Bone Marrow Gaucher Cells Causes & Reasons

Neu Starten

Ad Html Headline Ad Text Headline

Ad Label Ad Html Description Ad Text Description

Determine your risk of now. Restart test

Caution! In case of an emergency:

Seek emergency care

Hi, I'm Symptoma.

Bone Marrow Gaucher Cells Symptom Checker: Possible causes include Gaucher Disease. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

For full functionality of this site it is necessary to enable JavaScript.

How to enable JavaScript?

Possible Causes

Gaucher Disease

[…] the liver, the spleen and the bone marrow (Gaucher cells). [orpha.net]

[…] the liver, of the spleen and the bone marrow (Gaucher cells). [orpha.net]

The deficiency in glucocerebrosidase leads to the accumulation of glucosylceramidase (or beta-glucocerebrosidase) deposits in the cells of the reticuloendothelial system of [orpha.net]

Show info

Gaucher Disease Type 2

The liver, spleen, and bone marrow, except that in the temporal bone, in case 2 were normal. [ncbi.nlm.nih.gov]

[…] are most severely affected reduced T1 and T2 signal from involved bone marrow (due to infiltration of Gaucher cells ) bone marrow burden (BMB) score may be obtained from [radiopaedia.org]

The distended phagocytic cells, known as Gaucher cells, are found in the spleen, liver, bone marrow, lymph nodes, tonsils, thymus, and Peyer patches. [humpath.com]

Show info

Perinatal Lethal Gaucher Disease

[…] of the liver, spleen and bone marrow (Gaucher cells). [rarediseases.info.nih.gov]

(see Bone Marrow Biopsy, [[Bone Marrow Biopsy]]) Gaucher Cell: foamy cytoplasm Occasional Fibrosis Clinical Anemia (see Anemia, [[Anemia]]) Leukopenia (see Leukopenia, [[ [mdnxs.com]

Additionally, detection of Gaucher cells in the bone marrow or genetic analysis of GBA is frequently used as an adjunct to diagnosis.Gaucher disease has been classified into [deepdyve.com]

Show info

Anemia

[…] dyserythropoiesis Acquired: myelodysplasia Bone marrow infiltration Leukemia, lymphoma, multiple myeloma Solid tumors Myelofibrosis Thesaurismosis (Gaucher disease) Inflammatory [dx.doi.org]

Pancytopenia may be caused by intrinsic [bone marrow aplasia, leukemia, myelodysplastic syndrome (MDS) or myelofibrosis] or extrinsic (metastasis, Gaucher disease and other [dx.doi.org]

The impairment of pluripotent stem cells usually produces pancytopenia (anemia, leukopenia and thrombocytopenia). [dx.doi.org]

Show info

Neurotic Disorder

There were 21 were typical Gaucher cells having cytoplasm with crumpled/crinkled tissue paper appearance and 27 were diagnosed as non-Gaucher storage disorder. [hindawi.com]

Case Presentation In retrospective analysis of children undergoing bone marrow evaluation for suspected storage disorder (Nov 1998-October 2008), we found oldest child of [hindawi.com]

Show info

Monoclonal Gammapathy

Bone marrow infiltration by Gaucher's cells and spleen infiltration by Gaucher cells and plasma cells was observed on cytohistologic examination. [ncbi.nlm.nih.gov]

Abstract A case of chronic non-neuronopathic Gaucher's disease is presented. The diagnosis was based on the finging of typical Gaucher cells in the bone marrow spleen. [ncbi.nlm.nih.gov]

Abstract We report a case of adult-type Gaucher's disease associated with monoclonal gammapathy of undetermined significance. [ncbi.nlm.nih.gov]

Show info

Acute Infantile Liver Failure-Multisystemic Involvement Syndrome

[…] hepatomegaly : less marked than the degree of splenomegaly T2 : hyperintense stellate areas representing inflammation and fibrosis 3 areas of hepatic ischemia skeletal system long bones [radiopaedia.org]

Show info

Ichthyosis Vulgaris

marrow transplantation, or the intake of certain medications that interfere with sterol synthesis in epidermal cells (eg, nicotinic acid). [emedicine.medscape.com]

Newborns with type 2 Gaucher disease (glucosyl cerebroside lipidosis) may present with ichthyotic skin at birth prior to neurologic manifestations, which could be mistaken [emedicine.medscape.com]

[…] associated with internal neoplasia (eg, Hodgkin lymphoma, leukemia), systemic illness (eg, sarcoidosis, HIV infection, hypothyroidism, chronic hepatitis, malabsorption), bone [emedicine.medscape.com]

Show info

Cor Pulmonale

A bone marrow aspiration study revealed the presence of few large cells with abundant foamy cytoplasm and small round nucleus (Gaucher cells). [ijem.in]

[…] hepatosplenomegaly, cardiomegaly with murmurs suggestive of tricuspid regurgitation and presence of crepitation in chest, we have thought the possibility of storage disorder - mainly Gaucher [ijem.in]

