Bone Pain: Causes & Reasons

Possible Causes for Bone Pain

METHODS: Patients with leg pain, defined as local pain and tenderness over tibial bones for ≥ 6 weeks were consecutively selected. [ncbi.nlm.nih.gov]

Patients with vitamin D deficiency can present with nonspecific bone pain and findings on radionuclide bone scanning that may suggest metastatic malignancy. [ncbi.nlm.nih.gov]

All had generalized bone pain and tenderness, muscle weakness, stooping posture, difficulty walking, and waddling gait due to severe proximal muscle weakness for a period [ncbi.nlm.nih.gov]

Periostitis

A renal transplant recipient who was on voriconazole for invasive aspergillosis developed diffuse debilitating symmetrical bone pain. [ncbi.nlm.nih.gov]

The diagnosis of periostitis was made by the documentation of bone pain, elevation of serum alkaline phosphatase and characteristic findings on radionuclide bone imaging in [ncbi.nlm.nih.gov]

We review the previous literature regarding syphilitic bone pain and periostitis. [ncbi.nlm.nih.gov]

Stage IV Prostate Carcinoma

Chemotherapy can also be highly effective in reducing bone pain. [pcf.org]

Effective therapies are available to halt or slow cancer growth and to relieve symptoms, such as bone pain and weakness, and make your quality of life the best it can be. [healthmonitor.com]

bone loss, fracture, and joint pain. [zerocancer.org]

Osteomyelitis

Chronic osteomyelitis causes intermittent (months to many years) bone pain, tenderness, and draining sinuses. [merckmanuals.com]

Signs and symptoms vary but may include bone pain, fever, chills, excessive sweating, malaise, or an open wound. [web.archive.org]

Acute osteomyelitis is suspected in patients with localized peripheral bone pain, fever, and malaise or with localized refractory vertebral pain, particularly in patients [merckmanuals.com]

Malignant Neoplasm of the Lung

If the cancer has spread to the bones, it may cause bone pain, often in the vertebrae or ribs. [cancercenter.com]

Pain. Advanced lung cancer that spreads to the lining of a lung or to another area of the body, such as a bone, can cause pain. [mayoclinic.org]

Signs and symptoms that might appear if the cancer has spread to other places include bone pain, headache, muscle weakness and/or eyelid drooping. [my.clevelandclinic.org]

Osteoporosis

Transient osteoporosis of the hip (TOH) is characterized by bone pain, osteopenia, and bone marrow edema in the absence of trauma. [ncbi.nlm.nih.gov]

Improvement of bone density, pain, and quality of life was achieved. [ncbi.nlm.nih.gov]

Most claim their bone pain is completely gone. The best part is that bone pain usually goes away within 2-3 hours after the operation!). [parathyroid.com]

Multiple Myeloma

(who, 2001) Malignant neoplasm of plasma cells usually arising in the bone marrow and manifested by skeletal destruction, bone pain, and the presence of anomalous immunoglobulins [icd9data.com]

Bone problems. Multiple myeloma can also affect your bones, leading to bone pain, thinning bones and broken bones. Reduced kidney function. [mayoclinic.org]

Eventually, myeloma causes a wide range of problems, including: a persistent bone pain, usually in the back, ribs or hips tiredness, weakness and shortness of breath – caused [nhs.uk]

Schnitzler Syndrome

Often, the areas of hyperostosis coincide with areas of symptomatic bone pain, such as the iliac bone, tibia, femur, and vertebral column. See Workup for more detail. [emedicine.com]

bone pain, muscle pain, headache, fatigue, and loss of weight.[1] Cause[edit] As of 2017 the cause of the disease was not understood.[1] Diagnosis[edit] Blood tests show [en.wikipedia.org]

(exanthema attacks go parallel with the periodic fever), fatigue and tiredness, arthralgia, arthritides and bone pain (especially tibia and pelvic bone). [altmeyers.org]

Fungal Osteomyelitis

Osteomyelitis is a painful bone infection. It usually goes away if treated early with antibiotics. If not, it can cause permanent damage. What is osteomyelitis? [nhs.uk]

A nuclear imaging method to evaluate any degenerative and/or arthritic changes in the joints; to detect bone diseases and tumors; to determine the cause of bone pain or inflammation [chop.edu]

bone Long-term outlook for a child with osteomyelitis In most cases, the infection is cured with antibiotic medication. [stanfordchildrens.org]

Gaucher Disease

Clinically apparent bony involvement, which occurs in more than 20% of patients with Gaucher disease, can present as bone pain or pathologic fractures. [emedicine.medscape.com]

(joint pain, bone fractures, etc). [symptoma.com]

Medicines may be given to: Replace the missing GBA (enzyme replacement therapy) to help reduce spleen size, bone pain, and improve thrombocytopenia. [nlm.nih.gov]

