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42 Possible Causes for Bone Spicules, Knee Pain, Multiple Lytic Bone Lesions

  • Osteosarcoma

    A characteristic ‘sun-ray’ effect of bone spicules is often visible on X-ray.[] pain.[] Wick: Foot osteoblastic Low grade sclerosing type Osteoblastic type with blue spiculated bone With infiltrative medullary growth Images hosted on other servers: Osteoblastic[]

  • Multiple Myeloma

    This fluid is predominantly blood, but mixed in are bone marrow particles (spicules) which are then spread onto glass slides, stained, and examined by hematologists and pathologists[] An increased incidence of multiple lytic bone lesions ( P .001) was observed in LCO patients compared with IgG and IgA patients but was not apparent in bone pain or fractures[] CASE REPORT A 56-year-old man with multiple myeloma presented with chronic polyarticular pain and swelling.[]

  • Ewing's Sarcoma

    Uncommon features included epiphyseal involvement (4%), sclerosis (4%), expansion of bone (8%), sunray spiculation (10%), calcification in soft tissue (8%), saucerization[] Patellar tumors occur infrequently and represent an uncommon etiology of anterior knee pain.[] It may be spiculated and interrupted - sometimes there is a Codman's triangle.[]

  • Malignant Bone Neoplasm

    Identical nuclei in both types Multiple myeloma - lytic bone lesion Multiple myeloma - numerous punched out lesions Multiple myeloma - increased plasma cells multiple myeloma[] Sunburst and hair-on-end periosteal formations also are associated with aggressive bone tumors and are radiating spicules of periosteal bone.[] Chondroblastoma Rare, normally in epiphysis of long bones - eg, the hip, shoulder and knee.[]

  • Bone Tumor

    OSTEOBLASTOMA Definition: - Benign bone forming neoplasm producing woven bone spicules bordered by prominent osteoblasts (osteoid osteoma measuring more than 2.0 cm) Epdemiology[] Multiple Myeloma: multiple lytic lesions in the humerus Multiple Myeloma Multiple myeloma must be included in the differential diagnosis of any lytic bone lesion, whether[] Condition Anterior Knee Pain and Runner's Knee Learn about anterior knee pain, or runner's knee.[]

  • Juxtacortical Osteosarcoma

    Periosteal osteosarcoma is also found of the surface of bone, but has a more spiculed appearance and may appear more aggressive.[] Multiple lytic bone lesions ‘FEEMHI’ – Fibrous dysplasia, Enchondroma, EG, Mets/Myeloma, Hyperparathyriodism, Infection.[] Because of the location in the popliteal fossa, the patient may note inability to flex the knee.[]

  • Fibrosarcoma

    The lesion usually has no matrix mineralization, but may have areas of sequestered bone.[] How would you explain the cause of your knee pain? How long has your knee pain been going on? How severe is your knee pain? Is your knee pain getting better or worse?[] Since most knee and other joint pains are not associated with a tumor, the key is to identify symptoms that warrant further evaluation.[]

  • Osteoblastoma

    Benign osteoblastoma is a rare bone tumour characterised histologically by the production of woven bone spicules, which are bordered by prominent osteoblasts.[] bone cysts mutiple osteoblastomas multiple well-marginated lytic lesions Differential diagnosis osteoid osteoma It is often difficult to differentiate an osteoblastoma from[] They present clinically with severe pain in the anterior knee or an obvious growth of soft tissue.[]

  • Osteoporosis

    The weaker spicules of trabecular bone break ("microcracks"), and are replaced by weaker bone.[] Interestingly, serum levels of Dkk-1 positively correlate with the extent of lytic bone lesions in patients with multiple myeloma. [36] Clinical trials of a monoclonal antibody[] Last year, she had a total knee replacement due to arthritis. She now walks with a cane because of chronic knee and ankle pain, and has experienced a loss of balance.[]

  • Bone Fibroma

    Multiple myeloma key facts : Most common primary malignant bone tumor Older adults Imaging: sharply circumscribed lytic lesions or diffuse demineralization.[] OSTEOBLASTOMA Definition: - Benign bone forming neoplasm producing woven bone spicules bordered by prominent osteoblasts (osteoid osteoma measuring more than 2.0 cm) Epdemiology[] […] and mild knee pain.[]

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