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73 Possible Causes for Bony Swelling, Knee Pain, Leukocytes Increased

  • Osteomyelitis

    The physical examination should focus on identifying common findings, such as erythema, soft tissue swelling or joint effusion, decreased joint range of motion, and bony tenderness[aafp.org] Ages range from 39 to 64 years, and reasons for amputation included infection, pain, and necrosis.[ncbi.nlm.nih.gov] […] bone turnover Radionuclide-labeled leukocyte scintigraphy : detects sites of infection or inflammation Sonography : assess soft tissue involvement Early stages of osteomyelitis[amboss.com]

  • Multiple Myeloma

    Trauma, new bony pain, or change in bony pain warrants repeat imaging with X-rays.[clinicaladvisor.com] CASE REPORT A 56-year-old man with multiple myeloma presented with chronic polyarticular pain and swelling.[ncbi.nlm.nih.gov] In addition, the levels of PS erythrocytes, platelets, leukocytes, and ECs incubated with IMiDs and dexamethasone were higher than with IMiDs alone.[ncbi.nlm.nih.gov]

  • Ewing's Sarcoma

    Patellar tumors occur infrequently and represent an uncommon etiology of anterior knee pain.[ncbi.nlm.nih.gov] A young patient presented with a progressive right knee pain and swelling that was worse on ambulation.[ncbi.nlm.nih.gov] Symptoms of Ewing sarcoma The main areas affected by Ewing sarcoma are the: legs (most often around the knee) pelvis arms ribs spine Symptoms include: bone pain – this may[nhs.uk]

  • Ewing Family of Tumors

    Heinrich Kovar b, Michael Paulussen c, R. Lor Randall d, Andreas Schuck e, Lisa A. Teot f and Herbert Juergensg g a Ste-Justine Hospital, University of Montreal, Montreal, Canada; b Children’s Cancer Research Institute, Vienna, Austria; c University Children’s Hospital Basel, Basel, Switzerland; d Huntsman Cancer[…][dx.doi.org]

  • Polyarticular Juvenile Idiopathic Arthritis

    This can cause swelling and the formation of bony spurs, called osteophytes.[nhs.uk] This is the case of RF-negative polyarticular juvenile idiopathic arthritis that was reported with six-week history of neck pain, torticollis and left knee effusion.[ncbi.nlm.nih.gov] DR5 (HLA-DR5) test puts patients at increased risk for developing uveitis.[eyewiki.aao.org]

  • Septic Arthritis

    Radiographs may be normal or show fluid or soft tissue swelling or increased joint space. Bony changes may not be apparent for 2-3 weeks.[pmmonline.org] Derek Isenberg and Dorian Jacobs, Knee Pain and Fever, Visual Journal of Emergency Medicine, 3, (15), (2016). Jacob Daynes, Matthew F.[doi.org] […] likelihood of septic arthritis (LR 7.7 positive; LR 0.42 negative) At least 90% leukocytes (LR 3.4 positive; LR 0.34 negative) Low WBC count common in immunosuppressed patients[arupconsult.com]

  • Osteomyelitis of the Tibia

    Clinically the patient presented with bony hard, non-tender swelling and the occlusal radiograph revealed pathognomic feature of "onion skin" appearance.[jisppd.com] Her knee pain too, did not abate.[ispub.com] Signs and symptoms include a marked increase in leukocytes; tenderness, swelling, and redness of the skin over the bone involved; and bacteremia.[medical-dictionary.thefreedictionary.com]

  • Sickle Cell Disease

    All the cases of HbSS presented with a joint swelling while it was seen in 53% of the HbAS.[doi.org] Other symptoms mentioned were pain in the hands (59%), pain in the limbs (58%), abdominal pain (56%) and pain in the knees (55%).[emro.who.int] Therefore, elevated PlGF levels may contribute to recruitment and activation of leukocytes.[ncbi.nlm.nih.gov]

  • Rheumatic Fever

    […] skin, often over bony areas Unusual jerky movements, most often of the face and hands.[urmc.rochester.edu] They may include: Fever Painful and tender joints, most often the ankles, knees, elbows or wrists Pain that moves from joint to joint Red, hot or swollen joints Small, painless[arthritis.org] No significant association with class-I human leukocyte antigens (HLAs) has been found, but an increase in class-II HLA antigens DR2 and DR4 has been found in black and white[emedicine.com]

  • Enthesitis-Related Arthritis

    Examination included physician's global assessment on 100 mm VAS, number of active joints as defined by presence of swelling (excluding bony swelling) or any two of limitation[ped-rheum.biomedcentral.com] The enthesitis is usually around the knee-caps, heels, and joint parts – usually backbone, hips, ankles and knees are painful and stiff.[enthesitis.org] Risk Factors Genetics Rare in siblings, but many studies have demonstrated increased frequencies of various human leukocyte antigen markers in JIA.[unboundmedicine.com]

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