Blindness: Causes & Reasons

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Possible Causes for Blindness

Common Cold

METHODS: A randomized, double-blind, double-dummy, parallel, positive- controlled trial included 72 CCWHS patients was performed. [ncbi.nlm.nih.gov]

DESIGN: A double blind randomized placebo-controlled clinical trial. [ncbi.nlm.nih.gov]

Randomised, double-blind, controlled trials comparing corticosteroids to placebo or to standard clinical management. [ncbi.nlm.nih.gov]

Hypertension

METHODS: This 8-week, active-controlled, parallel-group, fixed-dose, multicenter, double-blind randomized controlled, and noninferiority trial was conducted at 17 cardiovascular [ncbi.nlm.nih.gov]

Blinding We distinguished trials by the methods of blinding, i.e. double‐blind, blood pressure observer blind, or open study. 3. [dx.doi.org]

single-blind or open label; 3) Parallel or crossover trial; 4) For crossover trial, a washout period of at least two weeks; 5) Minimum treatment duration of four weeks; [ncbi.nlm.nih.gov]

Diabetes Mellitus

METHODS: In a double-blind multicentre parallel-group randomised controlled trial, adults with type 2 diabetes mellitus were randomly allocated to receive 25 sessions of either [ncbi.nlm.nih.gov]

As well, early detection and treatment of vision-threatening retinopathy can prevent or delay blindness. [web.archive.org]

Diabetic retinopathy (eye disease) Etiology Diabetic retinopathy is a leading cause of blindness and visual disability. [web.archive.org]

Acute Bronchitis

DESIGN, SETTING AND PARTICIPANTS: Randomised, triple blind, placebo controlled equivalence trial of amoxicillin compared with placebo in 660 adults presenting to two outpatient [ncbi.nlm.nih.gov]

[…] bronchitis and without confounding co-morbidity or co-medication were randomly assigned to treatment with either Myrtol 300 mg 4 times daily or matched placebo in double-blind [ncbi.nlm.nih.gov]

RESEARCH DESIGN AND METHODS: This was a randomised, double-blind, placebo-controlled, multicentre study with 217 patients aged between 18 and 66 years with acute bronchitis [ncbi.nlm.nih.gov]

Eyeball Injury

[…] champion Shinsuke Nakamura connected with a head kick that left the wrestler in agony and the match cancelled Video 29th October 2016, 10:07 am WWE star Austin Aries was almost blinded [thesun.co.uk]

Will a baby’s prematurity cause blindness? What can be done to prevent blindness from Retinopathy of Prematurity? Not all prematurity results in blindness. [vrsp.org.ph]

Will I eventually become blind or poorly sighted later in life because of my nearsightedness? [vrsp.org.ph]

Keratitis

Delays in diagnosis and treatment of keratitis can lead to serious complications, including blindness. [preventblindness.org]

[…] of blind people globally [4]. [bmcophthalmol.biomedcentral.com]

Examples include snow blindness or welder’s arc eye. [aao.org]

Migraine

Gibson, RG, Gibson, SLM, MacNeill, AD, Buchanan, WW Homoeopathic therapy in rheumatoid arthritis: evaluation by double-blind clinical therapeutic trial. [doi.org]

The primary endpoint was the proportion of subjects taking DFN-11 who were pain free at 2 h postdose in the double-blind period compared with placebo. [ncbi.nlm.nih.gov]

METHODS: In this randomized, double-blind, single-center controlled trial, patients with 6 to 15 migraine attacks per month, which were candidates of preventive treatment, [ncbi.nlm.nih.gov]

Transient Ischemic Attack

Common symptoms are sudden and transient, and include unilateral paresis, speech disturbance, and monocular blindness. [ncbi.nlm.nih.gov]

We report an 8-year-old girl with MELAS, presenting with a seizure and blindness. 1H-MRS showed a strikingly elevated lactate peak in the right occipital region, where no [ncbi.nlm.nih.gov]

Compared with neurologists, GPs considered "confusion" and "unexplained fall" more often compatible with TIA and "lower facial palsy" and "monocular blindness" less often [ncbi.nlm.nih.gov]

Glaucoma

Fighting Blindness offers a free and confidential counselling service (Insight Counselling). [fightingblindness.ie]

Published on Dec 2, 2014 (Visit: ) Glaucoma is the leading cause of irreversible blindness worldwide. Dr. [youtube.com]

The paper by Resnikoff et al. reports that about 37 million people worldwide in 2002 were blind. More than 82% of all blind people are 50 years and older. [who.int]

Epilepsy

MAIN RESULTS: No double-blind randomised controlled trials met the inclusion criteria. [ncbi.nlm.nih.gov]

