Blue Sclera Causes & Reasons

Neu Starten

Ad Html Headline Ad Text Headline

Ad Label Ad Html Description Ad Text Description

Determine your risk of now. Restart test

Caution! In case of an emergency:

Seek emergency care

Caution! In case of an emergency: Seek emergency care

Hi, I'm Symptoma.

Blue Sclera Symptom Checker: Possible causes include Iron Deficiency Anemia. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

For full functionality of this site it is necessary to enable JavaScript.

How to enable JavaScript?

Possible Causes

Iron Deficiency Anemia

INTRODUCTION Iron deficiency anemia (IDA) is a common complication in routine clinical practice that frequently originates in the gastrointestinal (GI) tract[ 1 - 3 ]. Patients with IDA are therefore often referred to gastroenterologists for further examination and/or treatment. IDA associated with GI disorders can[…] [dx.doi.org]

Show info

Marfan Syndrome

Keywords: Aortic root dilatation, blue sclera, enophthalmos, Neonatal Marfan Syndrome How to cite this article: Bhutia E, Kumar P, Kishore S, Yadav DK. [jcnonweb.com]

sclera, Chiari malformations, and club feet. [acc.org]

LDS patients may also have widely spaced eyes, cleft palate, blue sclerae, and type 1 Chiari malformations (in which a portion of the cerebellum descends out of the skull [forgottendiseases.org]

Show info

Rheumatoid Arthritis

Please log in to edit this article. Edit Synonym: chronic polyarthritis (CP) Lay term: rheumatism German : Rheumatoide Arthritis 1 Definition Rheumatoid arthritis is a chronic inflammation system disease, which occurs in the interior skin ( synovium ), of a joint and causes a clinical picture of a polyarthritis.[…] [flexikon.doccheck.com]

Show info

Osteogenesis Imperfecta

Blue sclerae were present in 93.4% of patients, dentinogenesis imperfecta was observed in 27.6% of patients, and wormian bones in 29.4% of them. [ncbi.nlm.nih.gov]

The patient's mother also had blue sclera and a history of frequent fracture episodes until the age of 15 years. [ncbi.nlm.nih.gov]

sclerae, Adair-Dighton syndrome, Mild osteogenesis imperfecta, Non-deforming osteogenesis imperfecta, Van der Hoeve syndrome, Classic non-deforming OI with blue sclerae Osteogenesis [rarediseases.info.nih.gov]

Show info

Hallermann-Streiff Syndrome

Common ocular manifestations include microphthalmia, bilateral congenital cataracts with spontaneous rupture and reabsorption, blue sclera and iris atrophy. [aaopt.org]

Blue sclerae, nystagmus, strabismus, and glaucoma are present in 10 to 30% of patients. [disorders.eyes.arizona.edu]

Ophthalmic features are microphthalmia, congenital cataracts, blue sclerae and nystagmus. [jpgmonline.com]

Show info

Osteogenesis Imperfecta Type 15

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. [malacards.org]

sclerae and wormian bones but without fractures Osteopenic Nonfracture Syndrome osteoporosis-pseudoglioma syndrome [rgd.mcw.edu]

sclerae, death for respiratory insufficiency and pneumonias. [iofbonehealth.org]

Show info

Crouzon Syndrome

Other associations are aniridia, blue sclera, cataract, coloboma, ectopia lentis and optic nerve hypoplasia. No medical treatment exists for craniosynostosis. [casereports.bmj.com]

There also have been rare occurances of nystagmus, iris coloboma, aniridia, anisocoria, microcornea, megalocornea, cataract, ectopia lentis, blue sclera, glaucoma and luxation [scialert.net]

There rarely may occur nystagmus, coloboma of the iris, anisocoria, microcornea or megalocornea, cataract, blue sclerae, glaucoma and globe luxation (6). [arquivosdeorl.org.br]

Show info

Pseudoxanthoma Elasticum

• Other ocular findings: blue sclera Classification • Dominant type 1, which contains cutaneous changes and the skin becomes thin, delicate and bruises easily. [eyewiki.aao.org]

