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44 Possible Causes for Botulism, Descending Paralysis, Flaccid Paralysis

  • Botulism

    Abstract Botulism is the acute, flaccid paralysis caused by a neurotoxin produced by Clostridium botulinum.[] Clostridium botulinum is known to cause descending paralysis in infants throughout the world.[] […] clostridium botulinum Intoxication with Clostridium botulinum toxin Wound botulism (subtype) Infant botulism (subtype) Botulism Foodborne botulism (subtype) edit English[]

  • Wound Botulism

    The clinical picture of botulism is of descending, symmetric, flaccid paralysis.[] Wound botulism in 7 heroin 'skin poppers' produced ophthalmoplegia and descending paralysis.[] […] within the gut, in infant botulism.[]

  • Infantile Botulism

    paralysis.[] Note that, in many cases, descending paralysis may be absent.[] It is a decending, symmetric, flaccid paralysis, with cranial nerves palsies being the most common complication.[]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis in children.[] Differential diagnosis Acute myelopathy – back pain,sphincter disturbances Botulism –early loss of pupillaryactivity,descending paralysis Diphtheria –early oropharyngeal involvement[] Diagnostic testing for botulism has low sensitivity, so we urge pre-emptive treatment if it is clinically suspected.[]

  • Intestinal Botulism

    Botulism manifests as acute, descending, symmetric flaccid paralysis caused by neurotoxin-mediated blockade of presynaptic acetylcholine release [ 1 ].[] Intestinal colonization botulism, rare in adults, should be considered for patients with descending paralysis, especially those with a preceding alteration in small bowel[] , including infant botulism and shaker foal syndrome.[]

  • Tick Paralysis

    Tick paralysis is a rare disease characterized by acute, ascending, flaccid paralysis that is often confused with other acute neurologic disorders or diseases (e.g., Guillain-Barré[] […] that the acute ascending or rare descending type of paralysis originally described by Landry is simply a form of poliomyelitis, whereas others contend that Landry's paralysis[] […] of the eight most common tickborne diseases in the United States (1)--is an acute, ascending, flaccid motor paralysis that can be confused with Guillain-Barre syndrome, botulism[]

  • Neuromuscular Junction Disorder

    Differential diagnosis of flaccid paralysis Anterior horn disease Disorders of the NMJ  Polyemyelitis  Amyotrophic lateral sclerosis  Myasthenia gravis  Lambert-Eaton[] In its nontherapeutic form, the toxin is produced by bacteria and can cause a paralysis that starts with the muscles of the face and throat and descends over the rest of the[] Infantile Botulism Infantile botulism primarily occurs in infants 2 to 6 months of age.[]

  • Inhalational Botulism

    It is characterized by symmetric cranial nerve palsy, commonly followed by symmetric, descending, flaccid paralysis of involuntary muscles, which may result in respiratory[] Recognition of the clinical presentation characterized by bulbar palsies and descending paralysis in the absence of sensory or central nervous systems symptoms is key to making[] Food poisoning is the most common cause of botulism.[]

  • Food-Borne Botulism

    Botulism classically presents as acute symmetrical descending flaccid paralysis.[] Even small outbreaks of food-borne botulism can precipitate a national emergency and inundate public health and acute care provision.[] The toxin blocks acetylcholine receptors at neuromuscular junctions, which result in a descending type of flaccid paralysis of voluntary muscles.[]

  • Deliberate Exposure to Botulinum Toxin

    Situations suggesting release of botulinum toxin as a biological weapon: (1) Outbreak of acute flaccid paralysis with prominent bulbar palsies (diplopia, dysarthria, dysphonia[] Conclusions: An aerosolized or foodborne botulinum toxin weapon would cause acute symmetric, descending flaccid paralysis with prominent bulbar palsies such as diplopia, dysarthria[] Botulism can result in death due to respiratory failure; the proportion of patients with botulism who die is 3-5%.[]

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