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46 Possible Causes for Bone Marrow with Foam Cells

  • Niemann-Pick Disease Type B

    Bone marrow biopsy showed plenty of foam cells and sphingomyelinase level was low, thus conforming our diagnosis.[ncbi.nlm.nih.gov] Although pseudo-Gaucher cells and sea blue histiocytes can be found in bone marrow that is rapidly turning over, the combination of both numerous foam cells and sea blue histiocytes[imagebank.hematology.org] cells in the bone marrow aspirate.[ncbi.nlm.nih.gov]

  • Niemann-Pick Disease

    Bone marrow biopsy showed plenty of foam cells and sphingomyelinase level was low, thus conforming our diagnosis.[ncbi.nlm.nih.gov] Foam cells were present in the bone marrow aspirate too, that contained also sea-blue histiocytes.[ncbi.nlm.nih.gov] marrow will show abnormal foam cells) Type C: biochemical test - skin biopsy taken and the fibroblasts are tested for their ability to handle cholesterol (esterification[en.wikibooks.org]

  • Wolman Disease

    […] acid cholesteryl ester hydrolase deficiency disseminated organ foam cell infiltration bone marrow foam cells vacuolated blood lymphocytes liver, adrenal, spleen , lymph nodes[humpath.com] cells in the bone marrow and other tissues.[whonamedit.com] Differential diagnosis In Wolman disease foam cells are found in bone marrow and vacuolated lymphocytes in peripheral blood, as in Niemann-Pick disease type A and B (acid[bredagenetics.com]

  • Cholesterol Ester Storage Disease

    cells in bone marrow and other tissues, and vacuolated lymphocytes in peripheral blood; autosomal recessive inheritance, caused by mutation in the lysosomal acid lipase gene[medical-dictionary.thefreedictionary.com] Peripheral blood lymphocytes are vacuolated and foam cells are present in the bone marrow. Approximately 50% of infants have adrenal calcifications.[mayomedicallaboratories.com] Differential diagnosis In Wolman disease foam cells are found in bone marrow and vacuolated lymphocytes in peripheral blood, as in Niemann-Pick disease type A and B (acid[bredagenetics.com]

  • Niemann-Pick Disease Type D

    […] and histiocytes in several organs as lung, liver, spleen, kidney. microvacuolated hepatocytes (hepatic microsteatosis) large vacuolated foam cells (’NP cells’) on bone marrow[humpath.com] Bone marrow examination was done which showed characteristic lipid-laden foam cell termed ie Niemann-Pick cells.[jmscr.igmpublication.org] bone marrow.[medindia.net]

  • Tangier Disease

    marrow foam cells), was misdiagnosed as Niemann-Pick C (NPC) and treated with miglustat (300 mg/day), normalizing neurological symptoms and improving skin lesions and legs[ncbi.nlm.nih.gov] Subsequently, the diagnosis of homozygous Tangier disease was also established by biopsy of the patient’s bone marrow, showing the presence of foam cells (Figure 1 ).[circ.ahajournals.org] Bone marrow biopsy was also suggestive of lipid storage disease.[ncbi.nlm.nih.gov]

  • Galactosialidosis

    All patients have clinical manifestations typical of a lysosomal disorder, such as coarse facies, cherry red spots, vertebral changes, foam cells in the bone marrow, and vacuolated[uniprot.org] All patients have clinical manifestations typical of a lysosomal storage disease, including coarse facies, cherry-red spots, vertebral changes, foam cells in the bone marrow[ommbid.mhmedical.com] cells in the bone marrow -vacuolated lymphocytes *due to the range of phenotypic ariation of this disorder it has been divided into 3 subgroups.[mbcproject2013.blogspot.com]

  • Gangliosidosis GM1

    Vacuolated lymphocytes in peripheral blood and foam cells in bone marrow; Hurler-like radiographic bone anomalies in infantile form; measurement of enzymatic activity in peripheral[accessanesthesiology.mhmedical.com] Gaucher-like foam cells have been reported on bone marrow examination.[orpha.net] […] resulting in abnormal accumulation of G M1 ganglioside in the lysosomes of neurons and of oligosaccharides in hepatic, splenic, and other histiocytes and in renal glomerular cells[accessanesthesiology.mhmedical.com]

  • Propionic Acidemia

    marrow vacuolization , foam cells or granules.[vdocuments.site] […] vacuolization, foam cells or granules.[vdocuments.mx] . • DNA studies • Neuro-radiology • • Blood glucose, ammonia, bicarbonate and pH Peripheral Blood smear – WBC or bone marrow vacuolization , foam cells or granules.[nanopdf.com]

  • Generalized Clonic or Tonic-Clonic Seizures

    foam cells Head tremor Foam cells Aplasia/Hypoplasia of the abdominal wall musculature Spastic dysarthria Supranuclear gaze palsy Vertical supranuclear gaze palsy Visceromegaly[mendelian.co] Astrocytosis Anemia Apathy Diplopia Childhood onset Urinary retention Hypersomnia Snoring Hallucinations Stridor Apnea Mitral valve prolapse Abnormality of the nervous system Bone-marrow[mendelian.co]

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