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54 Possible Causes for Bone Marrow with Increased Iron Stores, Hematocrit Decreased, Reticulocytes Increased

  • Hereditary Spherocytosis

    Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] Reticulocytes decreased to 0%. Spherocytosis was present on the peripheral blood smear.[bmcresnotes.biomedcentral.com]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org] Laboratory data showed low hemoglobin levels and slightly increased reticulocyte counts, while direct and indirect antiglobulin tests were positive.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov] On her third day of admission, due to hemoglobin (Hb) value of 6.9 g/dL with increase in reticulocytes, the patient was transfused with one unit of compatible leukodepleted[ncbi.nlm.nih.gov]

  • Congenital Hemolytic Anemia

    After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net] Laboratory studies show evidence not only of many spherocytes but also increased numbers of reticulocytes (young red blood cells), hyperbilirubinemia (increased blood levels[medicinenet.com]

  • Hodgkin Lymphoma

    The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…][ncbi.nlm.nih.gov]

  • Pyruvate Kinase Deficiency

    Char10C mice also display a reduction in anemia phenotypes associated with the PklrG338D mutation including decreased splenomegaly, decreased circulating reticulocytes, increased[ncbi.nlm.nih.gov] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net] Hemoglobin measurement also shows a decrease to 6–12g/dL where normal ranges from 12–16.5g/dL.[themedicalbiochemistrypage.org]

  • Congenital Dyserythropoietic Anemia

    Iron stores were increased although ring sideroblasts were absent.[ncbi.nlm.nih.gov] On this treatment, hemoglobin and reticulocytes increased and transfusions became unnecessary.[ncbi.nlm.nih.gov] Following delivery the infant had serial blood counts performed over a 6-week period, which noted a steady decrease in her hematocrit to 16%.[bloodjournal.org]

  • Sideroblastic Anemia

    Diagnosis made by examination of the bone marrow 1- Marked erythoid hyperplasia; a sign of ineffective erytropoieses 2- Prussian blue iron strain stores bone marrow shows[quizlet.com] Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decreased Microcytic, hypochromic anemia Reticulocytes[5minuteconsult.com] Blood 2017 129:2710; doi: A 3-month-old boy presented with decreased appetite, fatigue, and a nosebleed.[bloodjournal.org]

  • Megaloblastic Anemia

    Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decreased Microcytic, hypochromic anemia Reticulocytes[5minuteconsult.com] Hematocrit – decreased3. RBC count – decreased/normal4. MCV - 100fl ( normal 82-98fl)5. MCH –increased6. MCHC – NORMAL7. Reticulocytopenia.8.[slideshare.net] Catabolism of hemoglobin by the reticuloendothelial cells of the marrow and liver accounts for the increased iron stores and the bilirubinemias [7].[path.upmc.edu]

  • Pernicious Anemia

    Change in the frequency of bowel movements, temporary increase of reticulocytes in the peripheral blood, and decrease of the icterus index of the blood serum were among the[bloodjournal.org] […] in serum vitamin B 12 and the decline in hematocrit.[aafp.org] Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov]

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