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68 Possible Causes for Bone Marrow Biopsy Abnormal, Macrocytic Anemia, Night Sweats

  • Myelodysplasia

    Medical Importance The myelodysplastic syndromes are clonal hematopoietic disorders that commonly cause macrocytic anemia in older patients.[hematology.org] Signs of transformation to a more aggressive lymphoma include worsening constitutional symptoms (weakness, fatigue, fever, weight loss, night sweats); rapidly enlarging lymph[iwmf.com] Fluorescence in situ hybridization performed on the gingival biopsy specimen demonstrated the same del(20q) cytogenetic abnormality present in the bone marrow, confirming[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org] The bone marrow trephine biopsy typically shows abnormal fibrosis of the marrow cavity.[leukaemia.org.au] The hematologist may then test you further by doing a bone marrow biopsy. This consists of removing a small amount of bone marrow and examining it for abnormalities.[uihc.org]

  • Acute Myelocytic Leukemia

    Macrocytic anemia will be present unless there is an associated iron deficiency. Peripheral blood smear shows megaloblastic changes. Serum vitamin B12 levels are low.[online.epocrates.com] sweats easy bruising or petechiae (tiny red spots on the skin caused by easy bleeding) bone and joint pain belly pain (caused by the build-up of cells in organs like the[kidshealth.org] A bone marrow biopsy or a bone marrow aspiration may be done if the results of the blood tests are abnormal.[medicinenet.com]

  • Myeloproliferative Disease

    , such as macrocytic red blood cells.[doi.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] A pathologist views the bone marrow, blood, and bone under a microscope to look for abnormal cells. Bone marrow aspiration and biopsy.[rarecancers.org.au]

  • Chronic Myeloid Leukemia

    anemia, normal to increased platelet count, and increased numbers of megakaryocytes, many of which have hypolobated nuclei.[doi.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] […] counts Tests of previous bone marrow studies to look for specific chromosome abnormalities Needle aspiration or biopsy (if necessary) for a new sample of bone marrow Molecular[rush.edu]

  • Chronic Myelomonocytic Leukemia

    At the age of 83 (t   0), he started complaining of general weakness and a blood test showed profound macrocytic anemia, with no other cytopenia (Hb   7.2 g/dL; MCV   104[ojrd.biomedcentral.com] He had no symptoms of night sweats, fever, or weight loss. Review of his medical records showed a progressively increasing leukocytosis with a peak of 58 109/L.[ncbi.nlm.nih.gov] marrow studies to look for specific chromosome abnormalities Needle aspiration or biopsy (if necessary) for a new bone marrow sample Molecular test to look for certain markers[rush.edu]

  • Essential Thrombocythemia

    , may have basophils, platelets Anemia, leukocytosis, or nl platelets platelets, often abnormal Dimorphic RBC, platelets Macrocytic anemia, or nl platelets Marrow Myeloids[surgpathcriteria.stanford.edu] In one large internet-based survey of 304 patients with ET, 72% reported fatigue, and 40% or more reported itching, night sweats and bone pain.[healio.com] Bone marrow aspiration The physician uses a needle to remove a small amount of liquid bone marrow then examines it under a microscope for abnormal cells.[cancer.columbia.edu]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Case report A 71-year-old female was referred the Clinic of Hematology, in November 2007 for evaluation of the macrocytic anemia of one year duration that failed to respond[omicsonline.org] Weight loss, fever, night sweats, and reduced exercise tolerance are common complaints.[symptoma.com] sweats or splenomegaly.[orpha.net]

  • Vitamin B12 Deficiency

    Macrocytic anemias are generally classified into megaloblastic or nonmegaloblastic anemia.[doi.org] Three cases are discussed here in which drenching night sweats were thought to be caused by vitamin B12 deficiency.[ncbi.nlm.nih.gov] Biopsy of bone marrow: This is done to rule out any possibility of development of anemia, and other abnormalities concerning the red cells.[symptoma.com]

  • Polycythemia Vera

    , may have basophils, platelets Anemia, leukocytosis, or nl platelets platelets, often abnormal Dimorphic RBC, platelets Macrocytic anemia, or nl platelets Marrow Myeloids[surgpathcriteria.stanford.edu] sweats; he also reported that his spleen volume had increased rapidly in the past few months.[ncbi.nlm.nih.gov] A pathologist views the bone marrow, blood, and bone under a microscope to look for abnormal cells. Enlarge Bone marrow aspiration and biopsy.[cancer.gov]

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