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1,352 Possible Causes for Bone Pain, Pancytopenia

  • Multiple Myeloma

    Here we report a patient with MM presenting with renal failure, anemia, and bone pain. The renal biopsy showed DDD.[ncbi.nlm.nih.gov] Haematological tests revealed severe anaemia with pancytopenia, which prompted further investigations including a bone marrow biopsy confirming a diagnosis of multiple myeloma[ncbi.nlm.nih.gov] The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).[orpha.net]

  • Chronic Myeloid Leukemia

    They include: Weakness Fatigue Night sweats Weight loss Fever Bone pain (caused by leukemia cells spreading from the marrow cavity to the surface of the bone or into the joint[cancer.org] We present a case of 29-year-old white male farmer, with chronic myeloid leukemia treated with imatinib who developed significant pancytopenia, leading to discontinuation[ncbi.nlm.nih.gov] As a result of bone marrow infiltration, one or all series are suppressed, generating pancytopenia (anemia, neutropenia and thrombocytopenia).[pathologyatlas.ro]

  • Systemic Mastocytosis

    […] patients reported improvement in bone pain after bisphosphonate treatment.[ard.bmj.com] The disease progressed rapidly and severe pancytopenia and recurrent upper gastrointestinal bleeding became the dominant problem.[ncbi.nlm.nih.gov] […] organomegaly and organ dysfunction, impairment of hematopoietic function (which may result in disruption of the blood count ranging from isolated cytopenia to more or less marked pancytopenia[orpha.net]

  • Primary Myelofibrosis

    Involved field radiotherapy is most useful for post-splenectomy hepatomegaly, non-hepatosplenic EMH, PMF-associated pulmonary hypertension and extremity bone pain. Am.[ncbi.nlm.nih.gov] Primary myelofibrosis is a unique entity among BCR-ABL-negative myeloproliferative diseases, manifesting as bone marrow fibrosis and pancytopenia.[ncbi.nlm.nih.gov] […] and joint pain) Gout For a small number of patients, MF can transform to acute myeloid leukemia (AML), a serious blood and bone marrow cancer.[mpnresearchfoundation.org]

  • Leukemia

    So, it's more generalized bone pain.[khanacademy.org] Bone marrow examination Histochemical studies, cytogenetics, immunophenotyping, and molecular biology studies Imaging CBC and peripheral smear are the first tests done; pancytopenia[merckmanuals.com] […] familial exposure to radiation during cancer treatment and strategies to help limit incidental contact with potentially harmful byproducts. more » A 47-Year-Old Woman with Pancytopenia[cancertherapyadvisor.com]

  • Promyelocytic Leukemia

    Transcript: Ehab Atallah, MD: Patients with APL usually present with bleeding or sometimes they present with feeling tired and having bone pain.[onclive.com] We report a case of recurrent pancytopenia resulting from maintenance chemotherapy in a patient with acute promyelocytic leukemia and two pharmacogenetic mutations, namely[ncbi.nlm.nih.gov] pain from a build up of cancer cells in the bone marrow Swollen glands from a build up of cancer cells in the lymph nodes Abdominal pain from a swollen spleen or liver Some[lundbeck.com]

  • Acute Leukemia

    Herein we present a standard risk pediatric acute lymphobiastic leukemia patient who developed myalgia, bone pain, bone marrow aplasia and sinusoidal obstruction syndrome[ncbi.nlm.nih.gov] Pancytopenia in her secondary MF phase responded well to the therapy of corticosteroids, which indicated that the immune mechanism was involved in the pathogenesis of MF.[ncbi.nlm.nih.gov] pain, sometimes associated with swelling of the joints The signs and symptoms of ALL can be the same as more common children’s illnesses and many children are treated for[childrensoncologygroup.org]

  • T-cell Acute Lymphoblastic Leukemia

    There was no history of cough, swelling anywhere else in the body, bone pain, abdominal distention, bleeding, blood transfusion, contact with tuberculosis, redness, trauma[henrypublishinggroups.com] The patient was a 16-year-old boy who presented with septic shock and pancytopenia, likely precipitated by an acute parvovirus B19 infection.[ncbi.nlm.nih.gov] Blood clots Palpable lymphadenopathy Symptoms related to a large mediastinal mass (eg, shortness of breath), particularly with T-cell lymphoblastic leukemia/lymphoma (T-ALL) Bone[emedicine.medscape.com]

  • Myeloproliferative Disease

    Symptoms Signs  Fatigue  Malaise  Early satiety  Weight loss  Fever  Abdominal painBone pain  Pruritis  Splenomegaly  Abnormal blood counts  Abnormal peripheral[slideshare.net] Four years later, at the age of 16, her brother was diagnosed as having acute myelofibrosis, and some months afterwards he died from fulminant pneumonia coincidently with pancytopenia[ncbi.nlm.nih.gov] Waldenstrom's Macroglobulinemia Plasma Cell Dyscrasias (PCDs) -Multiple Myeloma * Symptoms -Unexplained: * bone pain (back, thorax) * renal failure * recurrent bacterial infections[quizlet.com]

  • B-Precursor Acute Lymphoblastic Leukemia

    We present the case of a 9-year-old girl from northwestern Greece admitted to our Hospital because of malaise, low-grade fever, intermittent hip joint pain, anemia, leukopenia[ncbi.nlm.nih.gov] B-precursor acute lymphoblastic leukemia is diagnosed with a standard complete blood count (CBC), which will reveal pancytopenia.[symptoma.com] […] in the bones or stomach pain or a feeling of fullness below the ribs painless lumps in the neck, underarm, stomach, or groin tests that examine the blood and bone marrow[icd10data.com]

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