Blue Sclera Causes & Reasons

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Blue Sclera Symptom Checker: Possible causes include Iron Deficiency Anemia. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Iron Deficiency Anemia

INTRODUCTION Iron deficiency anemia (IDA) is a common complication in routine clinical practice that frequently originates in the gastrointestinal (GI) tract[ 1 - 3 ]. Patients with IDA are therefore often referred to gastroenterologists for further examination and/or treatment. IDA associated with GI disorders can[…] [dx.doi.org]

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Marfan Syndrome

Keywords: Aortic root dilatation, blue sclera, enophthalmos, Neonatal Marfan Syndrome How to cite this article: Bhutia E, Kumar P, Kishore S, Yadav DK. [jcnonweb.com]

sclera, Chiari malformations, and club feet. [acc.org]

LDS patients may also have widely spaced eyes, cleft palate, blue sclerae, and type 1 Chiari malformations (in which a portion of the cerebellum descends out of the skull [forgottendiseases.org]

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Rheumatoid Arthritis

Please log in to edit this article. Edit Synonym: chronic polyarthritis (CP) Lay term: rheumatism German : Rheumatoide Arthritis 1 Definition Rheumatoid arthritis is a chronic inflammation system disease, which occurs in the interior skin ( synovium ), of a joint and causes a clinical picture of a polyarthritis.[…] [flexikon.doccheck.com]

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Osteogenesis Imperfecta

Blue sclerae were present in 93.4% of patients, dentinogenesis imperfecta was observed in 27.6% of patients, and wormian bones in 29.4% of them. [ncbi.nlm.nih.gov]

The patient's mother also had blue sclera and a history of frequent fracture episodes until the age of 15 years. [ncbi.nlm.nih.gov]

sclerae, Adair-Dighton syndrome, Mild osteogenesis imperfecta, Non-deforming osteogenesis imperfecta, Van der Hoeve syndrome, Classic non-deforming OI with blue sclerae Osteogenesis [rarediseases.info.nih.gov]

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Hallermann-Streiff Syndrome

Common ocular manifestations include microphthalmia, bilateral congenital cataracts with spontaneous rupture and reabsorption, blue sclera and iris atrophy. [aaopt.org]

Blue sclerae, nystagmus, strabismus, and glaucoma are present in 10 to 30% of patients. [disorders.eyes.arizona.edu]

Ophthalmic features are microphthalmia, congenital cataracts, blue sclerae and nystagmus. [jpgmonline.com]

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Osteogenesis Imperfecta Type 15

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. [malacards.org]

sclerae and wormian bones but without fractures Osteopenic Nonfracture Syndrome osteoporosis-pseudoglioma syndrome [rgd.mcw.edu]

sclerae, death for respiratory insufficiency and pneumonias. [iofbonehealth.org]

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Crouzon Syndrome

Other associations are aniridia, blue sclera, cataract, coloboma, ectopia lentis and optic nerve hypoplasia. No medical treatment exists for craniosynostosis. [casereports.bmj.com]

There also have been rare occurances of nystagmus, iris coloboma, aniridia, anisocoria, microcornea, megalocornea, cataract, ectopia lentis, blue sclera, glaucoma and luxation [scialert.net]

There rarely may occur nystagmus, coloboma of the iris, anisocoria, microcornea or megalocornea, cataract, blue sclerae, glaucoma and globe luxation (6). [arquivosdeorl.org.br]

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Pseudoxanthoma Elasticum

• Other ocular findings: blue sclera Classification • Dominant type 1, which contains cutaneous changes and the skin becomes thin, delicate and bruises easily. [eyewiki.aao.org]

• Dominant type 2, which is characterised by atypical, yellowish, flatter skin papules than in dominant type 1, skin hyperelasticity, mild angioid streaks and blue sclera [eyewiki.aao.org]

sclera: • Osteogenesis imperfecta • Ehlers-Danlos syndrome (type VI) • Cornea plana, peripheral sclerocornea, buphthalmos, keratoconus, keratoglobus, high myopia, ciliary [eyewiki.aao.org]

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Brittle Cornea Syndrome Type 1

A syndrome of red hair, blue sclera, and brittle cornea with recurrent spontaneous perforations is presented in 2 siblings of a Tunisian Jewish family. [ncbi.nlm.nih.gov]

Brittle cornea, blue sclera, and red hair syndrome (the brittle cornea syndrome). [bjo.bmj.com]

We report a patient with the characteristic features of the brittle cornea syndrome, a rare, autosomal recessively inherited disorder, namely brittle corneae, blue sclerae [ncbi.nlm.nih.gov]

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Brittle Cornea Syndrome Type 2

Brittle cornea, blue sclera, and red hair syndrome (the brittle cornea syndrome). [bjo.bmj.com]

sclerae, hyperelasticity of the skin without excessive fragility, and hypermobility of the joints. [zora.uzh.ch]

Arkin W (1964) Blue scleras with keratoglobus. Am J Ophthalmol 58: 678–682 Google Scholar 2. Attiah MAH, Sobhy Bey M (1931) Blue sclerotis. [link.springer.com]

