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12 Possible Causes for Bone Marrow with Decreased Iron Stores, Plummer-Vinson Syndrome

  • Plummer-Vinson Syndrome

    The authors report the case of a 6 year old with Plummer-Vinson syndrome.[ncbi.nlm.nih.gov] Plummer-Vinson syndrome can be treated effectively with iron supplementation and mechanical dilation.[ncbi.nlm.nih.gov] OBJECTIVE: Very few cases of Plummer-Vinson syndrome affecting males have been reported.[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    The most used name is Plummer-Vinson syndrome, named after Henry Stanley Plummer (1874–1936) and Porter Paisley Vinson (1890–1959) who were physicians on the staff of the[dx.doi.org] Iron depletion: The first thing that occurs is decreased bone marrow iron (seen as hemosiderin on Prussian-blue stained bone marrow smears) as iron stores are used to maintain[eclinpath.com] iron stores in the bone marrow.[doi.org]

  • Iron Deficiency

    Symptoms of iron deficiency include: fatigue dizziness/lightheadedness pallor hair loss twitches irritability weakness pica brittle or grooved nails hair thinning PlummerVinson[en.wikipedia.org] In the first stage, iron requirement exceeds intake, causing progressive depletion of bone marrow iron stores.[merckmanuals.com] This is the Paterson-Brown-Kelly syndrome (or Plummer-Vinson syndrome) and there is an association with oesophageal carcinoma.[patient.info]

  • Microcytic Anemia

    Koilonychia- "spoon nails" [koi-loh-nik-ee-uh] What does Plummer-Vinson Syndrome look like in severe iron deficiency anemia?[quizlet.com] In the first stage, iron requirement exceeds intake, causing progressive depletion of bone marrow iron stores.[merckmanuals.com] Erythrocyte Protoporhyrin Because less haem to bind to protoporhyrin to make Hb Bone marrow biopsy Little or no iron on marrow when deficient Rx Underlying cause Ferrous sulfate Plummer-Vinson[alancam.com]

  • Posthemorrhagic Anaemia of the Newborn

    Plummer-Vinson syndrome Sideropenic dysphagia 280.9 Iron deficiency anemia, unspecified Anemia: achlorhydric chlorotic idiopathic hypochromic iron [Fe] deficiency NOS 281[theodora.com] […] most common type of normocytic anemia Anemia of Chronic Disease/Inflammation Pathophysiology - Increased accumulation of iron stores in macrophages - Decreased delivery of[quizlet.com] Plummer-Vinson syndrome D50.8 Other iron deficiency anemias Iron deficiency anemia due to inadequate dietary iron intake D50.9 Iron deficiency anemia, unspecified D51 Vitamin[en.wikisource.org]

  • Constitutional Megaloblastic Anemia due to Folate Metabolism Disorder

    […] of neuroepithelial tissue Pineoblastoma Pineocytoma Plaque-form urticaria pigmentosa Plasma cell tumor Plasmacytoma Pleomorphic liposarcoma Pleomorphic rhabdomyosarcoma Plummer-Vinson[se-atlas.de] […] from the stores, decrease the responsiveness of the bone marrow to erythropoetin.[freezingblue.com] […] brittle nails, cheliosis, smooth tongue, formation of esophageal webs (Plummer-Vinson syndrome) Laboratory findings in iron deficiency anemia?[studystack.com]

  • Gaisbock's Syndrome

    Plummer vinson syndrome/Paterson brown kelly syndrome -Combination of symptomatic hypo pharyngeal webs and iron deficiency anemia in mddle aged female.Radiological finding-web[masterofmedicine.com] stores are decreased, often absent Post PV / spent phase: (Figures D - G) Leukoerythroblastosis Overt bone marrow reticulin and collagen fibrosis Osteosclerosis usually prominent[pathologyoutlines.com] marrow Panhyperplasia Erythroid hyperplasia N Iron stores N N Chromosome studies Abnormal (50%) N N LABORATORY DIFFERENTIAL OF POLYCYTHEMIA # Hb, # Hct, # RBC ABSOLUTE Red[sites.google.com]

  • Red Blood Cell Disorder

    . • First described by Plummer and VinsonPlummer-Vinson syndrome is potentially serious because pharyngeal and intraoral carcinoma are more common in these patients. •[slideshare.net] Its synthesized by the bone marrow macrophages and hepatocytes. Serum iron levels correlate with ferritin stores in the macrophages.[slideplayer.com] Decreased serum ferritin in diagnostic of iron deficiency anemia. Hemosiderin is a breakdown product of ferritin. 11 Iron studies.[slideplayer.com]

  • Anemia of Chronic Disease

    Rare symptoms & signs: -Glossitis or angular cheilitis -Dysphagia due to esophageal web (Plummer-Vinson syndrome) -Koilonychia; "Spoon" fingernails -Pica -soreness of mouth[quizlet.com] Hepcidin is a key that locks up iron in the bone marrow and prevents it’s release to transferrin. That’s why, ferritin is increased. (Stores are there, but unavailable!)[medicowesome.com] Bone marrow iron stores are usually increased. Ferritin (an acute phase reactant) may be elevated in inflammation.[med-ed.virginia.edu]

  • Inadequate Dietary Intake of Iron

    Although it is a rare condition, Plummer-Vinson syndrome (IDA associated with difficulty swallowing, enlarged spleen, and spooning of the nails) may occur in severe cases[medical-dictionary.thefreedictionary.com] marrow decrease.[ods.od.nih.gov] Iron depletion and deficiency progresses through several stages [ 8 ]: Mild deficiency or storage iron depletion: Serum ferritin concentrations and levels of iron in bone[ods.od.nih.gov]

Further symptoms