Blonde Hair: Causes & Reasons

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Possible Causes for Blonde Hair

Malignant Neoplasm of the Skin

Fair hair which is often blond, but also dark blond and black hair. Skin type 3 – Sometimes red but always tans after a while. Skin type 4 – Never burns. [oncolex.org]

Race: People with fair skin, freckling or red or blond hair have a higher risk. [idph.state.il.us]

hair; and a family history of unusual moles or melanoma. [livescience.com]

Squamous Cell Carcinoma of the Skin

People at the highest risk for developing basal cell carcinoma have fair skin, red or blond hair, and green, blue, or gray eyes. [nyulangone.org]

Individuals with light-colored skin, freckled skin, blond hair, red hair, and light eyes have a greater risk for skin cancer. [innerbody.com]

Certain things can increase your chances of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [www2.hse.ie]

Classical Phenylketonuria

In addition to congenital anomalies and developmental delay, blond hair, fair skin and unusual urinary odor were noted. [ncbi.nlm.nih.gov]

This may explain why persons with phenylketonuria generally have blond hair, blue eyes, and fair skin. [britannica.com]

[…] retention of phenylalanine in other tissues also leads to a decrease in the formation of melanin, a product of tyrosine metabolism that produces the pigment found in the skin, hair [britannica.com]

Homocystinuria

The hereditary form features sparse blond hair, OSTEOPOROSIS with overgrowth of long bones, a hollowed chest, dislocation of the lenses of the eyes and mental retardation. [medical-dictionary.thefreedictionary.com]

Clinical features include a tall slender habitus, SCOLIOSIS, arachnodactyly, MUSCLE WEAKNESS, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence [fpnotebook.com]

Clinical features include a tall slender habitus, scoliosis, arachnodactyly, muscle weakness, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence [icd10data.com]

Prader-Willi Syndrome

[…] have fair skin, blonde hair and blue eyes, regardless of what their family members look like), and a turned-down mouth (Better Health Channel). [aruma.com.au]

[…] have fair skin, blonde hair and blue eyes, regardless of what their family members look like), and a turned-down mouth ( Better Health Channel ). [hwns.com.au]

Around half of all children with Prader-Willi syndrome will have fair skin, blonde hair and blue eyes, regardless of what their family members look like.Children with Prader-Willi [betterhealth.vic.gov.au]

Phenylketonuria

This may explain why persons with phenylketonuria generally have blond hair, blue eyes, and fair skin. [britannica.com]

As a result, children with PKU often will have pale skin, blond hair and blue eyes. [drugs.com]

Cartilage Hair Hypoplasia

It is a multi-systemic disorder characterized by short stature, blond fine sparse hair, but this may be quite variable, and defective cellular immunity predominantly affecting [atlasgeneticsoncology.org]

CHH is an autosomal recessive disorder characterized by skeletal involvement, short stature, variable features like blond fine sparse hair, and defective cellular immunity [karger.com]

Originally, the syndrome was believed to be characterized by unevenly short arms and legs (short limbed dwarfism), fine and light-colored hair (hypotrichosis), low levels [rarediseases.org]

Hermansky-Pudlak Syndrome Type 2

Blond hair Fair hair color Flaxen hair color Light colored hair Sandy hair color Straw colored hair Towhead (hair color) [ more ] 0002286 Gastroesophageal reflux Acid reflux [rarediseases.info.nih.gov]

Chronic oral candidiasis Chronic oral thrush 0009098 Coarse facial features Coarse facial appearance 0000280 Epicanthus Eye folds Prominent eye folds [ more ] 0000286 Fair hair [rarediseases.info.nih.gov]

ADULT Syndrome

Blonde Thin scalp hair Sparse underarm (axillary) hair Reported premature scalp hair loss (>30 years) Diagnosing ADULT Syndrome A physician can diagnose ADULT on the basis [nfed.org]

Born with blonde hair and blue eyes at 7 lbs, 5 ounces, Chris was a happy baby. [advocategiving.org]

All affected individuals have very blond, thin and sparse hair. Nails are reported to be dysplastic, and one or several teeth were lacking. [nature.com]

Actinic Keratosis

People with blonde or red hair, blue eyes, and skin type I or II are particularly susceptible (see Table: Fitzpatrick Skin Type Classification). [msdmanuals.com]

People with blonde or red hair are especially susceptible to the short-term and long-term effects of UV radiation, because they are not able to produce enough melanin. [merckmanuals.com]

