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467 Possible Causes for Bradykinesia, Difficulty Walking, Motor Symptoms

  • Parkinson's Disease

    Olfactory deficit is considered the most common NMS in PD preceding the motor symptoms for years.[ncbi.nlm.nih.gov] Table 1 Parkinson’s disease symptoms Bradykinesia Bradykinesia refers to slowness of movement and is the most characteristic clinical feature of PD, although it may also be[web.archive.org] As these symptoms become more pronounced, patients may have difficulty walking, talking, or completing other simple tasks. PD usually affects people over the age of 60.[web.archive.org]

  • Parkinson's Disease Type 3

    The Parkinson’s community acknowledges that there are many important non-motor symptoms as well as motor symptoms.[parkinson.org] Parkinson's disease is a neurodegenerative disorder associated with muscle rigidity, tremor, and bradykinesia.[symptoma.com] Understanding Parkinson's Symptoms Some people with Parkinson’s will first notice a sense of weakness, difficulty walking, and stiff muscles.[webmd.com]

  • Parkinson-Dementia Syndrome

    Turning on the subthalamic nucleus electrodes improved motor symptoms but left cognitive performance almost unchanged.[ncbi.nlm.nih.gov] Postural instability and bradykinesia is noted on physical exam.[medbullets.com] .- Steele-Richardson-Olswenski syndrome- progressive supranuclear palsy-initial symptom in 2/3 of cases is loss of balance, difficulty walking -fast walking bumping into objects[defeatparkinsons.com]

  • Juvenile Paralysis Agitans of Hunt

    Several therapies are available to delay the onset of motor symptoms and to ameliorate motor symptoms.[medicinenet.com] 32 HP:0002067 9 parkinsonism 32 HP:0001300 Symptoms via clinical synopsis from OMIM: 57 Neuro: dysarthria gait disturbance tremor rigidity bradykinesia more Misc: onset in[malacards.org] Patients with PD have poor balance, a tendency to fall, and difficulty walking.[neupsykey.com]

  • Bradykinesia

    Usually, neurologists regularly monitor motor symptoms and motor fluctuations using the MDS-UPDRS part III clinical scale.[ncbi.nlm.nih.gov] In PD, facial bradykinesia is primarily mediated by basal ganglia dysfunction whereas in PSP, facial bradykinesia is a consequence of a widespread degeneration involving the[ncbi.nlm.nih.gov] walking Developmental regression Peripheral axonal neuropathy Distal amyotrophy Tetraparesis Spastic paraparesis Abnormality of thalamus morphology Obsessive-compulsive behavior[mendelian.co]

  • Secondary Parkinsonism

    BACKGROUND: Non-Motor Symptoms (NMS) are frequent in patients with Idiopathic Parkinson's Disease (IPD).[clinicaltrials.gov] Gradually, bradykinesia diminished slightly and vigilance increased little.[ncbi.nlm.nih.gov] These patients complain of difficulty with walking, and upon examination, have an abnormal gait with small steps, shuffling, freezing and falls.[pdprogram.org]

  • Huntington's Disease

    In addition, multiple regressions were performed to investigate the impact of family history on the age at onset of depression and motor symptoms.[ncbi.nlm.nih.gov] However, GPi-DBS-induced bradykinesia may emerge as one main limitation of GPi-DBS in HD.[ncbi.nlm.nih.gov] He had depression, poor cognitive function, choreiform movements, difficulty pronouncing words, and difficulty walking.[ncbi.nlm.nih.gov]

  • Classic Progressive Supranuclear Palsy Syndrome

    Motor symptoms appear later in the course of the disease.[orpha.net] PSP-CBS is characterized by progressive asymmetric dyspraxia, limb rigidity, bradykinesia, and progressive postural instability.[orpha.net] […] with eye movement, slow movements, cognitive dysfunction, and difficulty walking that can result in falls.[alzheimer-europe.org]

  • Progressive Supranuclear Palsy

    All these non-motor symptoms in PSP mimicked those of multiple system atrophy.[ncbi.nlm.nih.gov] UPDRS total motor scores and subscores for bradykinesia and axial motor deficits did not correlate with R2* values of the five brain regions.[ncbi.nlm.nih.gov] […] of the face Deeply lined face Eye and vision problems such as different sized pupils, difficulty moving the eyes ( supranuclear ophthalmoplegia ), lack of control over the[nlm.nih.gov]

  • Prion Disease

    The motor symptoms of vCJD (stumbling, falls and difficulty walking) also tend to appear earlier in vCJD than in classic CJD.[memory.ucsf.edu] The first patient experienced progressive bradykinesia, ataxia, and slurred speech developing over a two-week period.[web.archive.org] However, in that family, there was a longer delay from the onset of psychiatric symptoms to the development of motor symptoms than in our proband. 15 Boesenberg et al 16 found[jamanetwork.com]

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