Possible Causes for blonde hair Malignant Neoplasm of the Skin Race: People with fair skin, freckling or red or blond hair have a higher risk. [idph.state.il.us] hair; and a family history of unusual moles or melanoma. [livescience.com] Whites with fair skin, freckles, or red or blond hair have a higher risk of melanoma. Red-haired people have the highest risk. [skincancerprevention.org] Squamous Cell Carcinoma of the Skin People at the highest risk for developing basal cell carcinoma have fair skin, red or blond hair, and green, blue, or gray eyes. [nyulangone.org] Individuals with light-colored skin, freckled skin, blond hair, red hair, and light eyes have a greater risk for skin cancer. [innerbody.com] Red or blond hair. [web.archive.org] Actinic Keratosis […] you may be more likely to develop the condition if you: Are older than 40 Live in a sunny place Have a history of frequent or intense sun exposure or sunburn Have red or blond [mayoclinic.org] People with fair skin who sunburn easily; have trouble tanning; have blue, green, or hazel eyes; and red or blond hair are most at risk for developing actinic keratoses. [skinsight.com] Epidemiology AK occurs most often in individuals with fair skin, blonde hair and blue eyes at a rate according to cumulative UV exposure. [patient.info] Acute Hepatic Porphyria Alnylam presented results from their phase 3 ENVISION trial, which assessed givosiran for acute hepatic porphyria (AHP), at the European Association for the Study of the Liver (EASL) International Liver Congress in Vienna, Austria. ENVISION was a randomized, double-blind, placebo-controlled, global, multicenter study[…] [trialsitenews.com] Acute Intermittent Porphyria Acute intermittent porphyria (AIP) is the most common hepatic porphyria. Its clinical presentation includes severe disabling and life-threatening neurovisceral symptoms and acute psychiatric symptoms. These symptoms result from the overproduction and accumulation of porphyrin precursors, 5-aminoleuvulinic acid (ALA)[…] [ncbi.nlm.nih.gov] Classical Phenylketonuria In addition to congenital anomalies and developmental delay, blond hair, fair skin and unusual urinary odor were noted. [ncbi.nlm.nih.gov] This may explain why persons with phenylketonuria generally have blond hair, blue eyes, and fair skin. [britannica.com] […] retention of phenylalanine in other tissues also leads to a decrease in the formation of melanin, a product of tyrosine metabolism that produces the pigment found in the skin, hair [britannica.com] Phenylketonuria This may explain why persons with phenylketonuria generally have blond hair, blue eyes, and fair skin. [britannica.com] As a result, children with PKU often will have pale skin, blond hair and blue eyes. [drugs.com] […] retention of phenylalanine in other tissues also leads to a decrease in the formation of melanin, a product of tyrosine metabolism that produces the pigment found in the skin, hair [britannica.com] Prader-Willi Syndrome […] have fair skin, blonde hair and blue eyes, regardless of what their family members look like), and a turned-down mouth (Better Health Channel). [aruma.com.au] […] have fair skin, blonde hair and blue eyes, regardless of what their family members look like), and a turned-down mouth ( Better Health Channel ). [hwns.com.au] Around half of all children with Prader-Willi syndrome will have fair skin, blonde hair and blue eyes, regardless of what their family members look like.Children with Prader-Willi [betterhealth.vic.gov.au] Rosacea It is also more common in people who are fair-skinned and have blond hair and blue eyes. There are also genetic links to rosacea. [healthline.com] Smith Lemli Opitz Syndrome Smith-Lemli-Opitz syndrome is a rare autosomal recessive disorder of cholesterol biosynthesis which is characterized by multiple congenital malformations and global developmental delay. Here we report the case of a 3-year-old, previously undiagnosed, child with Smith-Lemli-Opitz syndrome presenting with acute adrenal[…] [ncbi.nlm.nih.gov] Homocystinuria The hereditary form features sparse blond hair, OSTEOPOROSIS with overgrowth of long bones, a hollowed chest, dislocation of the lenses of the eyes and mental retardation. [medical-dictionary.thefreedictionary.com] Clinical features include a tall slender habitus, SCOLIOSIS, arachnodactyly, MUSCLE WEAKNESS, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence [fpnotebook.com] Clinical features include a tall slender habitus, scoliosis, arachnodactyly, muscle weakness, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence [icd10data.com] Cartilage