• Dominant type 2, which is characterised by atypical, yellowish, flatter skin papules than in dominant type 1, skin hyperelasticity, mild angioid streaks and blue sclera [eyewiki.aao.org]

sclera: • Osteogenesis imperfecta • Ehlers-Danlos syndrome (type VI) • Cornea plana, peripheral sclerocornea, buphthalmos, keratoconus, keratoglobus, high myopia, ciliary [eyewiki.aao.org]

Show info

Brittle Cornea Syndrome Type 1

A syndrome of red hair, blue sclera, and brittle cornea with recurrent spontaneous perforations is presented in 2 siblings of a Tunisian Jewish family. [ncbi.nlm.nih.gov]

Brittle cornea, blue sclera, and red hair syndrome (the brittle cornea syndrome). [bjo.bmj.com]

We report a patient with the characteristic features of the brittle cornea syndrome, a rare, autosomal recessively inherited disorder, namely brittle corneae, blue sclerae [ncbi.nlm.nih.gov]

Show info

Brittle Cornea Syndrome Type 2

Brittle cornea, blue sclera, and red hair syndrome (the brittle cornea syndrome). [bjo.bmj.com]

sclerae, hyperelasticity of the skin without excessive fragility, and hypermobility of the joints. [zora.uzh.ch]

Arkin W (1964) Blue scleras with keratoglobus. Am J Ophthalmol 58: 678–682 Google Scholar 2. Attiah MAH, Sobhy Bey M (1931) Blue sclerotis. [link.springer.com]

Show info

Dermatosparaxis

He subsequently exhibited marked skin fragility, blue sclerae, joint laxity, increased bruisability, and growth retardation. [ncbi.nlm.nih.gov]

Conclusions: The newly recognized phenotype of Ehlers-Danlos VII-C is a distinct connective tissue disorder characterized by marked skin fragility and laxity, blue sclerae [jamanetwork.com]

The newly recognized phenotype of Ehlers-Danlos VII-C is a distinct connective tissue disorder characterized by marked skin fragility and laxity, blue sclerae, increased bruisability [ncbi.nlm.nih.gov]

Show info

Goldberg-Shprintzen Syndrome

Dysmorphological evaluation at 5 years (fig 2 ) showed high arched eyebrows, dense curled eyelashes, a broad nasal bridge, blue sclerae, large corneae (corneal diameter 13.5 [jmg.bmj.com]

sclerae Exotropia Craniosynostosis Cervical spine instability Talipes equinovarus Soft and velvety skin Translucent skin Easy bruising Generalized arterial tortuosity and [medicinman.cz]

[…] dissection Dolichostenomelia Absent (ectopia lentis) Hypertelorism Broad or bifid uvula Cleft palate Learning disability (rare) Hydrocephalus (rare) Chiari I malformation Blue [medicinman.cz]

Show info

Keratoglobus

Patients with keratoglobus and blue sclera as part of a generalized connective tissue disorder are at a high risk of developing corneal perforations either spontaneously or [ncbi.nlm.nih.gov]

Five patients from two families had similar features including keratoglobus, blue scleras, hyperextensibility of the hand, wrist, and ankle joints, sensorineural conduction [ncbi.nlm.nih.gov]

Marshall-Stickler syndrome may exist in the differential diagnosis of keratoglobus with blue sclera. [ncbi.nlm.nih.gov]

Show info

Scleromalacia

[…] of the sclera in her left eye. [mejfm.com]

CONGENITAL MELANOSIS OCULI: Melanosis oculi (ocular melanocytosis) is congential blue nevus of the episclera and sclera associated with increased pigmentation of the uveal [visioncareindia.com]

Scleromalacia perforans is a rare form of anterior scleritis which readily presents as a blackish blue hue visible through a thin sclera [ 3 ]. [ncbi.nlm.nih.gov]

Show info

Marshall-Smith Syndrome

sclerae, depressed nasal bridge, and micrognathia. [ncbi.nlm.nih.gov]

Clinical description The disorder associates several dysmorphic signs, including prominent forehead, bulging eyes, blue sclerae, anterversed nostrils and micrognathia. [orpha.net]

