Create issue ticket

14 Possible Causes for Bone Marrow with Giant Metamyelocytes, Pernicious Anemia not due to Intrinsic Factor Deficiency

  • Vitamin B12 Deficiency

    In pernicious anemia, the intrinsic factor necessary for vitamin B12 absorption is lacking, often due to an autoimmune factor.[livestrong.com] In B12 and folate deficiency, megaloblasts and giant metamyelocytes (early granulocyte precursors) are seen. [ 9 ] Gastric secretions Total gastric secretions are reduced[patient.info] […] term pernicious anemia is sometimes used colloquially to refer to any anemia caused by vitamin B12 deficiency.[uofmhealth.org]

  • Pernicious Anemia

    Technically, the term "pernicious anemia" refers to vitamin B12 deficiency due to a lack of intrinsic factor.[web.archive.org] Bone marrow biopsy: The abnormalities seen in bone marrow include large cell size, giant metamyelocytes and marked erythroid hyperplasia.[symptoma.com] In B12 and folate deficiency, megaloblasts and giant metamyelocytes (early granulocyte precursors) are seen. [ 9 ] Gastric secretions Total gastric secretions are reduced[patient.info]

  • Megaloblastic Anemia

    Megaloblastic anemia that arises due to lack of intrinsic factor is called pernicious anemia.[medindia.net] White blood cells show giant metamyelocytes in the bone marrow are a characteristic feature. Megakaryocytes are also abnormal.[labpedia.net] Megaloblastic anemia that arises due to lack of intrinsic factor is called pernicious anemia .[medindia.net]

  • Megaloblastic Anaemia in Pregnancy

    It results in a malignant condition named pernicious anemia due to major vitamin B12 deficiency as the intrinsic factor is responsible for absorbing the vitamin in the intestine[pregmed.org] Megaloblastic anemia that arises due to lack of intrinsic factor is called pernicious anemia .[medindia.net] Pernicious anemia: Sometimes, abnormal immune reaction can lead to loss of certain stomach cells responsible for producing the intrinsic factor.[pregmed.org]

  • Congenital Vitamin B12 Deficiency

    anemia Biermer anemia Pernicious (congenital) anemia Congenital intrinsic factor deficiency D51.1 Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption[icd10coded.com] The additional finding of hypersegmented polymorphonuclear neutrophils should point to the likelihood of megaloblastic anemia, and a bone marrow aspirate could clinch the[cancertherapyadvisor.com] Convert to ICD-10-CM : 281.0 converts approximately to: 2015/16 ICD-10-CM D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency 281.0 Excludes Applies To[icd9data.com]

  • Congenital Intrinsic Factor Deficiency

    anemia - Gastric intrinsic factor deficiency - Hereditary juvenile meganoblastic anemia due to intrinsic factor deficiency - IFD - Intrinsic factor deficiency Classification[csbg.cnb.csic.es] Bone Marrow  Hypercellular marrow  Megaloblastic erythroid hyperplasia  Giant metamyelocytes Due to slowing of DNA synthesis and delayed nuclear maturation Methionine deficiency[slideshare.net] In B12 and folate deficiency, megaloblasts and giant metamyelocytes (early granulocyte precursors) are seen. [ 9 ] Gastric secretions Total gastric secretions are reduced[patient.info]

  • Folate-Deficiency Anemia

    Megaloblastic anemia due to vitamin B12 deficiency caused by a lack of intrinsic factor is specifically referred to as pernicious anemia.[med-ed.virginia.edu] Megaloblastic anemia is most often due to a B12 or folate deficiency, but the cause of the deficiency must be determined for proper treatment.[med-ed.virginia.edu]

  • Autoimmune Gastritis

    Besides these conditions, iron deficiency, pernicious anemia, and autoimmune gastritis were also diagnosed.[ncbi.nlm.nih.gov] marrow Hypercellular bone marrow Increased erythroid precursors Open, immature nuclear chromatin Dyssynchrony between maturation of cytoplasm and nuclei Giant bands, metamyelocytes[wjgnet.com] anemia , a megaloblastic anemia arising from vitamin B 12 malabsorption as a consequence of intrinsic factor deficiency, [7,8] or the iron deficiency anemia due to iron malabsorption[journals.lww.com]

  • Subacute Combined Degeneration of Spinal Cord

    anemia 2016 2017 2018 2019 Billable/Specific Code Applicable To Vegan anemia D51.3 ) pernicious ( ICD-10-CM Diagnosis Code D51.0 Vitamin B12 deficiency anemia due to intrinsic[icd10data.com] The bone marrow is hypercellular with megaloblastic erythroid hyperplasia and giant metamyelocytes.[scielo.br] , [3] and copper deficiency. [4] It is usually associated with pernicious anemia.[ipfs.io]

  • Congenital Malabsorption of Folic Acid

    […] thyroid disease -Congenital deficiency of intrinsic factor or congenital selective Vit B12 malabsorption due to defects of the receptor sites in the distal ileum Why can B12[quizlet.com] The additional finding of hypersegmented polymorphonuclear neutrophils should point to the likelihood of megaloblastic anemia, and a bone marrow aspirate could clinch the[thecardiologyadvisor.com] […] to lymphoma or TB Intrinsic factor deficiency (as in pernicious anemia) Lymphangiectasia Symptoms and Signs The effects of unabsorbed substances, especially in global malabsorption[msdmanuals.com]

Further symptoms