Hair Hypoplasia It is a multi-systemic disorder characterized by short stature, blond fine sparse hair, but this may be quite variable, and defective cellular immunity predominantly affecting [atlasgeneticsoncology.org] CHH is an autosomal recessive disorder characterized by skeletal involvement, short stature, variable features like blond fine sparse hair, and defective cellular immunity [karger.com] In most individuals, the hair also tends to be blonde or light colored. [rarediseases.org] Hyperphenylalaninemia OBJECTIVES: To assess the incidence of tetrahydrobiopterin (BH4) deficiency among patients with hyperphenylalaninemia (HPA) in southern Chinese and evaluate clinical outcome and gene mutations in tetrahydrobiopterin deficient patients. METHODS: Urinary neopterin (N) and biopterin (B) was analyzed in 87 patients[…] [ncbi.nlm.nih.gov] Sunburn How soon a sunburn begins depends on: Your skin type The sun's intensity How long you're exposed to the sun A blonde-haired, blue-eyed woman sunbathing in Rio de Janeiro will [webmd.com] If your child has red or blond hair, he is at higher risk. Fair-skinned children and children who never tan are also at higher risk. [seattlechildrens.org] This is especially true if your child has red or blond hair. Put sunscreen on 30 minutes before exposure to the sun. This gives it time to get down into the skin. [seattlechildrens.org] Basal Cell Carcinoma Other risk factors include fair complexions in skin that freckles & burns easily; blue or green or other light-colored eyes; red or blond hair, actinic keratosis, a history [texaschildrens.org] The risk of basal cell carcinoma is higher among people who freckle or burn easily or who have very light skin, red or blond hair, or light-colored eyes. Your sex. [mayoclinic.org] The risk of basal cell carcinoma is higher among people who freckle or burn easily or who have very light skin, red or blond hair, or light-colored eyes. Increasing age. [mayoclinic.org] Superficial Spreading Melanoma Less strong factors include blue or green eyes, red or blond hair, indoor occupation with outdoor recreation and signs of sun damage. [dermnetnz.org] Certain things can increase your chances of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [www2.hse.ie] Certain things can increase your chance of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [nhs.uk] Oculocutaneous Albinism, Type 2 The majority of affected individuals develop some cutaneous melanin; this is predominantly seen as yellow/blond hair, whereas fewer have brown hair. [ncbi.nlm.nih.gov] Their hair are usually pale blonde to golden or reddish-blonde hair. Having blue eyes is one of their common characteristics. [medigest.uk] Symptoms - Oculocutaneous albinism type 2 * Creamy white skin * Light yellow hair * Blond hair * Light brown hair * Light-colored irises Causes - Oculocutaneous albinism type [checkorphan.org] Oculocerebral Hypopigmentation Syndrome Type Cross hair with yellow-gray metallic sheen, small eyes with cloudy corneas, jerky nystagmus, gingival fibromatosis and severe menta... [encyclo.co.uk] " Cross syndrome ", " hypopigmentation and microphthalmia ", and " oculocerebral-hypopigmentation syndrome ") is an extremely rare disorder characterized by white skin, blond [en.wikipediam.org] hair with yellow-gray metallic sheen HEENT Microcephaly Small eyes with cloudy corneas Gingival fibromatosis Neurologic Mental retardation - decreased intellectual capacity [wikidoc.org] HAIR-AN Syndrome Affected children have extremely frizzy, dry, generally light blonde hair, with a characteristic shine. [express.co.uk] “I want to have Rapunzel’s blond hair,” she says with a shy smile. “So it can be so long and longer than the whole world.” [metroparent.com] Uncombable hair syndrome is typically diagnosed between birth and age 3, and the hair is almost always white or strawberry blonde. [insideedition.com] Oculocutaneous Albinism Type 6 Moreover, the African is not black, but an albino with blonde hair and white skin. [derm101.com] […] or even brown hair, and most commonly blue eyes. [en.wikipedia.org] A little pigment can develop in freckles or moles. [6] People with OCA2 usually have fair skin but often not as pale as OCA1, and pale blonde to golden, strawberry blonde, [ipfs.io] Histidinemia Histidinemia, is a rare autosomal recessive metabolic disorder caused by a deficiency of the enzyme histidase. Histidase is needed for the metabolism of the amino acid histidine. [1] Although originally thought to be linked to multiple developmental disorders histidinemia is now accepted as a relatively benign