Trembly 1990 was a partially single‐blind and partially double‐blind study, with no details of the investigator‐blinding provided. [doi.org]

Although all included studies were reported as double‐blinded, blinding was not explicitly reported in all trials. [doi.org]

Cataract

Cataract is the leading cause of blindness, accounting for 50% of blindness worldwide. [ncbi.nlm.nih.gov]

blindness in China was unmasked. [ncbi.nlm.nih.gov]

Cataracts can appear in one or both eyes and if left untreated, they may result in blindness. [fightingblindness.ie]

Macular Degeneration

British surgeons have taken a “big step forward” towards curing the most common form of blindness by developing and successfully performing a ground breaking operation. [independent.co.uk]

However, after performing surgery on the 60-year patient, who was classified as legally blind, surgeons are optimistic of a breakthrough, although the full impact on her sight [independent.co.uk]

The treatment itself leaves permanent blind spots in a person’s vision. [preventblindness.org]

Retinitis Pigmentosa

LAWRENCE — Going blind after college, Steve Lonegan couldn't land a job. [nj.com]

RP typically manifests with poor vision in dimly lit environments, termed "night blindness." [afb.org]

Other Useful Links RP Fighting Blindness www.rpfightingblindness.org.uk [fightingblindness.ie]

Uveitis

Uveitis causes about 30,000 new cases of blindness each year in the United States. [preventblindness.org]

Ross, who is now blind, likes to tease that she met her husband, George, on a blind date. At the end of the night, he took her hands in his. [cnn.com]

If left untreated, it can result in vision loss and blindness. [nvisioncenters.com]

Gingivitis

MATERIALS AND METHODS: Randomized, double blind clinical trial was designed. Thirty first year dental students volunteered to participate in the study. [ncbi.nlm.nih.gov]

MATERIALS AND METHODS: This randomized, double-blinded, crossover clinical trial included 40 participants aged 18 to 35 years with washout period of 1 week between the crossover [ncbi.nlm.nih.gov]

Material and Methods: A prospective, double-blind, randomized, controlled clinical trial was carried out on 20 patients; it is divided into an experimental group and a control [ncbi.nlm.nih.gov]

Osteoarthritis

[…] of the bibliographic databases Medline, Embase, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews for randomised, double-blind [ncbi.nlm.nih.gov]

We will conduct a single center, parallel group, superiority randomized controlled trial comparing DPT and NS injections, with blinding of physician, participants, outcome [ncbi.nlm.nih.gov]

[…] of the bibliographic databases Medline, Embase, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews for randomised, double‐blind [doi.org]

Occlusion of the Ophthalmic Artery

A 49-year-old woman with diabetes mellitus and hyperlipidemia experienced frequent transient monocular blindness in the right eye during a 3-week period. [ncbi.nlm.nih.gov]

[…] use of newer agents for embolotherapy may cause migration of embolic material from the external to the internal carotid system leading to ophthalmic artery occlusion and blindness [ncbi.nlm.nih.gov]

Ryan Springer Science & Business Media, ٢٩‏/٠٣‏/٢٠١٠ - 779 من الصفحات Vascular diseases of the retina are a major cause of blindness among all age groups. [books.google.com]

Acne Vulgaris

Methods: This was a randomized double-blind clinical trial performed in 60 patients with mild to moderate acne vulgaris. [doi.org]

METHODS: This was a randomized double-blind clinical trial performed in 60 patients with mild to moderate acne vulgaris. [ncbi.nlm.nih.gov]

METHODS: We conducted a pooled subgroup analysis of 2 randomized, double-blind, vehicle-controlled clinical trials conducted in the US and Canada. [ncbi.nlm.nih.gov]

Diabetic Angiopathy

Retinal damage (from microangiopathy) makes it the most common cause of blindness among non-elderly adults in the US. [en.wikipedia.org]

In diabetic retinopathy the end-result is often blindness due to irreversible retinal damage. Diagnosis[edit] This section is empty. You can help by adding to it. [en.wikipedia.org]

Carotid Artery Occlusion

Contrarily, transient attacks of blindness associated with hemiplegia progress to permanent optic atrophy, as the attacks of hemiplegia stop. [ijo.in]

Two neuroradiologists reviewed CTA images for the presence or absence of extracranial ICA occlusion, blinded to the catheter angiography results. [ncbi.nlm.nih.gov]

The second part compose of a prospective superiority trial, rater blinded, with 1:1 randomization to evaluate the clinical efficacy of interventional therapy for CAO. [clinicaltrials.gov]

Skull Fracture

Basilar fractures have several symptoms unique to this type of fractured skull, including: ataxia nystagmus facial palsy hearing loss loss of smell facial nerve damage blindness [healthblurbs.com]

