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283 Possible Causes for Bone Marrow Biopsy Abnormal, Increased Susceptibility to Infections

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[rarediseases.org] Patients included were diagnosed with primary hypocellular RC between 1 July 1998 and 31 December 2006 after central reference review of bone marrow biopsies.[haematologica.org] An annual bone marrow biopsy has to be performed for surveillance of the acquisition of cytogenetic abnormalities. (5) Complications of the disease, such as sepsis or hematological[signavitae.com]

  • Aplastic Anemia

    A reduced number of neutrophils (a major type of white blood cell important for defense against bacterial and fungal infections) increases susceptibility to infection.[childrenshospital.org] Bone marrow biopsy shows hypocellular marrow without abnormal cells.[bestpractice.bmj.com] A procedure that involves taking a small amount of bone marrow fluid (aspiration) and/or solid bone marrow tissue called a core biopsy, usually from the hip bones, to be examined[stanfordchildrens.org]

  • IgE Myeloma

    […] to infections) and platelets (increasing your susceptibility to bleeding and bruising).[leukaemiaqld.org.au] A bone marrow biopsy revealed an interstitial and nodular infiltration of abnormal plasma cells comprising 60% of nucleated cells present.[ncbi.nlm.nih.gov] Low white blood cell count: Symptoms include increased frequency of and susceptibility to infections.[emedicinehealth.com]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    These conditions manifest in: Pallor, fatigue, reduced resistance to exercise, and dyspnea as symptoms of anemia Increased susceptibility to infections as a sign of leukopenia[symptoma.com]

  • Myelodysplasia

    susceptibility to infections even in the absence of neutropenia. 50 - 52 However, these defects have still not been well defined in clinical studies.[haematologica.org] Fluorescence in situ hybridization performed on the gingival biopsy specimen demonstrated the same del(20q) cytogenetic abnormality present in the bone marrow, confirming[ncbi.nlm.nih.gov] The hallmark feature of MDS is a bone marrow aspirate and biopsy that reveals heavy infiltration with abnormal-looking bone marrow cells.[ucsfhealth.org]

  • Leukoerythroblastic Anemia

    The anemia causes fatigue, weakness, and paleness; the leukopenia causes increased susceptibility to infection; the thrombocytopenia causes easy bruising and bleeding.[proz.com] Biol Phys biopsy bleeding bleomycin bone marrow breast cancer cancer pain cancer patients cancer rehabilitation cancer treatment carcinoma chemotherapy chest chronic cisplatin[books.google.com] Abnormal osteoclastic bone resorption Severe bone marrow failure; pancytopenia; bleeding; infection; failure to thrive; growth retardation; proptosis; blindness; deafness[aafp.org]

  • Multiple Myeloma

    Both humoral and cell mediated immunities are compromised in these patients, leading to increased susceptibility to infections.[ncbi.nlm.nih.gov] The diagnosis is made when a large number of abnormal plasma cells are found in the patient's bone marrow. The doctor obtains this marrow through a bone biopsy.[orthoinfo.aaos.org] These late complications may result from chemotherapy and often lead to severe anemia and an increased susceptibility to infections and bleeding.[merckmanuals.com]

  • Acute Lymphoblastic Leukemia Type L1

    […] the suggestion that infection may be associated with ALL.[bmj.com] Blood tests may include: Complete blood count (CBC), including white blood cell (WBC) count Platelet count Bone marrow biopsy Lumbar puncture ( spinal tap ) to check for leukemia[medlineplus.gov] Leukemic blasts may not be present on the peripheral blood smear, and only a bone marrow aspirate and/or biopsy can confirm the diagnosis in this situation.[clinicaladvisor.com]

  • Acute Myelocytic Leukemia

    Common to all leukemias are the tendency to bleed and the resultant anemia and increased susceptibility to infection.[medical-dictionary.thefreedictionary.com] A bone marrow biopsy or a bone marrow aspiration may be done if the results of the blood tests are abnormal.[medicinenet.com] Lowered levels of normal white blood cells increase the risk of infection.[ucsfhealth.org]

  • Primary Myelofibrosis

    […] ranging from tiredness, lethargy and bloodclotting to an increased susceptibility to infections.[aoporphan.com] The bone marrow trephine biopsy typically shows abnormal fibrosis of the marrow cavity.[leukaemia.org.au] susceptibility to infection, such as pneumonia Pallor and shortness of breath due to anemia In rarer cases, a raised red blood cell volume Cutaneous myelofibrosis is a rare[en.wikipedia.org]

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