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110 Possible Causes for Blepharitis, Sore Mouth, T Cell Activation Increased

  • Hypersensitivity

    These sores can be found on the genitals, vagina, anus, rectum, lips and mouth. Pregnant women can transmit the disease to their unborn child.[niaid.nih.gov] However, increased activation of CD4 T-cell and CD8 T-cells was only observed following four days of DDAB exposure.[ncbi.nlm.nih.gov] It is transmitted from person to person via direct contact with a syphilitic sore, known as a chancre.[niaid.nih.gov]

  • Food Allergy

    Memory T cells are increased in frequency and have distinct activation requirements and cell-surface proteins that distinguish them from armed effector T cells 10-25.[ncbi.nlm.nih.gov] […] defects of permanent teeth Adults are less likely to have digestive signs and symptoms and may instead have one or more of the following: anemia bone or joint pain canker sores[web.archive.org] These sores can be found on the genitals, vagina, anus, rectum, lips and mouth. Pregnant women can transmit the disease to their unborn child.[niaid.nih.gov]

  • Sjögren Syndrome

    Human exposure to an extremely high dose of TCDD in vivo induced a selective increase in the frequency of T cells producing IL-22 but not IL-17, IL-10, or IFN-γ ( 69 ).[doi.org] Other symptoms may include: Contact lens discomfort Dry sinuses and frequent sinus infections or nosebleeds Sore mouth, tongue or throat Difficulty chewing or swallowing Dry[allaboutvision.com] Private practitioners were more likely to use symptom questionnaires and grading scales and to describe anterior blepharitis.[ncbi.nlm.nih.gov]

  • Discoid Lupus Erythematosus

    A 28-year-old woman presented with a 2-year history of idiopathic, chronic blepharitis unresponsive to several courses treatment of corticosteroid eye drops.[ncbi.nlm.nih.gov] Mouth ulcers Formation of thick scales may spread to the interior region of the mouth, causing open sores or oral ulcers.[phaa.com] Intracellular calcium is increased in activated T cells and binds to calmodulin, which activates calcineurin, a calcium-activated phosphatase.[rheumatology.oxfordjournals.org]

  • Common Cold

    cell proliferation, 15 shifts in T helper cell cytokine responses, 16,, 17 decreases in natural killer (NK) cell cytotoxicity, 18,, 19 and increased activation of proinflammatory[doi.org] The person may develop cold sores around the mouth, and the lips can be chapped and cracked.[uofmhealth.org] You can also catch a cold by touching contaminated objects and surfaces and then touching your eyes, nose or mouth.[vicks.com]

  • Atopic Dermatitis

    These early effects lead to increased histamine release from IgE-activated mast cells and elevated activity of the T-helper cell–mediated immune system.[emedicine.medscape.com] Adverse events experienced with dupilumab included injection site reactions, eye and eyelid inflammation, and cold sores on the mouth or lips, according to a Regeneron statement[mdedge.com] It is frequently associated with eyelid dermatitis and chronic blepharitis and may result in visual impairment from corneal scarring.[theasthmacenter.org]

  • Allergic Rhinitis

    We found that IL-1R8 expression was very low on dendritic cells (DCs) and resting CD4 T cells but increased strongly on CD4 T cells following T cell activation.[ncbi.nlm.nih.gov] Symptoms for hay fever usually include: An itchy nose, mouth, eyes or skin A runny nose and/or stuffy nose Sneezing Watery eyes Sore throat Food allergies and eczema According[nationaleczema.org] Symptoms include runny nose; sneezing; itchy nose, mouth, throat, or eyes; and congestion.[medbroadcast.com]

  • Psoriasis

    The psoriatic lesions are linked with increased T-cell activity beneath the underlying skin area.[symptoma.com] […] loss, sun sensitivity, headaches, joint and muscle pain, hepatotoxicity, dyslipidemia, inhibition of bone growth Systemic methotrexate: gastrointestinal upsets, nausea, oral[clinicaladvisor.com] An elderly male with palmoplantar psoriasis developed periocular psoriasis in the form of blepharitis and conjunctivitis following an external dacryocystorhinostomy as a manifestation[ncbi.nlm.nih.gov]

  • Stevens-Johnson Syndrome

    […] normal T-cell expressed and secreted (RANTES), IL-7, IL-12p70 and IL-13, with maximal increase in GM-CSF and maximal downregulation of IP-10, respectively.[ncbi.nlm.nih.gov] The initial signs of SJS are bloody crusts on the lips, a sore mouth that has a foul smell, and purple-red tender spots on the skin.[childrensclinicofraceland.com] Ocular symptoms: painful red eye, purulent conjunctivitis, photophobia, blepharitis.[patient.info]

  • Tertiary Syphilis

    This abnormal response to therapy is most likely due to immune dysfunction related to the increased polyclonal B cell activation found in HIV infection rather than a true[antimicrobe.org] These symptoms may include a rash (over the entire body or just on palms of hands and soles of feet), a sore in the mouth, sore throat, swollen and painful joints, aching[goaskalice.columbia.edu] You can find sores on or around the penis, vagina, or anus, or in the rectum, on the lips, or in the mouth.[cdc.gov]

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