disorder,[…] [en.wikipedia.org] Oculocutaneous Albinism hair. [ncbi.nlm.nih.gov] Interestingly, the patient also had very light skin color, blond hair and eyebrows, and dark brown eyelashes and irises. [ncbi.nlm.nih.gov] Individuals at birth may be misdiagnosed as OCA type I but it is common for pigmentation to increase in older individuals resulting in yellow or reddish-blond hair and the [disorders.eyes.arizona.edu] Uncombable Hair Syndrome We report a family affected to the fourth generation by uncombable hair syndrome. This syndrome is characterized by unruly, dry, blond hair with a tangled appearance. [ncbi.nlm.nih.gov] Four children had short, unmanageable, pale blond hair. They had no associated abnormalities and no family histories of abnormal hair. [ncbi.nlm.nih.gov] Uncombable hair syndrome is typically diagnosed between birth and age 3, and the hair is almost always white or strawberry blonde. [insideedition.com] Pili Torti […] the isolated finding of twisted hairs in two young blond-haired sisters. 2 Since then, pili torti has been linked with a wide array of congenital defects, including leukonychia [ncbi.nlm.nih.gov] Each twist is 0.4-0.9 mm wide and occurs in groups of 3 to 10. 3, 7 The twisted hair is fragile and easily brittle on the scalp. 4 Blond hair tends to be scarce, opaque, lusterless [ncbi.nlm.nih.gov] Lusterless, opaque, scarce blond hair. Pili torti. Thick, coarse and brittle hair in the left occipitotemporal region. Pili torti. [ncbi.nlm.nih.gov] Loose Anagen Syndrome Race: Most commonly noted in white skinned people, especially those with blond hair. It may, however, even be evident in case of those of Asian or African descent. 2. [lybrate.com] The classic patient with Loose Anagen Syndrome is a girl aged 2-5 years with blonde hair; however, cases of Loose Anagen Syndrome in boys, in adults and in individuals with [hairmedic.co.uk] Most but not all are light complexioned with fine blond hair. [emedicine.medscape.com] X-Linked Recessive Ocular Albinism He has ruddy white skin, blond hair, and blue eyes (the default colours when no pigment is present). [whitemail.blogspot.com] The spectrum of hair pigmentation is from very fair hair to brown hair, red hair is possible as well, although most of them have blonde hair. [nystagmus.org] He has blond hair and light-colored eyes. He is an only child and according to the parents, there does not seem to be a family history of this condition. [reviewofoptometry.com] Skin Neoplasm hair ____% of melanomas occur on sun exposed area in white skinned people ____% of melanomas in dark-skinned individuals on non-sun-exposed areas. one half unlike the other [quizlet.com] People who are at the highest risk for developing this disease have fair skin and blonde or red hair and blue, green, or grey eyes. [reliantmedicalgroup.org] Although anyone can get skin cancer, the risk is greatest in people who have fair or freckled skin that burns easily, light eyes and blond or red hair. [my.clevelandclinic.org] Malignant Melanoma of the Skin Other risk factors include UV exposure (sunlight or tanning booths), history of blistering sunburns, dysplastic nevi, large numbers of ordinary moles, red or blonde hair, [dermspecpa.com] People with white skin color, red or blond hair, light blue or green eyes, freckles, and those who have difficulty tanning (never tan or tan minimally) have the highest incidence [myhealth.va.gov] Certain things can increase your chances of developing melanoma, such as having: lots of moles or freckles pale skin that burns easily red or blonde hair a close family member [nhs.uk] Acquired Kinky Hair Syndrome Case 1 32 yo WF blonde hair, presents with a complaint of not being able to do anything with her hair, it’s not growing. [dermcast.tv] Genetic pili torti is most frequently found in people with thin, blond hair. However, occasionally an individual may develop the hair disorder later in life. [hairdiseases.com] GREEN HAIR. The deposition of copper on the hair, from tap water used to wash the hair (or from swimming pool water), may cause a greenish hue in blond hair. [euroformhealthcare.biz] Woolly Hair Nevus It is clinically characterized by spun-glass, silvery-blonde hair. [yumpu.com] Patients affected with this condition present two distinct hair populations: straight, blond or brown, long hair shafts interspaced with short, fine, hypopigmented and curly [miami.pure.elsevier.com] […] autosomal dominant trait or a sporadic structural hair abnormality. [2] Clinically, the hair is dry, coarse, usually blond to light brown with a tangled appearance. [ijdvl.com]
