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35 Possible Causes for Bone Marrow with Erythrophagocytosis

  • Malignant Histiocytosis

    Two young men developed bone marrow infiltration with histiocytes showing erythrophagocytosis shortly after subtotal excision of a malignant teratoma of the anterior mediastinum[] Large blasts with low nuclear/cytoplasmic ratios, occasional azurophilic granules, and immature nuclei with nucleoli were seen in peripheral blood and bone marrow smears.[] Bone marrow infiltration by the neoplastic cells and numerous reactive cells with erythrophagocytosis appears to be an important factor of profound cytopenia in patients of[]

  • Pyruvate Kinase Deficiency

    Mutations in the PKLR gene responsible for pyruvate kinase (PK)-deficient anaemia are mainly located in the coding regions: 11 are in the splicing sites and, recently, three mutations have been described in the promoter region. We now report a novel point mutation A-- G on nucleotide 72, upstream from the initiation[…][]

  • Microangiopathic Hemolytic Anemia

    There are 3 species of hump-nosed pit vipers in Sri Lanka: Hypnale hypnale, Hypnale zara, and Hypnale nepa. The latter 2 are endemic to the country. Microangiopathic hemolytic anemia (MAHA) is a known complication of hump-nosed pit viper bites. It was previously documented as a complication of general viper bites[…][]

  • Typhus

    Queensland tick typhus (QTT), caused by Rickettsia australis, is usually a relatively mild illness but can occasionally be severe. We describe three cases of probable QTT with unusual clinical features, namely splenic infarction, fulminant myopericarditis and severe leukocytoclastic vasculitis. QTT may present with[…][]

  • Autoimmune Hemolytic Anemia

    Warm antibody autoimmune hemolytic anemia (AIHA) results from targeted antibodies towards the red blood cells (RBCs) and can be either idiopathic or secondary to certain diseases, such as autoimmune disorders or malignancy, drugs, or infection. Patients with DiGeorge syndrome are particularly vulnerable to[…][]

  • Erythema Infectiosum

    Erythema infectiosum (EI) is a common childhood illness, caused by human parvovirus B19. It occurs sporadically or in epidemics and is characterized by mild constitutional symptoms and a blotchy or maculopapular lacy rash on the cheeks (slapped-cheek) spreading primarily to the extremities and trunk. The aim of our[…][]

  • Rare Form of Salmonellosis

    This paper describes a rare delusional disorder, the Fregoli syndrome, in a 17 year old girl who suffered from typhoid psychosis as seen at the Psychiatric Unit of the Jos University Teaching Hospital, Jos.[]

  • Gaucher Disease

    Although the majority of stored glucocerebroside in GC is of erythrocyte origin, apparent erythrophagocytosis by GC in bone marrow is an unusual finding.[]

  • Chronic Eosinophilic Leukemia

    Prominent erythrophagocytosis by eosinophils was visualized in the blood and in the bone marrow.[] Numerous Charcot-Leyden crystals were also seen in the bone marrow amid increased numbers of eosinophils and the presence of dysplastic granulopoiesis.[] More significantly, this represents the first case report to describe erythrophagocytosis by eosinophils.[]

  • Monoclonal Gammopathy of Undetermined Significance

    Bone marrow examination in a 78-year-old woman showed a plasmacytosis with prominent erythrophagocytosis, secretory activity and numerous Russell bodies.[]

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