(adults call it "bilateral periorbital haematoma") CSF rhinorrhoea Cranial nerve abnormalities: CNI damage (loss of olfaction) CN II entrapment (visual field defects or blindness [derangedphysiology.com]

At the blind end, it is more tapered than it is at the sutural or proximal end. Note the lack of branches. [emedicine.medscape.com]

Vaginal Candidiasis

Prospective randomized open blinded end-point (PROBE) study. A novel design for intervention trials. Prospective Randomized Open Blinded End-Point. [doi.org]

International Phase III, Randomised, Multi-centre, Parallel-group, Two Arm, Double-blind Superiority Trial Versus Placebo. [malacards.org]

[…] among HIV-infected women, weekly intravaginal application of Lactobacillus acidophilus or weekly intravaginal application of clotrimazole tablets, in a randomized, double-blind [ncbi.nlm.nih.gov]

Actinic Keratosis

METHODS: A multicenter, randomized, double-blinded phase III trial was conducted. [ncbi.nlm.nih.gov]

Non-blinded quantitative measurements of vascular diameter were also performed. [ncbi.nlm.nih.gov]

AIM: We evaluated in a multicenter, assessor-blinded, 3 month trial the efficacy of ACTX in AK. [ncbi.nlm.nih.gov]

Carotid Embolism

Transient monocular blindness associated with hemiplegia. Arch. Ophthal. Chicago195247167–203.Fisher [C.] M. Transient monocular blindness associated with hemiplegia. [thejns.org]

September 01, 1981; 31 (9) Article First published September 1, 1981, DOI: Abstract a 63-year-old hypertensive woman with a prolapsing mitral valve developed sudden blindness [n.neurology.org]

Blindness after fat injections. N Engl J Med. 2011 ; 365 : 2220. 18.. Fat embolism. Anesthesiol Clin. 2009 ; 27 : 533 – 550. 19.. [academic.oup.com]

Retinal Artery Embolism

Transient monocular blindness associated with hemiplegia. Arch Ophthalmol 1952; 57: 167–203. Google Scholar 3. Fisher CM. [link.springer.com]

Diabeticretinopathy, corneal neovascularization, age-related macular degeneration, retinal veinocclusion, andretinopathy of prematurity are major causes of blindness. [books.google.com]

Rene et al ( 3 ) reported a case of unilateral blindness following ESS in which direct optic nerve damage occurred in combination with central retinal arterial occlusion [journals.lww.com]

Diabetic Retinopathy

Both can lead to permanent, irreversible blindness. [preventblindness.org]

If left untreated, proliferative retinopathy can cause severe vision loss and even blindness. [web.archive.org]

Kuriyan, MD, MS Diabetic eye disease is one of the leading causes of blindness and impaired vision. [preventblindness.org]

Insomnia

METHODS AND MATERIALS: This study was conducted as a 3-arm double-blind randomized trial. [ncbi.nlm.nih.gov]

Blinding Due to the nature of the intervention, it is not possible to blind participants and it can be difficult to blind personnel or researchers. [doi.org]

[…] and elderly subjects with insomnia disorder per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition were enrolled in a multicenter, randomized, double-blind [ncbi.nlm.nih.gov]

Axial Spondyloarthritis

Dual Neutralization of IL-17A and IL-17F with Bimekizumab in Patients with Active, Psa: Results from a 48-Week Phase 2b, Randomized, Double Blind, Placebo-Controlled, Dose [f1000research.com]

Efficacy and safety of infliximab plus naproxen versus naproxen alone in patients with early, active axial spondyloarthritis: results from the double-blind, placebo-controlled [rheumatic.theclinics.com]

Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN). [journals.sagepub.com]

Wolfram Syndrome

All of these patients became blind during follow-up and were unable to perform urethral CIC independently. [ncbi.nlm.nih.gov]

Neurologic Manifestations Sensation Disorders Vision Disorders Blindness Deaf-Blind Disorders Hearing Disorders Hearing Loss Deafness Deaf-Blind Disorders Neurodegenerative [hon.ch]

Appendicovesicostomy urinary diversion using the Mitrofanoff principle was performed in these six blind patients. [ncbi.nlm.nih.gov]

Susac Syndrome

Dementia, blindness, and deafness are rare late sequelae, and half of patients return to normal life. [ncbi.nlm.nih.gov]

Residual disabilities such as blindness, deafness, and dementia may also be presented in its late stages. [ncbi.nlm.nih.gov]

Wasserman Merit Award from Research to Prevent Blindness. 3. Gass JD, Tiedeman J, Thomas MA. Idiopathic recurrent branch retinal arterial occlusion. [jamanetwork.com]