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472 Possible Causes for Bone Spicules

  • Usher Syndrome Type 1K

    The fundoscopic finding of both eyes showed typical pigmentary degeneration with multiple bone spicule pigmentations in over the entire retina, attenuated retinal vessels,[] Temporal bone computed tomography and magnetic resonance imaging showed no specific findings.[] On ophthalmologic examinations, the lens and the cornea were intact, but the fundoscopic examination revealed bony spicule pigmentation with attenuated retinal vessels in[]

  • Nephronophthisis

    Bone spicule pigmentation can be seen in the periphery, the retinal vessels are attenuated, the ERG is undetectable, and there may be temporal pallor of the optic discs.[]

  • Usher Syndrome Type 3B

    These include pigment dispersion, which means that some parts appear lighter than others, followed by "bone spicules" which are little jagged spots.[] The optic nerve (arrow) looks very pale, the vessels (stars) are very thin and there is characteristic pigment, called bone spicules (double arrows).[] […] of bone.[]

  • Retinitis Pigmentosa with Situs Inversus

    Fundus examination showed bone spicule formation, pigmentation, arteriolar attenuation and optic atrophy in both eyes [Figure:1a].[] Fundus examination reveals bone spicule pigment deposits, attenuated retinal vessels, retinal atrophy and waxy optic nerve pallor.[]

  • Macular Degeneration, Early Onset

    No peripheral atrophy with bone spicule nor optic nerve atrophy were observed.[]

  • Bardet-Biedl Syndrome 2

    The fundus picture was an atypical retinitis pigmentosa with macular pigments previous to any bone spicules.[] There were salt-and-pepper changes in the midperiphery accompanied by bone spicule–like pigmentation.[] Early changes are more characteristic of atrophy with a paucity of pigment but later the bone spicule pattern of hyperpigmentation appears.[]

  • Retinitis Pigmentosa 7

    The macula looks smooth and normal; however, the retinal vessels are attenuated and there are bone spicules throughout the periphery. OS: Vertical C/D ratio is 0.0.[] LCA is characterized by night blindness, constricted visual fields, narrowed vessels, bone-spicule pigmentation in midperiphery of retina, pigment deposits in macular region[] Tags: bone spicules , Chihuly , fundoscopic image , glass , neural plasticity , neural remodeling , pigmented bone spicules , retina , retinal plasticity , retinal remodeling[]

  • Extraskeletal Myxoid Chondrosarcoma

    (SKB) Clear cells, giant cells and bone spicules. (SKB) The lesion also had areas of more conventional chondrosarcoma.[] (SKB) Clear cells, giant cells and bone spicules. (SKB) Somewhat hemangiopericytomatous vascular pattern with giant cells.[] […] matrix Areas with osteoclast-type giant cells mixed with small trabeculae of reactive bone May contain conventional low-grade chondrosarcoma May have secondary aneurysmal bone[]

  • Retinal Macular Dystrophy Type 2

    The classic fundus appears with dark pigmentary clumps in the periphery and perivenous areas (bone spicules).[] Fundus findings range from a salt and pepper appearance to frank bone spicules, and macular changes with foveomacular hyperfluorescence on fluorescein angiography.[] At later stages, the fundus picture discloses a pale optic disc, peripheral bone spicule-like hyperpigmentation and generalized atrophic changes of the peripheral retina.[]

  • Gordon Holmes Syndrome

    spicules.[] Clinical Characteristics Ocular Features: The retinal pigment epithelium changes may be seen as early as the first decade of life with pigment deposition resembling bone spicules[] Hypogonadism Clinical Characteristics Ocular Features: The retinal pigment epithelium changes may be seen as early as the first decade of life with pigment deposition resembling bone[]

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