[…] accelerated skeletal maturation, relative failure to thrive, respiratory difficulties, mental retardation, and unusual facies, including prominent forehead, shallow orbits, blue [ncbi.nlm.nih.gov]

Show info

Ehlers-Danlos Syndrome

sclerae, small jaw, hypertrichosis Dominant COL1A1, COL1A2 Arthrochalasia, type VII A/B (Exon 6 COL1A1/2 ) Dermatosparaxis Type (EDS type VIIC) Soft and very thin, fragile [uwcpdx.org]

Other eye symptoms may include nearsightedness ( myopia ), a blueish tint in the white part of the eyes (blue sclera), and retinal detachment. [rarediseases.info.nih.gov]

Blue sclera. Thin, translucient, fragile skin. Easy bruising. Pes planus. Recurrent joint dislocation.Chronic joint pains. Easy brushing. Varicose veins. [laeknabladid.is]

Show info

Orthostatic Syncope

Sclerae are blue. The skull is soft and, when palpated, feels like a bag of bones. [msdmanuals.com]

Blue sclerae is an important sign caused by scleral thinness allowing the pigmented coat of the choroid to become visible. [patient.info]

Patients with this condition have had short stature, blue or white sclerae, and normal hearing. [emedicine.medscape.com]

Show info

Osteogenesis Imperfecta Type 2

The disease is characterized by short limb dwarfism, thin skin, soft skull, unusually large fontanels (soft spots), blue sclerae (whites of the eyes, small nose, low nasal [medicinenet.com]

On exam, her sclera are blue. [medbullets.com]

Affected individuals exhibit short limb dwarfism, thin skin, soft skull, unusually large fontanels (soft spots), blue sclera, whites of the eyes, small nose, low nasal bridge [writerightmel.wordpress.com]

Show info

Osteogenesis Imperfecta Type 13

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. [malacards.org]

On examination, she had a blue-grey sclera, small thorax, relatively large cranium, and disproportionately short and curved limbs. [kenkyugroup.org]

sclera, deafness) Blue sclera Q13.5 ICD-10-CM Diagnosis Code Q13.5 Blue sclera 2016 2017 2018 2019 Billable/Specific Code POA Exempt with fragility of bone and deafness Q78.0 [icd10data.com]

Show info

Osteogenesis Imperfecta Type 16

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI16 is a severe form. [malacards.org]

Short stature, blue sclerae and dentinogenesis imperfecta (DI) Sometimes, the evaluation for OI in childhood is prompted by recognition of blue sclerae, conductive hearing [nature.com]

[…] in the perinatal period Numerous fractures and severe bone deformity Length and weight SGA Head large for body size Usually blue-gray sclera Markedly reduced ossification [en.wikibooks.org]

Show info

Osteogenesis Imperfecta Type 5

Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. [malacards.org]

Diagnosis - Osteogenesis imperfecta- type 5 Family history and characteristic features, such as blue sclerae or deafness, establish the diagnosis. [checkorphan.org]

Show info

Osteogenesis Imperfecta Type 3

[…] in the perinatal period Numerous fractures and severe bone deformity Length and weight SGA Head large for body size Usually blue-gray sclera Markedly reduced ossification [en.wikibooks.org]

The classic symptoms include: blue tint to the whites of the eyes (blue sclera) multiple bone fractures - the frequency of fractures may increase in adolescence early hearing [focusondisability.org.uk]

Diagnosis - Osteogenesis imperfecta- type 3 Family history and characteristic features, such as blue sclerae or deafness, establish the diagnosis. [checkorphan.org]

Show info

Cole-Carpenter Syndrome

In addition, these patients also had proptosis, blue sclerae, hydrocephalus, and a distinct facial gestalt. They were reported to be of normal intelligence. [ncbi.nlm.nih.gov]

sclera. [dovemed.com]

sclera, in association with growth failure, craniosynostosis, hydrocephalus, ocular proptosis, and distinctive facial features (e.g. frontal bossing, midface hypoplasia, [malacards.org]

