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19 Possible Causes for Blood Urea Nitrogen Increased, Burr Cell, Thrombotic Thrombocytopenic Purpura

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Thrombotic thrombocytopenic purpura associated with ticlopidine-Thrombotic Thrombocytopenic Purpura (TTP) 271 a review of 60 cases. Ann Intern Med 1998;128: 541–544.[doi.org] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Uremic Pneumonitis

    Diagnosis Peripheral blood smear establishes the presence of MAHA by schistocytes, burr cells, helmet cells etc.[omicsonline.org] The authors conclude that “initiation of dialysis at higher BUN [blood urea nitrogen] concentrations was associated with an increased risk for death.”[cjasn.asnjournals.org] Hematologic and associated serologic findings of HUS thrombotic microangiopathy (TMA) (and thrombotic thrombocytopenic purpura [TTP]) include the following: Anemia: Anemia[emedicine.medscape.com]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[medical-dictionary.thefreedictionary.com] KEYWORDS: Cerebral microbleeds; MRI; ischemic stroke; thrombotic thrombocytopenic purpura[ncbi.nlm.nih.gov] […] hemolytic anemia Often severe with Hb 7-9g/dl; severity not related to other organ system dysfunction Negative Coombs' test Smear shows signs of microangiopahy: helmet & burr[faculty.washington.edu]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] Additional laboratory tests should include bilirubin, haptoglobin, fibrinogen, lactate dehydrogenase, prothrombin time (PT), serum electrolytes, creatinine, blood urea nitrogen[symptoma.com] The similarity of the mother's illness to thrombotic thrombocytopenic purpura and of the daughter's to adult hemolytic uremic syndrome suggests that these diseases are variants[ncbi.nlm.nih.gov]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] These substances, which include blood urea nitrogen and creatinine, increase in the blood if the kidneys have been damaged.[cigna.com] thrombocytopenic purpura and hemolytic uremic syndrome during her second pregnancy, before the correct diagnosis of atypical hemolytic uremic syndrome was recognized in the[ncbi.nlm.nih.gov]

  • Renal Cell Carcinoma

    Ryan P Theis, Suzanne M Dolwick Grieb, Deborah Burr, Tariq Siddiqui and Nabih R Asal, Smoking, environmental tobacco smoke, and risk of renal cell cancer: a population-based[doi.org] Thrombotic microangiopathy (TMA) including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS).[sutent.com] Thrombotic Microangiopathy (TMA): TMA, including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), has been reported in clinical trials of VOTRIENT[hcp.novartis.com]

  • Granulomatosis with Polyangiitis

    A peripheral blood smear may show schistocytes and burr cells. Leukocytosis is also common, with a neutrophil predominance.[emedicine.medscape.com] microangiopathy M31.2 Lethal midline granuloma M31.3 Wegener's granulomatosis M31.30 …… without renal involvement M31.31 …… with renal involvement M31.4 Aortic arch syndrome[icd10data.com] Elevated blood urea nitrogen (BUN) and creatinine levels may signal renal involvement. Hypoalbuminemia may be present.[emedicine.medscape.com]

  • Nodular Glomerulosclerosis

    Such cells, called burr cells or echinocytes, are readily distinguishable from irregularly spiculated acanthocytes Acanthocytosis.[aippg.net] ; as a result, serum creatinine and urea nitrogen levels are slightly reduced.[medical-dictionary.thefreedictionary.com] microangiopathies.[ncbi.nlm.nih.gov]

  • Eclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] thrombocytopenic purpura.[emedicine.com] The differential diagnosis in these cases should include thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and exacerbation of systemic lupus.[glowm.com]

  • Post-Infectious Glomerulonephritis

    Laboratory evaluation revealed micro-angiopathic anaemia with burr cells, thrombocytopenia, elevated lactic dehydrogenase and low complement C3.[ncbi.nlm.nih.gov] PRES has several etiologies, hypertensive encephalopathy, acute or chronic renal diseases, thrombotic thrombocytopenic purpura, hemolytic and uremic syndrome, eclampsia, vasculitis[bmcresnotes.biomedcentral.com] Blood chemistries reveal increased blood urea nitrogen, increased serum creatinine, increased serum lipids, and decreased serum albumin. ASO titers are positive.[medical-dictionary.thefreedictionary.com]

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