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18 Possible Causes for Blood Urea Nitrogen Increased, Severe Peripheral Motor Neuropathy

  • Renal Impairment

    Blood urea nitrogen and creatinine increased in 1 patient. B-ultrasound revealed bilaterally enlarged kidneys in 3 patients.[ncbi.nlm.nih.gov] , peripheral sensory and motor neuropathies, muscle cramps, hyperreflexia, restless legs syndrome, and seizures (usually the result of hypertensive or metabolic encephalopathy[merckmanuals.com] Levels of ApoA4 were positively correlated with blood urea nitrogen and creatine, but negatively correlated with serum protein and albumin.[ncbi.nlm.nih.gov]

  • Chronic Kidney Insufficiency

    There may also be an increase of acid in the blood. Blood urea nitrogen test Blood urea nitrogen can become elevated when your kidneys start to fail.[healthline.com] , peripheral sensory and motor neuropathies, muscle cramps, hyperreflexia, restless legs syndrome, and seizures (usually the result of hypertensive or metabolic encephalopathy[merckmanuals.com] With more severe renal disease (eg, estimated glomerular filtration rate [eGFR] 15 mL/min/1.73 m 2 ), neuromuscular symptoms may be present, including coarse muscular twitches[merckmanuals.com]

  • Kidney Disease

    Under 6.05B2, the peripheral neuropathy must be a severe impairment. (See §§ 404.1520(c), 404.1521, 416.920(c), and 416.921 of this chapter.)[ssa.gov] The resulting neuropathy may affect peripheral motor or sensory nerves, or both, causing pain, numbness, tingling, and muscle weakness in various parts of the body.[ssa.gov]

  • Cryoimmunoglobulinemic Syndrome

    In a minority of cases the peripheral neuropathy may be complicated by severe sensory-motor manifestations, which usually appeared abruptly, often as asymmetric mononeuritis[ojrd.biomedcentral.com] The patient quality of life may be severely compromised because of the chronicity of these symptoms along with their scarce sensibility to therapeutic attempts.[ojrd.biomedcentral.com]

  • Myeloma-associated Amyloidosis

    […] focal intrahepatic mass), peripheral nervous system (painful sensory neuropathy followed by motor deficits, autonomic neuropathy and CTS) and skin [ 1 , 9 , 10 ].[academic.oup.com] […] cholestasis, portal hypertension, intractable ascites and peripheral edema, subacute or fulminant hepatic failure, hepatic encephalopathy, spontaneous hepatic rupture and[academic.oup.com] […] involvement includes heart (50% usually restrictive cardiomyopathy), kidney (33%), gastrointestinal system (involvement from mouth to anus), liver (hepatomegaly and rarely severe[academic.oup.com]

  • Uremic Neuropathy

    […] to assess the severity of symptoms and disability caused by peripheral neuropathy.[ejnpn.eg.net] Results Of the 27 patients, 70.4% had phrenic motor neuropathy, 33.4% had median motor neuropathy, 48.2% had median sensory neuropathy, 40.8% had peroneal motor neuropathy[ejnpn.eg.net] All patients and controls were subjected to history taking, neurological examination, laboratory tests, neurophysiological study of phrenic and peripheral nerves, and scales[ejnpn.eg.net]

  • Rocky Mountain Spotted Fever

    Long-term neurologic sequelae of RMSF include cognitive impairment; paraparesis; hearing loss; blindness; peripheral neuropathy; bowel and bladder incontinence; cerebellar[doi.org] , vestibular, and motor dysfunction; and speech disorders ( 7, 110, 121 – 124 ).[doi.org] These complications are observed most frequently in persons recovering from severe, life-threatening disease, often after lengthy hospitalizations, and are most likely the[doi.org]

  • Neuropathy

    Traumas, such as from motor vehicle accidents, falls or sports injuries, can sever or damage peripheral nerves.[mayoclinic.org] Adequate hydration can also be monitored by blood urea nitrogen levels. Lower extremity exercises are encouraged to increase muscle tone and promote venous return.[ncbi.nlm.nih.gov] Disorders such as Charcot-Marie-Tooth disease are hereditary types of neuropathy. Trauma or pressure on the nerve.[mayoclinic.org]

  • Autonomic Neuropathy

    Adequate hydration can also be monitored by blood urea nitrogen levels. Lower extremity exercises are encouraged to increase muscle tone and promote venous return.[ojrd.biomedcentral.com] […] and autonomic neuropathy.[ncbi.nlm.nih.gov] Diabetic autonomic neuropathy is a subgroup of diabetic neuropathy, a group of nerve diseases affecting the peripheral nerves outside the brain and spinal cord.[columbianeurology.org]

  • Chronic Kidney Disease

    HCT (MD 2.00%, 95% Cl -0.85 to 4.85).However, oxymetholone was not found to reduce blood urea nitrogen (BUN), serum creatinine (SCr), cholesterol, or triglycerides; or increase[ncbi.nlm.nih.gov] , peripheral sensory and motor neuropathies, muscle cramps, hyperreflexia, restless legs syndrome, and seizures (usually the result of hypertensive or metabolic encephalopathy[merckmanuals.com] There may also be an increase of acid in the blood. Blood urea nitrogen test Blood urea nitrogen can become elevated when your kidneys start to fail.[healthline.com]

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