Osteosarcoma

How bone pain is experienced may vary. [healthline.com]

Herein, we presented a 50-year-old man patient who visited hospital due to local bone pain in the left leg. He was initially diagnosed with osteoblastic osteosarcoma. [ncbi.nlm.nih.gov]

Symptoms of osteosarcoma can mimic growing pains — pain in the legs caused by normal bone growth. However, growing pains typically stop during the early teenage years. [healthline.com]

Osteomyelitis of the Tibia

Bone lesion biopsy (Medical Encyclopedia) Bone pain or tenderness (Medical Encyclopedia) Disseminated tuberculosis (Medical Encyclopedia) Osteomyelitis (Medical Encyclopedia [icdlist.com]

Acute osteomyelitis is suspected in patients with localized peripheral bone pain, fever, and malaise or with localized refractory vertebral pain, particularly in patients [merckmanuals.com]

Osteomyelitis is a painful bone infection. It usually goes away if treated early with antibiotics. If not, it can cause permanent damage. What is osteomyelitis? [nhs.uk]

Chronic Pyogenic Osteomyelitis

This may be followed by an increase in fever (104-105 degrees Fahrenheit), deep localized bone pain, chills, sweating, swelling and painful or limited movement of the nearby [rarediseases.org]

For this reason, it is very important to seek medical attention whenever the bone pain worsens and presents itself along with fever. [ic.steadyhealth.com]

The child is toxic and ill and complains of bone pain. [www0.sun.ac.za]

Paget Disease of the Bone

Bisphosphonate therapy is primarily indicated for patients who have bone pain arising from increased metabolic activity in affected bones. [ncbi.nlm.nih.gov]

They are thought to reduce bone turnover, improve bone pain, promote healing of osteolytic lesions and restore normal bone histology [ 1 ]. [patient.info]

There was rapid complete relief of bone pain accompanied by biochemical improvement or normalization in all cases. [ncbi.nlm.nih.gov]

Familial Paget Disease of Bone

They are thought to reduce bone turnover, improve bone pain, promote healing of osteolytic lesions and restore normal bone histology [ 1 ]. [patient.info]

Most patients remain asymptomatic for prolonged periods of time; few suffer from bone pain, joint pain secondary to osteoarthritis, fractures due to bone instability, or skeletal [symptoma.com]

When symptoms occur, the most common complaints are bone pain and/or deformity. [patient.info]

Osteomalacia

[…] are achy bone pain and skeletal muscle weakness, fractures, and other complications ( TABLE 1 ). 1,2 Osteomalacia is most often caused by a vitamin D deficiency. 2 Even though [uspharmacist.com]

Here, we present the case of a 31-year-old man who has been suffering from generalised bone pains and a spine deformity that led to loss of height. [ncbi.nlm.nih.gov]

We report a 39-year-old male who presented with polydipsia, polyuria, and multiple bone pain. [ncbi.nlm.nih.gov]

Parathyroid Adenoma

We report one such incidence of a 14 years old girl who presented with bone pains short stature, and generalized muscle wasting. [ncbi.nlm.nih.gov]

Introduction Adenomas of the parathyroid gland typically present with symptoms of hyperparathyroidism, manifested by fatigue, bone pain, abdominal pain, weakness, dyspepsia [ncbi.nlm.nih.gov]

We report a case of a 70-year-old man with a history of total parathyroidectomy and thymectomy presented with a lack of appetite, nausea, and generalized bone pain, polydipsia [ncbi.nlm.nih.gov]

Primary Myelofibrosis

Painful episodes of splenic infarction may occur. The patient becomes cachectic and may experience severe bone pain, especially in the upper legs. [accessmedicine.mhmedical.com]

Involved field radiotherapy is most useful for post-splenectomy hepatomegaly, non-hepatosplenic EMH, PMF-associated pulmonary hypertension, and extremity bone pain. [ncbi.nlm.nih.gov]

Osteosclerosis, hypertrophic osteoarthropathy and periostitis: may cause severe joint and bone pain. [patient.info]

Metatarsal Stress Fracture

How it affects your running The pain from a metatarsal stress fracture is usually felt on the top of the foot, over the affected metatarsal bone. [runnersrescue.com]

The pain from a metatarsal stress fracture is usually felt on the top of the foot, over the affected metatarsal bone. [jointpaininfo.com]

Other causes of forefoot pain • Morton's neuroma (benign tumor of a nerve running between the metatarsals) • Metatarsalgia (painful and inflammation of the metatarsal bones [njfootdoc.com]

Leukemia

So, it's more generalized bone pain. [khanacademy.org]

pain Paleness Pinhead-size red spots on the skin Weight loss How Is Leukemia Treated? [hematology.org]

