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676 Possible Causes for Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium, Mutation in the TTLL5 Gene, Possibly Parkinsonism

  • Neuronal Ceroid Lipofuscinosis 4B

    Infantile and late-infantile retinal findings include fine retinal pigment epithelium pigment atrophy with no bone spicule changes and disk pallor.[journals.lww.com] Juvenile retinal findings include macular retinal pigment epithelium atrophy and pigment stippling ( 50%), epiretinal membrane (33%), bull’s eye maculopathy (25%), and peripheral[journals.lww.com] bone spicules (46%) and variable disk pallor.[journals.lww.com]

    Missing: Mutation in the TTLL5 Gene
  • Overeating

    But that's not to say it's not possible. How often does this side effect occur?[web.archive.org] A common dosage for restless legs is 0.125 milligrams (mg) a day, while the daily dosage for Parkinson's is more like 4.5 mg.[web.archive.org] A study of 529 people taking pramipexole for Parkinson's symptoms revealed that 1.5 percent of them had developed compulsive gambling behaviors.[web.archive.org]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Cone Rod Dystrophy
    Missing: Possibly Parkinsonism
  • Urinary Tract Disease

    Some possible causes of neurogenic bladder include: diabetes accidents that cause trauma to the brain or spinal cord nerve problems such as multiple sclerosis, strokes, or[healthywomen.org] Parkinsonism congenital nerve problems such as spina bifida Primary effects of neurogenic bladder are: urine leakage, when muscles holding the urine do not get the message[healthywomen.org]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Constipation

    IBS-like bowel symptoms in PD and their possible connection to other non-motor symptoms and faecal microbiota were assessed.[ncbi.nlm.nih.gov] METHODS: This case-control study compared 74 PD patients with 75 controls without any signs of parkinsonism or potential premotor symptoms.[ncbi.nlm.nih.gov]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Insomnia

    ’s Disease) Lung disease Cardiovascular disease Arthritis If possible, trying to treat some pre-existing factors can improve the level of severity of insomnia experienced.[sleepdex.org] Kidney disease or bladder dysfunction Chronic mood disorders (Depression and/or anxiety) Gastrointestinal Reflux Disease (GERD) Neurological Disorders (Alzheimer’s Disease, Parkinson’s[sleepdex.org]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Acne Vulgaris

    , Parkinson's disease, and liver damage.[doi.org] The possible side effects and consequences of excessive nicotinamide exposure are reviewed, including suggestions nicotinamide might have a role in the development of diabetes[doi.org]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Orthostatic Hypotension

    Low blood pressure has many possible causes beyond Parkinson's disease.[michaeljfox.org] These findings suggest that clinically asymptomatic orthostatic hypotension in Parkinson's disease patients may acutely worsen neuropsychological performances with possible[ncbi.nlm.nih.gov] Patients with autonomic symptoms or signs require further evaluation for diabetes, Parkinson disease, and possibly multiple system atrophy and pure autonomic failure.[msdmanuals.com]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Parkinson's Disease

    It is not possible to prevent Parkinson's disease, but research has shown that some lifelong habits may help to reduce the risk.[medicalnewstoday.com] , made possible by a grant from the National Parkinson Foundation. For more resources, please click here . Partners[danceforparkinsons.org] Autoimmune factors : Scientists reported in JAMA in 2017 that they had found evidence of a possible genetic link between Parkinson's disease and autoimmune conditions, such[medicalnewstoday.com]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene
  • Restless Legs Syndrome

    Dizziness, fatigue and sleepiness are among the possible side effects.[sharecare.com] But what about the other possibility? Do patients with Parkinson’s Disease have RLS, and how often?[apdaparkinson.org] Novel mutations, pseudo-dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism.[dx.doi.org]

    Missing: Bone-Spicule Pigmentation in Peripheral Retinal Pigment Epithelium Mutation in the TTLL5 Gene