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283 Possible Causes for Bone Marrow Biopsy Abnormal, Increased Susceptibility to Infections

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[] Patients included were diagnosed with primary hypocellular RC between 1 July 1998 and 31 December 2006 after central reference review of bone marrow biopsies.[] An annual bone marrow biopsy has to be performed for surveillance of the acquisition of cytogenetic abnormalities. (5) Complications of the disease, such as sepsis or hematological[]

  • Aplastic Anemia

    A reduced number of neutrophils (a major type of white blood cell important for defense against bacterial and fungal infections) increases susceptibility to infection.[] Bone marrow biopsy shows hypocellular marrow without abnormal cells.[] A procedure that involves taking a small amount of bone marrow fluid (aspiration) and/or solid bone marrow tissue called a core biopsy, usually from the hip bones, to be examined[]

  • IgE Myeloma

    […] to infections) and platelets (increasing your susceptibility to bleeding and bruising).[] A bone marrow biopsy revealed an interstitial and nodular infiltration of abnormal plasma cells comprising 60% of nucleated cells present.[] Low white blood cell count: Symptoms include increased frequency of and susceptibility to infections.[]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    These conditions manifest in: Pallor, fatigue, reduced resistance to exercise, and dyspnea as symptoms of anemia Increased susceptibility to infections as a sign of leukopenia[]

  • Myelodysplasia

    susceptibility to infections even in the absence of neutropenia. 50 - 52 However, these defects have still not been well defined in clinical studies.[] Fluorescence in situ hybridization performed on the gingival biopsy specimen demonstrated the same del(20q) cytogenetic abnormality present in the bone marrow, confirming[] The hallmark feature of MDS is a bone marrow aspirate and biopsy that reveals heavy infiltration with abnormal-looking bone marrow cells.[]

  • Leukoerythroblastic Anemia

    The anemia causes fatigue, weakness, and paleness; the leukopenia causes increased susceptibility to infection; the thrombocytopenia causes easy bruising and bleeding.[] Biol Phys biopsy bleeding bleomycin bone marrow breast cancer cancer pain cancer patients cancer rehabilitation cancer treatment carcinoma chemotherapy chest chronic cisplatin[] Abnormal osteoclastic bone resorption Severe bone marrow failure; pancytopenia; bleeding; infection; failure to thrive; growth retardation; proptosis; blindness; deafness[]

  • Multiple Myeloma

    Both humoral and cell mediated immunities are compromised in these patients, leading to increased susceptibility to infections.[] The diagnosis is made when a large number of abnormal plasma cells are found in the patient's bone marrow. The doctor obtains this marrow through a bone biopsy.[] These late complications may result from chemotherapy and often lead to severe anemia and an increased susceptibility to infections and bleeding.[]

  • Acute Lymphoblastic Leukemia Type L1

    […] the suggestion that infection may be associated with ALL.[] Blood tests may include: Complete blood count (CBC), including white blood cell (WBC) count Platelet count Bone marrow biopsy Lumbar puncture ( spinal tap ) to check for leukemia[] Leukemic blasts may not be present on the peripheral blood smear, and only a bone marrow aspirate and/or biopsy can confirm the diagnosis in this situation.[]

  • Acute Myelocytic Leukemia

    Common to all leukemias are the tendency to bleed and the resultant anemia and increased susceptibility to infection.[] A bone marrow biopsy or a bone marrow aspiration may be done if the results of the blood tests are abnormal.[] Lowered levels of normal white blood cells increase the risk of infection.[]

  • Primary Myelofibrosis

    […] ranging from tiredness, lethargy and bloodclotting to an increased susceptibility to infections.[] The bone marrow trephine biopsy typically shows abnormal fibrosis of the marrow cavity.[] susceptibility to infection, such as pneumonia Pallor and shortness of breath due to anemia In rarer cases, a raised red blood cell volume Cutaneous myelofibrosis is a rare[]

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