Show info

Sea-blue histiocytosis

The distended phagocytic cells, known as Gaucher cells, are found in the spleen, liver, bone marrow, lymph nodes, tonsils, thymus, and Peyer patches. [medicalgeek.com]

Sea-blue histiocytes and Gaucher cells in bone marrow of patients with chronic myeloid leukaemia. J Clin Pathol. 1988; 41: 960-962. [meducator3.net]

Diagnosis Diagnosis was classically based on identification of Gaucher cells in a bone marrow aspirate. [path.upmc.edu]

Show info

Epilepsy

Bone marrow evaluation revealed Gaucher cells, confirming the diagnosis. BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. [ncbi.nlm.nih.gov]

Show info

Gaucher Disease Type 1

[…] the liver, of the spleen and the bone marrow (Gaucher cells). [orpha.net]

The median number of Gaucher cells identified during cytological assessment of bone marrow smears was 4 (range, 1-18), and the median percentage of Gaucher cells was 0.4% [ncbi.nlm.nih.gov]

The deficiency in glucocerebrosidase leads to the accumulation of glucosylceramidase (or beta-glucocerebrosidase) deposits in the cells of the reticuloendothelial system of [orpha.net]

Show info

Neuralgia

There were 21 were typical Gaucher cells having cytoplasm with crumpled/crinkled tissue paper appearance and 27 were diagnosed as non-Gaucher storage disorder. [hindawi.com]

Case Presentation In retrospective analysis of children undergoing bone marrow evaluation for suspected storage disorder (Nov 1998-October 2008), we found oldest child of [hindawi.com]

Show info

Progressive Myoclonic Epilepsy Type 3

Bone marrow examination shows lipid-engorged macrophages with eccentric nuclei (Gaucher cells). [clinicalgate.com]

However, these are nonspecific, and bone marrow examination is not a reliable diagnostic test. The GBA gene is the only gene known to be associated with GD. [clinicalgate.com]

Show info

Bone Necrosis

[…] sickle cell disease, leukemia, Gaucher's disease, thalassemia), and underwater diver's disease (from bone effects of Caisson disease, also known as dysbarism or "the bends [emedicinehealth.com]

[…] where large polyhedral Gaucher cells accumulate Their pressure on bone sinusoids may bone necrosis Tendency for lesions to become infected septicaemia Associated with: Anaemia [flinders.edu.au]

[…] disease sickle cell disease caisson disease ("the bends") Pathogenesis impaired blood supply leads to infarction of the associated bone and bone marrow vascular insufficiency [medbullets.com]

Show info

Primary Mediastinal Large B-Cell Lymphoma

Myelophthisic Anemias Metastatic Lesions in Bone Marrow Biopsies Gaucher Disease Storage Disorders: Niemann-Pick Disease (NPD) G. [euro-libris.ro]

Red Cell Aplasias Red Cell Aplasia Parvovirus Infection III. [euro-libris.ro]

Show info

Leukoerythroblastic Anemia

Gaucher cells clog or infiltrate the bone marrow, spleen, and liver. This disorder is inherited. [emedicine.medscape.com]

This bone marrow film at 400X magnification demonstrates carcinoma metastasis. Bone marrow cells are completely replaced by large carcinoma cells with clear nucleoli. [emedicine.medscape.com]

[…] disease, infiltration by cells with "onion-peel" cytoplasm, called Gaucher cells, is caused by a lipid storage disorder (ie, glucosylceramide lipidosis). [emedicine.medscape.com]

Show info

Avascular Necrosis

[…] disease, and systemic lupus erythematosus. - biblioghraphy : Avascular necrosis of bone: a common serious complication of allogeneic bone marrow transplantation. [pitt.edu]

Other risk factors for developing avascular necrosis include cigarette smoking, pregnancy, radiation and chemotherapy treatments, bone marrow and blood diseases (including [emedicinehealth.com]

Show info

Osteomyelitis of the Frontal Bone

Microscopic Features: [15] Lamellar bone. Fibrotic marrow space with: Collagen. Low cellularity. Spindle cells without significant atypia. [librepathology.org]

Microscopic Macrophages in the marrow space with a "crumpled tissue paper" appearance. Langerhans cell histiocytosis of bone AKA eosinophilic granuloma of bone. [librepathology.org]

DDx: Fibrous dysplasia - has woven bone. Low grade fibrosarcoma. Gaucher disease General May present as a fracture. [librepathology.org]

Show info

Gaucher Disease Type 3

Progressive infiltration of Gaucher cells in the bone marrow may lead to thinning of the cortex, pathologic fractures, bone pain, bony infarcts, and osteopenia. [emedicine.medscape.com]

Gaucher cells are present throughout the body, but the largest numbers are found in the spleen, liver, bone marrow, and lymph nodes causing enlargement and dysfunction of [cochranelibrary.com]

marrow, liver, spleen, lungs, and other organs contributes to pancytopenia, massive hepatosplenomegaly, and, at times, diffuse infiltrative pulmonary disease. [emedicine.medscape.com]