Fitzpatrick Skin Type Classification Skin Type Typical Features Tanning Ability I Pale white skin; red or blond hair; blue/green eyes; freckles Always burns, never tans II [msdmanuals.com]

Acute Hepatic Porphyria

No-charge genetic testing for acute hepatic porphyria Alnylam has partnered with Invitae to offer genetic testing at no charge for individuals who may carry a gene mutation known to be associated with acute hepatic porphyria (AHP). On average, it takes up to 15 years from symptom onset for a patient to receive[…] [invitae.com]

Acute Intermittent Porphyria

Acute intermittent porphyria Other names Swedish porphyria, pyrroloporphyria, intermittent acute porphyria Porphobilinogen Specialty Medical genetics Acute intermittent porphyria (AIP) is a rare autosomal dominant metabolic disorder affecting the production of heme resulting from a deficiency of the porphobilinogen[…] [en.wikipedia.org]

Delta Aminolevulinate Dehydrase Deficiency

Gut. 1994 Aug;35(8):1112-5. Author information 1 University Department of Medicine and Therapeutics, Western Infirmary, Glasgow. Abstract Patients with acute hepatic porphyria are denied essential operations because of concern that general anaesthesia and surgery will precipitate a life threatening porphyric crisis.[…] [ncbi.nlm.nih.gov]

Smith Lemli Opitz Syndrome

Smith-Lemli-Opitz Syndrome NORD gratefully acknowledges Emily Furno, MMSc, NORD Editorial Intern from the Emory University Genetic Counseling Training Program and Cecelia A. Bellcross, PhD, MS, CGC, Associate Professor, Director, Genetic Counseling Training Program, Emory University School of Medicine, for assistance in[…] [rarediseases.org]

HAIR-AN Syndrome

The syndrome, which tends to reduce and even disappear by adulthood, is more noticeable in children who are white with pale blonde hair and can cause affected children to [newscientist.com]

Affected children have extremely frizzy, dry, generally light blonde hair, with a characteristic shine. [express.co.uk]

[…] uncombable hair syndrome [MIM*191480] a genetic syndrome in which the hair, which is often silvery blond, is unruly and resists lying flat because of irregularly shaped hair [medical-dictionary.thefreedictionary.com]

Hyperphenylalaninemia

Homepage Rare diseases Search Search for a rare disease Hyperphenylalaninemia due to tetrahydrobiopterin deficiency Disease definition Hyperphenylalaninemia (HPA) due to tetrahydrobiopterin (BH4) deficiency, also known as malignant HPA is an amino acid disorder with neonatal onset that is clinically characterized by[…] [orpha.net]

Oculocutaneous Albinism, Type 2

The majority of affected individuals develop some cutaneous melanin; this is predominantly seen as yellow/blond hair, whereas fewer have brown hair. [ncbi.nlm.nih.gov]

Symptoms - Oculocutaneous albinism type 2 * Creamy white skin * Light yellow hair * Blond hair * Light brown hair * Light-colored irises Causes - Oculocutaneous albinism type [checkorphan.org]

Their hair are usually pale blonde to golden or reddish-blonde hair. Having blue eyes is one of their common characteristics. [medigest.uk]

Oculocutaneous Albinism Type 6

Moreover, the African is not black, but an albino with blonde hair and white skin. [derm101.com]

[…] or even brown hair, and most commonly blue eyes. [en.wikipedia.org]

A little pigment can develop in freckles or moles. [6] People with OCA2 usually have fair skin but often not as pale as OCA1, and pale blonde to golden, strawberry blonde, [ipfs.io]

Oculocerebral Hypopigmentation Syndrome Type Cross

" Cross syndrome ", " hypopigmentation and microphthalmia ", and " oculocerebral-hypopigmentation syndrome ") is an extremely rare disorder characterized by white skin, blond [en.wikipediam.org]

hair with yellow-gray metallic sheen, small eyes with cloudy corneas, jerky nystagmus, gingival fibromatosis and severe menta... [encyclo.co.uk]

hair with yellow-gray metallic sheen HEENT Microcephaly Small eyes with cloudy corneas Gingival fibromatosis Neurologic Mental retardation - decreased intellectual capacity [wikidoc.org]

Oculocutaneous Albinism

hair. [ncbi.nlm.nih.gov]

