocytes), it is important for pharmacists to note that microcytosis (low mean corpuscle volume: [MCV]) should suggest sideroblastic anemia, while macrocytosis[] Vitamin D – bowing of legs in children, periosteal bone pain and osteomalacia in adults.[] Bleeding gums Take care of your teeth properly and if you still have bleeding gums, it can indicate a vitamin deficiency.[]

  • Gingivitis

    Periodontal disease is a severe and painful infection that has spread extensively through the soft gum tissues and may be attacking the nearby bone.[] What Diseases Can Cause my Gums to Bleed? Periodontitis (or gum disease) is one of the leading causes of bleeding gums.[] Moreover, of the 92 GPCA /DG /EOLP patients, 24 had macrocytosis, and only 13 (54.2%) of these 24 patients had pernicious anemia.[]

Similar symptoms