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Dermatosparaxis

He subsequently exhibited marked skin fragility, blue sclerae, joint laxity, increased bruisability, and growth retardation. [ncbi.nlm.nih.gov]

Conclusions: The newly recognized phenotype of Ehlers-Danlos VII-C is a distinct connective tissue disorder characterized by marked skin fragility and laxity, blue sclerae [jamanetwork.com]

The newly recognized phenotype of Ehlers-Danlos VII-C is a distinct connective tissue disorder characterized by marked skin fragility and laxity, blue sclerae, increased bruisability [ncbi.nlm.nih.gov]

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Goldberg-Shprintzen Syndrome

Dysmorphological evaluation at 5 years (fig 2 ) showed high arched eyebrows, dense curled eyelashes, a broad nasal bridge, blue sclerae, large corneae (corneal diameter 13.5 [jmg.bmj.com]

sclerae Exotropia Craniosynostosis Cervical spine instability Talipes equinovarus Soft and velvety skin Translucent skin Easy bruising Generalized arterial tortuosity and [medicinman.cz]

[…] dissection Dolichostenomelia Absent (ectopia lentis) Hypertelorism Broad or bifid uvula Cleft palate Learning disability (rare) Hydrocephalus (rare) Chiari I malformation Blue [medicinman.cz]

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Keratoglobus

Patients with keratoglobus and blue sclera as part of a generalized connective tissue disorder are at a high risk of developing corneal perforations either spontaneously or [ncbi.nlm.nih.gov]

Five patients from two families had similar features including keratoglobus, blue scleras, hyperextensibility of the hand, wrist, and ankle joints, sensorineural conduction [ncbi.nlm.nih.gov]

Marshall-Stickler syndrome may exist in the differential diagnosis of keratoglobus with blue sclera. [ncbi.nlm.nih.gov]

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Scleromalacia

[…] of the sclera in her left eye. [mejfm.com]

CONGENITAL MELANOSIS OCULI: Melanosis oculi (ocular melanocytosis) is congential blue nevus of the episclera and sclera associated with increased pigmentation of the uveal [visioncareindia.com]

Scleromalacia perforans is a rare form of anterior scleritis which readily presents as a blackish blue hue visible through a thin sclera [ 3 ]. [ncbi.nlm.nih.gov]

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Marshall-Smith Syndrome

sclerae, depressed nasal bridge, and micrognathia. [ncbi.nlm.nih.gov]

Clinical description The disorder associates several dysmorphic signs, including prominent forehead, bulging eyes, blue sclerae, anterversed nostrils and micrognathia. [orpha.net]

[…] accelerated skeletal maturation, relative failure to thrive, respiratory difficulties, mental retardation, and unusual facies, including prominent forehead, shallow orbits, blue [ncbi.nlm.nih.gov]

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Ehlers-Danlos Syndrome

sclerae, small jaw, hypertrichosis Dominant COL1A1, COL1A2 Arthrochalasia, type VII A/B (Exon 6 COL1A1/2 ) Dermatosparaxis Type (EDS type VIIC) Soft and very thin, fragile [uwcpdx.org]

Other eye symptoms may include nearsightedness ( myopia ), a blueish tint in the white part of the eyes (blue sclera), and retinal detachment. [rarediseases.info.nih.gov]

Blue sclera. Thin, translucient, fragile skin. Easy bruising. Pes planus. Recurrent joint dislocation.Chronic joint pains. Easy brushing. Varicose veins. [laeknabladid.is]

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Orthostatic Syncope

Sclerae are blue. The skull is soft and, when palpated, feels like a bag of bones. [msdmanuals.com]

Blue sclerae is an important sign caused by scleral thinness allowing the pigmented coat of the choroid to become visible. [patient.info]

Patients with this condition have had short stature, blue or white sclerae, and normal hearing. [emedicine.medscape.com]

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Osteogenesis Imperfecta Type 2

The disease is characterized by short limb dwarfism, thin skin, soft skull, unusually large fontanels (soft spots), blue sclerae (whites of the eyes, small nose, low nasal [medicinenet.com]

On exam, her sclera are blue. [medbullets.com]

Affected individuals exhibit short limb dwarfism, thin skin, soft skull, unusually large fontanels (soft spots), blue sclera, whites of the eyes, small nose, low nasal bridge [writerightmel.wordpress.com]

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Osteogenesis Imperfecta Type 13

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. [malacards.org]

On examination, she had a blue-grey sclera, small thorax, relatively large cranium, and disproportionately short and curved limbs. [kenkyugroup.org]

sclera, deafness) Blue sclera Q13.5 ICD-10-CM Diagnosis Code Q13.5 Blue sclera 2016 2017 2018 2019 Billable/Specific Code POA Exempt with fragility of bone and deafness Q78.0 [icd10data.com]

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Osteogenesis Imperfecta Type 16

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI16 is a severe form. [malacards.org]