Show info

Congenital Dyserythropoietic Anemia

These cases differ from those previously described in that Gaucher-like histiocytes were present in bone marrow aspirates from all affected children. [annals.org]

Many pseudo-Gaucher cells were also seen. Iron stores were increased although ring sideroblasts were absent. [ncbi.nlm.nih.gov]

One of the patients demonstrated Gaucher cells in the marrow as a presumed consequence of the increased rate of red blood cell destruction. [pediatrics.aappublications.org]

Show info

Interstitial Pulmonary Fibrosis of the Newborn

bone marrow, lymph nodes and the central nervous system. [err.ersjournals.com]

The hallmark of Gaucher disease is the presence of lipid-laden macrophages (Gaucher cells) in a variety of tissues, the largest number of them being found in the spleen, liver [err.ersjournals.com]

A significant phenotypic variability resulting from Gaucher disease genetic heterogeneity has been reported [ 37, 38 ]. [err.ersjournals.com]

Show info

Myelophthisis

Gaucher cells clog or infiltrate the bone marrow, spleen, and liver. This disorder is inherited. [emedicine.com]

This bone marrow film at 400X magnification demonstrates carcinoma metastasis. Bone marrow cells are completely replaced by large carcinoma cells with clear nucleoli. [emedicine.com]

[…] disease, infiltration by cells with "onion-peel" cytoplasm, called Gaucher cells, is caused by a lipid storage disorder (ie, glucosylceramide lipidosis). [emedicine.com]

Show info

Malignant Neoplasm of the Stomach

Bone marrow aspirations 10 months after the start of the treatment with velaglucerase α showed reduction of Gaucher cells in bone marrow to 2% from 4% of total cellularity [ncbi.nlm.nih.gov]

Show info

Fabry Disease

In this lysosomal storage disorder (LSD), clinical features are reflective of the distribution of Gaucher cells in the liver, spleen, bone marrow, skeleton, and lungs. [fiercebiotech.com]

Progressive infiltration of Gaucher cells in the bone marrow may lead to thinning of the cortex, pathologic fractures, bone pain, bony infarcts, and osteopenia. [emedicine.medscape.com]

Characterisation of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. [ncbi.nlm.nih.gov]

Show info

Necrosis of the Jaw

Other risk factors for developing avascular necrosis include cigarette smoking, pregnancy, radiation and chemotherapy treatments, bone marrow and blood diseases (including [emedicinehealth.com]

Show info

Adult Idiopathic Neutropenia

marrow replacement (eg, due to cancer, myelofibrosis, granuloma, or Gaucher cells) Cytotoxic chemotherapy or radiation therapy Drug-induced neutropenia Folate deficiency, [merckmanuals.com]

[…] storage disease type IB, WHIM* syndrome, Shwachman-Diamond syndrome) Secondary neutropenias Alcoholism Autoimmune neutropenia, including chronic secondary neutropenia in AIDS Bone [merckmanuals.com]

Show info

Spleen Disease

Gaucher patients may experience severe bone pain, called “bone crisis,” because Gaucher cells in the bone marrow may prevent blood from circulating properly. [cerezyme.com]

Gaucher cells accumulate primarily in the spleen, liver and bone marrow, causing organ inflammation and dysfunction. [gaucherdisease.org]

Gaucher cells accumulate primarily in the spleen, liver and bone marrow, causing organ inflammation and dysfunction. What are the Symptoms of Gaucher Disease? [gaucherdisease.org]

Show info

Myelodysplasia

Judit Várkonyi, Miklós Molnár, Margit Kovács and Zoltán Prohászka, Iron Overload in Gaucher Cells and Bone Marrow that Is Not Associated with Hemochromatosis Gene Mutations [doi.org]

C282Y and H63D in a Patient Having Coexistent Gaucher and Parkinson’s Disease, Hungarian Medical Journal, 10.1556/HMJ.1.2007.3.10, 1, 3, (371-374), (2007). [doi.org]

Show info

Agranulocytosis

marrow replacement (eg, due to cancer, myelofibrosis, granuloma, or Gaucher cells) Cytotoxic chemotherapy or radiation therapy Drug-induced neutropenia Folate deficiency, [merckmanuals.com]

Show info

⚕ Symptoma®️ is a digital health assistant but no replacement for the opinion and judgement of medical professionals. By using this website you fully understand and accept that it shall not be used as a diagnostic system for decision-making. It absolutely must not be used to obtain, replace or overrule a clinical diagnosis by a healthcare professional. It is always for the medical professional to make the final diagnosis. The medical information provided on this website is of a general nature and can not substitute for the advice of a medical professional (for example, a qualified doctor or physician)! Information from the internet could and should NOT be solely used to offer or render a medical opinion or otherwise engage in the practice of medicine.