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527 Possible Causes for Bone Pain, Failure to Thrive, Tooth Loss

  • Hypophosphatasia

    Fractures and bone pain usually characterise the adult form. A 9-year-old girl was referred for repetitive fractures after minimal trauma.[ncbi.nlm.nih.gov] The descriptions include both the manifestations of the disorder and the subsequent patterns of tooth loss.[ncbi.nlm.nih.gov] The infantile case presented with failure to thrive, hypotonia, and radiologic rickets at 4 months old.[ncbi.nlm.nih.gov]

  • Primary Hyperoxaluria

    This can lead to bone pain; vision loss; tingling, numbness, or pain in the extremities; enlargement of the liver and spleen; and problems with the electrical system of the[counsyl.com] The term "infantile oxalosis" is used to describe the triad of anemia, failure to thrive, and acidosis in infants with this condition.[symptoma.com] He presented bone pain with worsening of his general state. On physical examination, no organomegaly was detected.[bmcclinpathol.biomedcentral.com]

  • Vitamin D Deficiency

    METHODS: Patients with leg pain, defined as local pain and tenderness over tibial bones for 6 weeks were consecutively selected.[ncbi.nlm.nih.gov] […] inflammatory bone loss, following an infectious breach of the alveolar cortical bone, and it may result in tooth loss.[doi.org] She presented with fractures during the first year-of-life followed by bone deformities, delayed development, failure-to-thrive, and pneumonias.[ncbi.nlm.nih.gov]

  • Celiac Disease

    In patients with bone pain, non traumatic fractures and muscle weakness, osteomalacia should be kept in mind and proper diagnostic work-up should be performed to identify[ncbi.nlm.nih.gov] We found non-specific tooth wear, characterized by loss of the mineralized tissue of the teeth, in 9 patients (18.3%) and in 3 (5.9%) controls ( p 0.05). (4) Conclusion: Recurrent[ncbi.nlm.nih.gov] In young children, gastrointestinal presentations are common and include chronic diarrhea, failure to thrive, and abdominal distention; however, extraintestinal manifestations[doi.org]

  • Langerhans-Cell Histiocytosis

    Well-localised bone pain is a common presenting symptom, with pain during both activity and rest. Lesions are lytic.[patient.co.uk] […] development abnormalities, and premature tooth loss.[ncbi.nlm.nih.gov] We describe a 16-month-old girl who initially presented with bilious vomiting, failure to thrive and a rash.[ncbi.nlm.nih.gov]

  • Gaucher Disease

    Clinically apparent bony involvement, which occurs in more than 20% of patients with Gaucher disease, can present as bone pain or pathologic fractures.[emedicine.medscape.com] […] canal displacement (18.9%), cortical perforation, maxillary sinus obliteration, and tooth displacement (10.8%).[ncbi.nlm.nih.gov] Failure to thrive and stridor (due to laryngospasm) are also common.[symptoma.com]

  • Paget Disease of the Bone Type 5

    Paget disease is asymptomatic in 70-90%of persons.Affected individuals experience various symptoms: Bone pain (it is the most common symptom) Secondary osteoarthritis (when[drthindhomeopathy.com] […] of teeth Early tooth loss Loss of teeth Premature teeth loss Premature tooth loss [ more ] 0006480 Progressive Worsens with time 0003676 Sensorineural hearing impairment[rarediseases.info.nih.gov] Clinical manifestations present from early infancy and include: skeletal deformity and failure to thrive followed by skull enlargement, difficulty in walking, progressive[iofbonehealth.org]

  • Osteoporosis

    Transient osteoporosis of the hip (TOH) is characterized by bone pain, osteopenia, and bone marrow edema in the absence of trauma.[ncbi.nlm.nih.gov] loss.[web.archive.org] Other complications include hypercalcemia, irritability, poor feeding, failure to thrive, hypotonia, and more rarely vitamin B 6 -dependent seizures (see Management ).[web.archive.org]

  • Mucopolysaccharidosis

    Pelvic radiography showed multiple soft-tissue masses and some bone erosion.[en.wikipedia.org] Affected children may also have an abnormally large head (macrocephaly), a short neck and broad chest, delayed tooth eruption, progressive hearing loss, and enlargement of[rarediseases.org] […] multiorgan deterioration that includes hepatosplenomegaly, dysostosis multiplex, short stature, coarse facial features, corneal clouding, joint contractures, umbilical hernias, failure[surgicalneurologyint.com]

  • Osteomalacia

    […] are achy bone pain and skeletal muscle weakness, fractures, and other complications ( TABLE 1 ). 1,2 Osteomalacia is most often caused by a vitamin D deficiency. 2 Even though[uspharmacist.com] An orthopantomogram was done which showed generalized sever bone loss (up to the apex of tooth), impacted lower left second premolar along with thinning of mandibular cortex[ncbi.nlm.nih.gov] Rickets Clinical feature General Failure to thrive Apathetic , listless, irritable Shorter, lower body weight and anemic Excessive sweating particularly at hand & face[slideshare.net]

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