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385 Possible Causes for Brisk Reflexes, Progressive Peripheral Neuropathy

  • Spinal Muscular Atrophy with Respiratory Distress Type 1

    Patients with hypotonic cerebral palsy may often have brisk deep tendon reflexes ( 2 ).[tidsskriftet.no] This finding suggests the rapid progression of peripheral axonal neuropathy in SMARD1 that leads to its characteristic clinical course of respiratory failure and paralysis[ncbi.nlm.nih.gov] […] symmetrical muscular weakness (distal lower limbs mainly involved), muscle atrophy, and peripheral sensory neuropathy.[ncbi.nlm.nih.gov]

  • Paraparesis

    Hereditary spastic paraparesis : Spastic paraparesis, brisk reflexes, upgoing plantars. Absence of sensory signs.[ptpaces.wordpress.com] Entries on cerebellar diseases, peripheral neuropathies, various dementias, diagnostic tests (both clinical and laboratory), forms of cerebral edema, dissociative signs and[books.google.com] […] limbs (though no cogwheeling), and pathologically brisk reflexes.[academic.oup.com]

  • Gangliosidosis

    Reflexes were diffusely brisk with bilateral extensor plantar responses.[jamanetwork.com] One juvenile patient developed peripheral neuropathy, and others showed progression of already established neuropathy, which was judged to be part of the natural progression[ncbi.nlm.nih.gov] Thus the disease can clinically present accordingly with upper motor neuron lesions like spasticity and brisk deep tendon reflexes despite the presence of cherry red spot[casereports.in]

  • Triple A Syndrome

    The first case had upper muscle weakness and ataxia and brisk reflexes.[jpediatricsreview.com] It is characterized by a classical clinical triad: alacrima, achalasia and adrenal insufficiency, the canonic symptoms that are associated with progressive peripheral neuropathy[ncbi.nlm.nih.gov] […] symptoms (including cerebellar ataxia, peripheral neuropathy and mild dementia) suggest that the central nervous system may be involved in the disease as well.[ncbi.nlm.nih.gov]

  • Demyelinating Disease

    Physical examination showed a bilateral pale disc with normal visual acuity, quadriparesis with brisk reflexes and upgoing plantar responses and sensory loss at T12-L1.[jmedicalcasereports.com] Anti-MAG peripheral neuropathy. Progressive inflammatory neuropathy.[epainassist.com] neuropathy Charcot–Marie–Tooth disease and its counterpart Hereditary neuropathy with liability to pressure palsy Copper deficiency associated conditions ( peripheral neuropathy[en.wikipedia.org]

  • Worster-Drought Syndrome

    He has profuse dribbling, reduced oral movements and a brisk jaw jerk. He has generally increased tone with brisk reflexes and ankle clonus.[academic.oup.com] Entries on cerebellar diseases, peripheral neuropathies, various dementias, diagnostic tests (both clinical and laboratory), forms of cerebral edema, dissociative signs and[books.google.com] In most cases (40/45, 89%), this was brisk reflexes, with 20/40 (50%) having increased tone, 15/27 having extensor plantars and 12/39 (31%) having clonus.[academic.oup.com]

  • Metachromatic Leukodystrophy

    Contrary to the infantile form, deep tendon reflexes are usually brisk. There is also a milder adult form .[merckmanuals.com] Our patient has a progressive peripheral neuropathy but has apparently intact CNS function at her present age of 57 years.[ncbi.nlm.nih.gov] Signs of white matter involvement (spasticity, brisk tendon reflexes, extensor plantar responses) are prominent.[neuropathology-web.org]

  • Monomelic Amyotrophy

    Regional reflexes were variably absent. Two patients (18%) had brisk reflexes of lower limbs with flexor plantars.[annalsofian.org] Entries on cerebellar diseases, peripheral neuropathies, various dementias, diagnostic tests (both clinical and laboratory), forms of cerebral edema, dissociative signs and[books.google.com] Brisk reflexes will occur in a wasted limb. There is an absence of major sensory symptoms and pain. There is a relentless progression of symptoms and signs.[patient.info]

  • Nitrous Oxide

    Physical examination was notable for pathologically brisk reflexes in all extremities, generalized flexion contracture of the fingers, decreased sensation in a stocking and[ncbi.nlm.nih.gov] […] of the peripheral nerves and cervicothoracic spinal cord (posterior and anterolateral columns) giving a peripheral neuropathy and very frequently subacute combined degeneration[ncbi.nlm.nih.gov] The neurological condition triggered by anaesthesia with nitrous oxide involves the cyanocobalamine pathway and is characterised by progressive demyelination and axonal lesions[ncbi.nlm.nih.gov]

  • Progressive Muscular Atrophy

    The occurrence of upper motor neurone symptoms such as brisk reflexes, spasticity, or a Babinski sign would indicate a progression to ALS; the correct diagnosis is also occasionally[en.wikipedia.org] Entries on cerebellar diseases, peripheral neuropathies, various dementias, diagnostic tests (both clinical and laboratory), forms of cerebral edema, dissociative signs and[books.google.com] These patients tend to have more rapidly progressive weakness than is typical for the immune-mediated motor neuropathies.[neuromuscular.wustl.edu]

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