Show info

Bruck Syndrome

He did not have blue sclerae, dentinogenesis imperfecta, or hearing loss. [ncbi.nlm.nih.gov]

In addition to defective type I collagen, manifesting as bone fragility, osteoporosis, and blue sclera, Bruck syndrome is additionally characterized by arthrogryposis with [ochsnerjournal.org]

A 10-year-old girl was referred with blue sclera, osteopenia, poorly-healing fragility fractures, Wormian skull bones, cleft soft palate, congenital fusion of cervical vertebrae [profiles.wustl.edu]

Show info

Wiedemann-Rautenstrauch Syndrome

Widened middle and proximal phalanges, failure to thrive, craniofacial abnormalities (small face, prominent eyes, blue sclera, flat nose with anteverted nares, choanal atresia [icd10data.com]

sclerae Whites of eyes are a bluish-gray color 0000592 Congenital malformation of the left heart 0045017 Dysplastic pulmonary valve 0005164 Hyperthyroidism Overactive thyroid [rarediseases.info.nih.gov]

He had alo-pecia of eyebrows and eyelashes, blue scleras, low-set androtated ears, thin lips, and down-slanting mouth angles.Four teeth were observed at delivery, 2 yellowish [docslide.com.br]

Show info

Laron Syndrome

It is characterized by short stature, blue sclerae, hip degeneration, and delayed bone age. [accessanesthesiology.mhmedical.com]

Patients occasionally have blue sclera and hip degeneration. Etiology The disease is due to mutations in the GHR gene (5p14-p12). [orpha.net]

Delayed nail growth and blue sclerae may also be present. [symptoma.com]

Show info

Rathbun Syndrome

The Rathbun syndrome, also known as hypophosphatasia, is a congenital, autosomal recessive disease caused by defective encoding of tissue-nonspecific alkaline phosphatase leading to peripheral (serum and tissue) deficiency of this enzyme. The illness has several degrees of severity, causing symptoms at various[…] [symptoma.com]

Show info

Kabuki Syndrome

sclerae, large dysplastic ears, lower lip pits), persistent fetal fingertip pads, short stature, heart defects (interventricular defect and aortic coarctation), unilateral [ncbi.nlm.nih.gov]

Several typical facial features such as large dysplastic ears, arched eyebrows with sparse lateral third, blue sclerae, a flat nasal tip with a broad nasal root, and a thin [ncbi.nlm.nih.gov]

[…] among patients but may include: Long eyelashes, depressed nasal tip, atypical fingerprints, ear deformity (macrotia or microtia), hypotonia, joint hyperflexibility, ptosis, blue [en.wikipedia.org]

Show info

Onychia

Sclerae are blue. The skull is soft and, when palpated, feels like a bag of bones. [msdmanuals.com]

Blue sclerae is an important sign caused by scleral thinness allowing the pigmented coat of the choroid to become visible. [patient.info]

Patients with this condition have had short stature, blue or white sclerae, and normal hearing. [emedicine.medscape.com]

Show info

Chondrodystrophy

We have described a previously unrecognized chondrodystrophy characterized by short-limbed dwarfism, blue sclera, severe cardiopulmonary problems, and failure of postnatal [ncbi.nlm.nih.gov]

In classic non-deforming osteogenesis Imperfecta with blue sclerae or common variable osteogenesis Imperfecta with normal sclerae, nearly 60% of cases are de novo. [en.wikipedia.org]

Classic non-deforming OI with blue sclerae (previously OI type I) is characterized by blue sclerae and normal stature. [ncbi.nlm.nih.gov]

Show info

⚕ Symptoma®️ is a digital health assistant but no replacement for the opinion and judgement of medical professionals. By using this website you fully understand and accept that it shall not be used as a diagnostic system for decision-making. It absolutely must not be used to obtain, replace or overrule a clinical diagnosis by a healthcare professional. It is always for the medical professional to make the final diagnosis. The medical information provided on this website is of a general nature and can not substitute for the advice of a medical professional (for example, a qualified doctor or physician)! Information from the internet could and should NOT be solely used to offer or render a medical opinion or otherwise engage in the practice of medicine.