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16 Possible Causes for Bone Marrow with Increased Iron Stores, Congenital Nonspherocytic Hemolytic Anemia, Dyspnea

  • Autoimmune Hemolytic Anemia

    The patient suddenly developed hematuria and dyspnea on exertion while receiving adalimumab treatment.[] In 2013, he complained of dyspnea. Chest computed tomography showed postoperative recurrence of invasive thymoma. Several chemotherapies were administered.[] A 12-year-old male child presented to the emergency room with three days history of cola-colored urine, mild icterus, dyspnea, palpitation and fatigue.[]

  • Pyruvate Kinase Deficiency

    In this later group of "congenital nonspherocytic hemolytic anemias" splenectomy has often been performed but usually does not produce a clinical cure.[] SIGNS AND SYMPTOMS Fatigue Lethargy Jaundice  Pallor (Paleness of skin)  Dyspnea (Shortness of breath) Tachycardia (Rapid heart rate ). (Grace et al., 2015). 7.[] congenital nonspherocytic hemolytic anemia that has material basis in homozygous or compound heterozygous mutation in the PKLR gene on chromosome 1q22 pyruvate kinase deficiency[]

  • Hereditary Spherocytosis

    Anemia – paleness (pallor), fatigue, dyspnea (shortness of breath). Jaundice - yellow discoloration of the skin and white part of eyeball.[] The main clinical features observed during the first months of life were pallor, dyspnea (mild difficulties in breathing while feeding), or both, related to anemia in 31 of[]

  • Congenital Hemolytic Anemia

    This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding[] Patients can develop uncompensated anemia with marked weakness and dyspnea, pallor, tachycardia and incipient heart failure.[] Within minutes, the patient may develop fever, chills, dyspnea, hypotension, and shock.[]

  • Acquired Toxic Hemolytic Anemia

    Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[] The disease is characterized by symptoms due to the anemia including fatigue, exertional dyspnea, and, more rarely, jaundice and dark urine in case of severe hemolysis.[] Presenting symptoms and signs of hemolytic anemia include those common to anemia in general: weakness or fatigue; dizziness; shortness of breath with dyspnea on exertion;[]

  • Acquired Hemolytic Anemia

    Assuming the bone marrow is normal and there are sufficient erythropoeitin and iron stores, acute anemia (ie. hemolysis or blood loss) should increase the retic % to 4-6%[] Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[] Anemia may lead to cardiovascular symptoms such as dyspnea, angina and tachycardia; or nonspecific complaints of generalized malaise and dizziness.[]

  • Red Blood Cell Disorder

    Ferritin: soluble iron binding storage protein also helps to keep iron in its non toxic form. Its synthesized by the bone marrow macrophages and hepatocytes.[] Summary Epidemiology PK deficiency is the most frequent cause of congenital nonspherocytic hemolytic anemia with a prevalence estimated at 1/20,000 in the general white population[] Schick, MD A 45 year-old woman presents with fatigue, dyspnea, and menorrhagia. V-3 - Anemia and Hashimoto Thyroiditis Caroline Cromwell, MD, and Marc J.[]

  • Hexokinase Deficiency

    Ferritin, iron, and transferrin saturation are increased. Bone marrow shows hypercellularity with increased iron stores, increased sideroblasts, and ring sideroblasts.[] The findings were entirely different from those of subsequently reported cases with congenital, nonspherocytic hemolytic anemia associated only with a specific deficiency[] […] recessive inheritance ; Cholecystitis ; Cholelithiasis ; Congenital onset ; Hyperbilirubinemia ; Jaundice ; Nonspherocytic hemolytic anemia ; Normochromic anemia ; Normocytic[]

  • Hereditary Sideroblastic Anemia

    ; increase in iron store will need less transferrin, low TIBC).[] nonspherocytic hemolytic anemia * (n) 先天性貧血 P614 ** せんてんせいひんけつ PubMed, Scholar, Google, WikiPedia congenital anemia * (n*) 先天性溶血性貧血 *** せんてんせいようけつせいひんけつ シソーラス PubMed, Scholar[] Moderate to severe anemia with fatigue, dizziness, and dyspnea should prompt an evaluation for SA.[]

  • Congenital Dyserythropoietic Anemia

    Iron stores were increased although ring sideroblasts were absent.[] , type I Congenital dyserythropoietic anemia, type II Congenital dyserythropoietic anemia, type III Congenital nonspherocytic hemolytic anemia due to inborn error of metabolism[] We report the case of a 32-year-old woman who was admitted at hospital because of ortho-dyspnea, arrhythmia, and paleness.[]

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