The child may also have bone pain. Spleen and abdomen may be enlarged and are tender to the touch. [nationwidechildrens.org]

Familial Hypophosphatemia

Bone pain, fatigue, myopathy, as well as growth and dental abnormalities are usually encountered, whereas cardiac and pulmonary failure may ensue in severe cases. [symptoma.com]

[…] of the spine (termed scoliosis) Hearing loss Frequent muscle cramps Bone pain with frequent fractures due to weak bones. [dovemed.com]

More severe cases can present with neurological complaints (altered speech, confusion, seizures, hearing impairment), bone pain, poor teeth status, and fatigue. [symptoma.com]

Carcinoma of the Prostate

pain, weakness, and fractures. [casereports.bmj.com]

If you have bone pain or doctors think cancer may have spread to your bones, brain, or spinal cord, doctors will do: Bone scan Your doctors will work with you to decide which [merckmanuals.com]

}uphs.upenn.edu Abstract Tumour-induced osteomalacia (TIO), or oncogenic osteomalacia, is a paraneoplastic syndrome marked by hypophosphataemia, renal phosphate wasting, bone [casereports.bmj.com]

X-Linked Hypophosphatemia

Patients with X-linked hypophosphatemia have short stature, rickets, bone pain and dental abscesses. [ncbi.nlm.nih.gov]

In adulthood, therapy is usually continued in symptomatic patients and generally aims at reducing bone pain. [orpha.net]

Current therapy is oral phosphate and vitamin D which effectively treats the rickets and bone pain but does not adequately improve short stature. [ncbi.nlm.nih.gov]

Familial Myelofibrosis

It can be used to treat an enlarged spleen, bone pain or tumours that develop outside of the bone marrow. [cancer.ca]

pain What causes MF? [canadianmpnnetwork.ca]

In turn, this causes the liver and spleen to become enlarged and creates some of the symptoms such as abdominal pain, feeling full, weight loss, fatigue, itching, bone pain [cancercare.org]

Neuroblastoma

The most frequent manifestations were: fever (25%), abdominal pain (22%), abdominal mass (19%), and bone pain (19%). [ncbi.nlm.nih.gov]

Many symptoms of neuroblastoma are caused by pressure from the tumor or bone pain if the cancer has spread to the bones. [cancer.net]

Bone pain and limp can be interpreted as synovitis of the hip. [orpha.net]

Hypophosphatasia

Fractures and bone pain usually characterise the adult form. A 9-year-old girl was referred for repetitive fractures after minimal trauma. [ncbi.nlm.nih.gov]

Conclusion: We report a novel mutation of ALPL presenting with short stature and bone pain. [abstracts.eurospe.org]

Childhood form is caractherized by short stature, premature loss of decidous teeth and diffuse bone pain associated with a pathological bone fracture in the past. [ncbi.nlm.nih.gov]

Osteogenesis Imperfecta

Bone pain In one trial, bone pain was assessed using the Wong‐Baker FACES at baseline, 6 and 12 months and did not identify a clear increase in bone pain compared to baseline [doi.org]

Bone pain ameliorated just after the first cycle of pamidronate, while the activity and mobility increased quickly. [ncbi.nlm.nih.gov]

Multiple fractures can lead to permanent bone deformities, bowed bones, and bone pain. Frequently, scoliosis (spine curvature) and short stature are present. [bonehealth.wustl.edu]

Systemic Mastocytosis

[…] patients reported improvement in bone pain after bisphosphonate treatment. [ard.bmj.com]

Nausea, stomach pain, diarrhea and vomiting. Bone pain. Flushing (when skin all over the body turns red). A drop in blood pressure. Fainting. [my.clevelandclinic.org]

Fig. 7: This 29 year old Indian woman presented with bone pain and lethargy. Radiographically all her bones have increased density with a blurred trabecular pattern. [healio.com]

Ewing Sarcoma

Most common symptoms reported: Localised pain: bone pain; may come and go and vary in its intensity. [web.archive.org]

Clinical presentation is usually dominated by local bone pain and a mass. [ncbi.nlm.nih.gov]

Symptoms Signs and symptoms of Ewing sarcoma include: Pain, swelling or tenderness near the affected area Bone pain Unexplained tiredness Fever with no known cause Losing [mayoclinic.org]

Osteoid Osteoma

Osteoid osteomas are benign bone lesions that present with bone pain in children and young adults. [ncbi.nlm.nih.gov]

OBJECTIVES: To assess the efficacy of bisphosphonate therapy on bone pain in patients with osteoid osteoma (OO) (main objective), and to describe bisphosphonate-induced changes [ncbi.nlm.nih.gov]

CONCLUSION Osteoid osteoma is a relatively common benign bone lesion in children and young adults that can present with nontraumatic bone pain. [appliedradiology.com]