Interestingly, the patient also had very light skin color, blond hair and eyebrows, and dark brown eyelashes and irises. [ncbi.nlm.nih.gov]

Individuals at birth may be misdiagnosed as OCA type I but it is common for pigmentation to increase in older individuals resulting in yellow or reddish-blond hair and the [disorders.eyes.arizona.edu]

X-Linked Recessive Ocular Albinism

He has ruddy white skin, blond hair, and blue eyes (the default colours when no pigment is present). [whitemail.blogspot.com]

The spectrum of hair pigmentation is from very >fair hair to brown hair, red hair is possible as well, although most of >them have blonde hair. [nystagmus.org]

He has blond hair and light-colored eyes. He is an only child and according to the parents, there does not seem to be a family history of this condition. [reviewofoptometry.com]

Histidinemia

Histidinemia NORD gratefully acknowledges Harvey L. Levy, MD, Senior Physician in Medicine, Children's Hospital Boston, Professor of Pediatrics, Harvard Medical School, for assistance in the preparation of this report. Synonyms of Histidinemia HAL deficiency HIS deficiency histidase deficiency histidine ammonia-lyase (HAL)[…] [rarediseases.org]

Superficial Spreading Melanoma

Certain things can increase your chances of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [www2.hse.ie]

Certain things can increase your chance of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [nhs.uk]

You are more likely to develop melanoma if you: Have fair skin, blue or green eyes, or red or blond hair Live in sunny climates or at high altitudes Spent a lot of time in [medlineplus.gov]

Uncombable Hair Syndrome

We report a family affected to the fourth generation by uncombable hair syndrome. This syndrome is characterized by unruly, dry, blond hair with a tangled appearance. [ncbi.nlm.nih.gov]

Four children had short, unmanageable, pale blond hair. They had no associated abnormalities and no family histories of abnormal hair. [ncbi.nlm.nih.gov]

Pili Torti

[…] the isolated finding of twisted hairs in two young blond-haired sisters.2 Since then, pili torti has been linked with a wide array of congenital defects, including leukonychia [ncbi.nlm.nih.gov]

[…] the isolated finding of twisted hairs in two young blond-haired sisters.22 Ronchese F. [scielo.br]

[…] the isolated finding of twisted hairs in two young blond-haired sisters. 2 Since then, pili torti has been linked with a wide array of congenital defects, including leukonychia [ncbi.nlm.nih.gov]

Acquired Kinky Hair Syndrome

Case 1 32 yo WF blonde hair, presents with a complaint of not being able to do anything with her hair, it’s not growing. [dermcast.tv]

Genetic pili torti is most frequently found in people with thin, blond hair. However, occasionally an individual may develop the hair disorder later in life. [hairdiseases.com]

GREEN HAIR. The deposition of copper on the hair, from tap water used to wash the hair (or from swimming pool water), may cause a greenish hue in blond hair. [euroformhealthcare.biz]

Loose Anagen Syndrome

Most but not all are light complexioned with fine blond hair. [emedicine.medscape.com]

Race: Most commonly noted in white skinned people, especially those with blond hair. It may, however, even be evident in case of those of Asian or African descent. 2. [lybrate.com]

Thinning, dull, lackluster blonde hair with matting over the occipital region. [emedicine.medscape.com]

Ringed Hair Disease

but other regions such as pubic, axillary, and beard hair, may also be affected.[3][10] Pili annulati is easily detected in blonde hair while it can be completely obscured [ncbi.nlm.nih.gov]

Pseudo pili annulati is most obvious in people with blond hair. It can present as natural highlights in limited areas on the scalp. [keratin.com]

Usually this hair defect is most obvious in people with blond hair as dark hair obscures the light and dark band pattern. [keratin.com]

Albinism

[…] and a tiny thin waist and male models with bleach blond hair or Herculean bodies. [people.com]

hair, violet to blue eyes and very pale skin that is particularly sensitive to the sun. [pambazuka.org]

Some patients with albinism have white hair and very light blue eyes, others have blonde hair and blue eyes, and some even have brown hair and eyes. [aapos.org]

Familial Melanoma of the Eyelid

People with fair skin that freckles or burns easily, people with blue, green or light-colored eyes, and those with red or blond hair are all at increased risk. [curetoday.com]

Certain things can increase your chances of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [nhs.uk]

Whites with red or blond hair, blue or green eyes, or fair skin that freckles or burns easily are at increased risk. [cancer.org]