Short stature, blue sclerae and dentinogenesis imperfecta (DI) Sometimes, the evaluation for OI in childhood is prompted by recognition of blue sclerae, conductive hearing [nature.com]

[…] in the perinatal period Numerous fractures and severe bone deformity Length and weight SGA Head large for body size Usually blue-gray sclera Markedly reduced ossification [en.wikibooks.org]

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Osteogenesis Imperfecta Type 5

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. [malacards.org]

Diagnosis - Osteogenesis imperfecta- type 5 Family history and characteristic features, such as blue sclerae or deafness, establish the diagnosis. [checkorphan.org]

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Osteogenesis Imperfecta Type 3

[…] in the perinatal period Numerous fractures and severe bone deformity Length and weight SGA Head large for body size Usually blue-gray sclera Markedly reduced ossification [en.wikibooks.org]

The classic symptoms include: blue tint to the whites of the eyes (blue sclera) multiple bone fractures - the frequency of fractures may increase in adolescence early hearing [focusondisability.org.uk]

Diagnosis - Osteogenesis imperfecta- type 3 Family history and characteristic features, such as blue sclerae or deafness, establish the diagnosis. [checkorphan.org]

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Cole-Carpenter Syndrome

In addition, these patients also had proptosis, blue sclerae, hydrocephalus, and a distinct facial gestalt. They were reported to be of normal intelligence. [ncbi.nlm.nih.gov]

sclera. [dovemed.com]

sclera, in association with growth failure, craniosynostosis, hydrocephalus, ocular proptosis, and distinctive facial features (e.g. frontal bossing, midface hypoplasia, [malacards.org]

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Bruck Syndrome

He did not have blue sclerae, dentinogenesis imperfecta, or hearing loss. [ncbi.nlm.nih.gov]

In addition to defective type I collagen, manifesting as bone fragility, osteoporosis, and blue sclera, Bruck syndrome is additionally characterized by arthrogryposis with [ochsnerjournal.org]

A 10-year-old girl was referred with blue sclera, osteopenia, poorly-healing fragility fractures, Wormian skull bones, cleft soft palate, congenital fusion of cervical vertebrae [profiles.wustl.edu]

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Wiedemann-Rautenstrauch Syndrome

Widened middle and proximal phalanges, failure to thrive, craniofacial abnormalities (small face, prominent eyes, blue sclera, flat nose with anteverted nares, choanal atresia [icd10data.com]

sclerae Whites of eyes are a bluish-gray color 0000592 Congenital malformation of the left heart 0045017 Dysplastic pulmonary valve 0005164 Hyperthyroidism Overactive thyroid [rarediseases.info.nih.gov]

He had alo-pecia of eyebrows and eyelashes, blue scleras, low-set androtated ears, thin lips, and down-slanting mouth angles.Four teeth were observed at delivery, 2 yellowish [docslide.com.br]

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Laron Syndrome

It is characterized by short stature, blue sclerae, hip degeneration, and delayed bone age. [accessanesthesiology.mhmedical.com]

Patients occasionally have blue sclera and hip degeneration. Etiology The disease is due to mutations in the GHR gene (5p14-p12). [orpha.net]

Delayed nail growth and blue sclerae may also be present. [symptoma.com]

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Rathbun Syndrome

The Rathbun syndrome, also known as hypophosphatasia, is a congenital, autosomal recessive disease caused by defective encoding of tissue-nonspecific alkaline phosphatase leading to peripheral (serum and tissue) deficiency of this enzyme. The illness has several degrees of severity, causing symptoms at various[…] [symptoma.com]

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Kabuki Syndrome

sclerae, large dysplastic ears, lower lip pits), persistent fetal fingertip pads, short stature, heart defects (interventricular defect and aortic coarctation), unilateral [ncbi.nlm.nih.gov]

Several typical facial features such as large dysplastic ears, arched eyebrows with sparse lateral third, blue sclerae, a flat nasal tip with a broad nasal root, and a thin [ncbi.nlm.nih.gov]

[…] among patients but may include: Long eyelashes, depressed nasal tip, atypical fingerprints, ear deformity (macrotia or microtia), hypotonia, joint hyperflexibility, ptosis, blue [en.wikipedia.org]

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Onychia

Sclerae are blue. The skull is soft and, when palpated, feels like a bag of bones. [msdmanuals.com]

Blue sclerae is an important sign caused by scleral thinness allowing the pigmented coat of the choroid to become visible. [patient.info]

Patients with this condition have had short stature, blue or white sclerae, and normal hearing. [emedicine.medscape.com]

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Chondrodystrophy

We have described a previously unrecognized chondrodystrophy characterized by short-limbed dwarfism, blue sclera, severe cardiopulmonary problems, and failure of postnatal [ncbi.nlm.nih.gov]

In classic non-deforming osteogenesis Imperfecta with blue sclerae or common variable osteogenesis Imperfecta with normal sclerae, nearly 60% of cases are de novo. [en.wikipedia.org]

Classic non-deforming OI with blue sclerae (previously OI type I) is characterized by blue sclerae and normal stature. [ncbi.nlm.nih.gov]

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