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64 Possible Causes for Bone Spicule Pigment in Periphery

  • Retinitis Pigmentosa

    Fundus examination (Figure 2 ) reveals the presence of bone spicule-shaped pigment deposits in the mid periphery, along with atrophy of the retina.[ojrd.com] Figure 2 Fundus of patient with retinitis pigmentosa, mid stage (Bone spicule-shaped pigment deposits are present in the mid periphery along with retinal atrophy, while the[ojrd.com] Indeed, visual field testing shows mild periphery scotomas that tend to enlarge towards extreme periphery and macular area.[ojrd.com]

  • Foveal Retinoschisis

    Anterior and intermediate segments were normal with mild cataract, but both fundus showed atrophy and bone spicule pigmentation in the periphery.[euretina.org]

  • Pseudoxanthoma Elasticum

    […] with pigment migration and bone spicules at the retinal level. ( h ) Case 4: waxy appearance of both optic nerve heads and drusen, angioid streaks, a fibroglial scar on the[iovs.arvojournals.org] […] vision in the left eye; no evidence of choroidal neovascularization; a temporal appearance of peau d'orange; punched-out lesions in the midperiphery; RPE atrophy in the periphery[iovs.arvojournals.org]

  • Senior-Løken Syndrome

    Bone spicule pigmentation can be seen in the periphery, the retinal vessels are attenuated, the ERG is undetectable, and there may be temporal pallor of the optic discs.[disorders.eyes.arizona.edu]

  • Degenerative Disorder

    Fundus examination (Figure 2 ) reveals the presence of bone spicule-shaped pigment deposits in the mid periphery, along with atrophy of the retina.[doi.org] Figure 2 Fundus of patient with retinitis pigmentosa, mid stage (Bone spicule-shaped pigment deposits are present in the mid periphery along with retinal atrophy, while the[doi.org] Indeed, visual field testing shows mild periphery scotomas that tend to enlarge towards extreme periphery and macular area.[doi.org]

  • Pigmented Paravenous Retinochoroidal Atrophy

    Figure 5: Color fundus photo of the superior periphery of the left eye. Note areas of bone-spicule pigmentation and atrophy along retinal veins.[westcoastretina.com] Figure 4: Color fundus photos of the temporal periphery of the right eye. Note the areas of bone-spicule pigment clumping and atrophy along multiple retinal veins.[westcoastretina.com] In the periphery there was vitreous traction associated with the pigment changes (Figure 6) without retinal tear or subretinal fluid.[westcoastretina.com]

  • Retinitis pigmentosa 44

    In common with other forms of RP, a similar pattern of field loss, presence of cataracts in some cases, and typical bone spicule pigment around the periphery was observed[jci.org] Bone spicule pigmentation in the mid-periphery was the most common variant seen in more than half of the patients while 35 (36.5%) had maculopathy ( Table 2 ).[dovepress.com] A natural history study from our institution defined the phenotype as bone-spicule pigmentation or atrophy in the near mid-periphery corresponding to an annular scotoma from[mdpi.com]

  • Fuchs' Heterochromic Iridocyclitis

    Retinal hyperpigmentation in bone spicules at mid-periphery. Pigment clumping in macular area. Extensive atrophy of retinal pigment epithelium.[journalretinavitreous.biomedcentral.com] […] dust in the vitreous gel, hyper and hypopigmented retinal pigment epithelium (RPE) changes forming ‘bone spicules’ scattered in the posterior pole up to the equator and pigment[journalretinavitreous.biomedcentral.com]

  • Retinitis pigmentosa 40

    Retinal hyperpigmentation in bone spicules at mid-periphery. Pigment clumping in macular area. Extensive atrophy of retinal pigment epithelium.[journalretinavitreous.biomedcentral.com] In more advanced stages patients show retinal arteriolar attenuation, bone spicule pigmentation around the periphery in most cases, and waxy pallor of the optic discs.[ncbi.nlm.nih.gov] Most patients show intraretinal pigment in a bone spicule configuration around the fundus periphery, for which this condition was named.[pnas.org]

  • Bothnia Retinal Dystrophy

    Fundus examination showed a bilateral round atrophy of the macula, narrowed retinal vessels, atrophic optic discs, and many bone spicule pigment deposits in the retinal periphery[molvis.org] spicule pigment deposits in the retinal periphery, and narrowing of retinal vessels without atrophy of the optic disc.[molvis.org] […] with no light perception, while the contralateral eye had decreased visual acuity at 0.3 (in part due to a cataract as shown by the blurred fundus image [ Figure 2G ]), bone[molvis.org]

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