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61 Possible Causes for Bone Spicule Pigmentation in Periphery

  • Retinitis Pigmentosa

    Fundus examination (Figure 2 ) reveals the presence of bone spicule-shaped pigment deposits in the mid periphery, along with atrophy of the retina.[ojrd.com] Figure 2 Fundus of patient with retinitis pigmentosa, mid stage (Bone spicule-shaped pigment deposits are present in the mid periphery along with retinal atrophy, while the[ojrd.com] Indeed, visual field testing shows mild periphery scotomas that tend to enlarge towards extreme periphery and macular area.[ojrd.com]

  • Pseudoxanthoma Elasticum

    […] with pigment migration and bone spicules at the retinal level. ( h ) Case 4: waxy appearance of both optic nerve heads and drusen, angioid streaks, a fibroglial scar on the[iovs.arvojournals.org] […] vision in the left eye; no evidence of choroidal neovascularization; a temporal appearance of peau d'orange; punched-out lesions in the midperiphery; RPE atrophy in the periphery[iovs.arvojournals.org]

  • Foveal Retinoschisis

    Anterior and intermediate segments were normal with mild cataract, but both fundus showed atrophy and bone spicule pigmentation in the periphery.[euretina.org]

  • Degenerative Disorder

    Fundus examination (Figure 2 ) reveals the presence of bone spicule-shaped pigment deposits in the mid periphery, along with atrophy of the retina.[doi.org] Figure 2 Fundus of patient with retinitis pigmentosa, mid stage (Bone spicule-shaped pigment deposits are present in the mid periphery along with retinal atrophy, while the[doi.org] Indeed, visual field testing shows mild periphery scotomas that tend to enlarge towards extreme periphery and macular area.[doi.org]

  • Senior Loken Syndrome

    Bone spicule pigmentation can be seen in the periphery, the retinal vessels are attenuated, the ERG is undetectable, and there may be temporal pallor of the optic discs.[disorders.eyes.arizona.edu]

  • Fuchs' Heterochromic Iridocyclitis

    Retinal hyperpigmentation in bone spicules at mid-periphery. Pigment clumping in macular area. Extensive atrophy of retinal pigment epithelium.[journalretinavitreous.biomedcentral.com] […] dust in the vitreous gel, hyper and hypopigmented retinal pigment epithelium (RPE) changes forming ‘bone spicules’ scattered in the posterior pole up to the equator and pigment[journalretinavitreous.biomedcentral.com]

  • Pigmented Paravenous Retinochoroidal Atrophy

    Figure 5: Color fundus photo of the superior periphery of the left eye. Note areas of bone-spicule pigmentation and atrophy along retinal veins.[westcoastretina.com] Figure 4: Color fundus photos of the temporal periphery of the right eye. Note the areas of bone-spicule pigment clumping and atrophy along multiple retinal veins.[westcoastretina.com] In the periphery there was vitreous traction associated with the pigment changes (Figure 6) without retinal tear or subretinal fluid.[westcoastretina.com]

  • Retinitis pigmentosa 40

    Retinal hyperpigmentation in bone spicules at mid-periphery. Pigment clumping in macular area. Extensive atrophy of retinal pigment epithelium.[journalretinavitreous.biomedcentral.com] In more advanced stages patients show retinal arteriolar attenuation, bone spicule pigmentation around the periphery in most cases, and waxy pallor of the optic discs.[ncbi.nlm.nih.gov] Most patients show intraretinal pigment in a bone spicule configuration around the fundus periphery, for which this condition was named.[pnas.org]

  • Retinitis pigmentosa 44

    In common with other forms of RP, a similar pattern of field loss, presence of cataracts in some cases, and typical bone spicule pigment around the periphery was observed[jci.org] Bone spicule pigmentation in the mid-periphery was the most common variant seen in more than half of the patients while 35 (36.5%) had maculopathy ( Table 2 ).[dovepress.com] A natural history study from our institution defined the phenotype as bone-spicule pigmentation or atrophy in the near mid-periphery corresponding to an annular scotoma from[mdpi.com]

  • Retinitis Pigmentosa 11

    In common with other forms of RP, a similar pattern of field loss, presence of cataracts in some cases, and typical bone spicule pigment around the periphery was observed[jci.org] Bone spicule pigmentation in the mid-periphery was the most common variant seen in more than half of the patients while 35 (36.5%) had maculopathy ( Table 2 ).[dovepress.com] All patients showed characteristic retinal bone spicule pigmentation.[jamanetwork.com]

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