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260 Possible Causes for Brisk Reflexes, Progressive Peripheral Neuropathy

  • Metachromatic Leukodystrophy

    Contrary to the infantile form, deep tendon reflexes are usually brisk. There is also a milder adult form .[merckmanuals.com] CONCLUSIONS: Our patient has a progressive peripheral neuropathy but has apparently intact CNS function at her present age of 57 years.[ncbi.nlm.nih.gov] Signs of white matter involvement (spasticity, brisk tendon reflexes, extensor plantar responses) are prominent.[neuropathology-web.org]

  • Amyotrophic Lateral Sclerosis 17

    neuropathy ALS has normal sensory studies on EMG/NCS Treatment Nonoperative currently no cure or effective treatment goals of treatment provide supportive care prevent progression[orthobullets.com] […] tendon reflexes Also see: CMT 4J SLC11A2 37 Genetics Chromosome locus: 12q13.12 Feature: rs407135 with C allele SLC11A2 protein Divalent metal transporter (DMT1) Carries[neuromuscular.wustl.edu] In particular, diseases such as ALS, multifocal motor neuropathy (a form of peripheral neuropathy ) and spinal muscular atrophy need to first be ruled out first before a conclusive[verywell.com]

  • Lethal Ataxia with Deafness and Optic Atrophy

    Many of the disorders are associated with upper motor neuron signs such as brisk deep tendon reflexes, spasticity, and extensor plantar responses.[what-when-how.com] Plantar responses remain normal while peripheral neuropathy and seizures are not consistent features. MRI imaging of the brain is normal.[disorders.eyes.arizona.edu] […] with peripheral or optic neuropathy, prelingual progressive sensorineural hearing loss, and central nervous system impairment.[ncbi.nlm.nih.gov]

  • Congenital Neuropathy with Arthrogryposis Multiplex

    Nervous system problems include loss of vigor; lethargy; sluggish, brisk, or absent deep tendon reflexes; and sensory deficits.[emedicine.medscape.com] Congenital non-progressive peripheral neuropathy with arthrogryposis multiplex G. M. Yuill , P. G.[jnnp.bmj.com] Neurologic: Abnormal reflexes: absent, diminished, or brisk. Hypotonia may or may not be present. Sensation generally intact.[now.aapmr.org]

  • Autosomal Recessive Spastic Paraplegia Type 18

    Diagnosis Genetic Instrumental testing Tests Examination leg muscles Brain and spine MRI Family feel stiff Rule out other history causes brisk reflexes any History relatives[slideshare.net] CMT2X patients manifest a slowly progressive, peripheral neuropathy affecting the lower limbs and resulting in gait difficulties and distal sensory impairment.[genecards.org] Investigations also found the patient to have brisk tendon reflexes and clonus on elicitation. His 19-year-old sister showed milder symptoms.[cags.org.ae]

  • Autosomal Recessive Spastic Paraplegia Type 5A

    Diagnosis Genetic Instrumental testing Tests Examination leg muscles Brain and spine MRI Family feel stiff Rule out other history causes brisk reflexes any History relatives[slideshare.net] CMT2X patients manifest a slowly progressive, peripheral neuropathy affecting the lower limbs and resulting in gait difficulties and distal sensory impairment.[genecards.org] This also results in brisk reflexes, extensor plantar reflexes, muscle weakness, and variable bladder disturbances.[en.wikipedia.org]

  • Autosomal Recessive Spastic Paraplegia Type 26

    Diagnosis Genetic Instrumental testing Tests Examination leg muscles Brain and spine MRI Family feel stiff Rule out other history causes brisk reflexes any History relatives[slideshare.net] Additional features include intellectual disability, peripheral neuropathy, dysarthria, cerebellar signs, extrapyramidal signs, and cortical atrophy.[malacards.org] HSP can be associated with brisk reflexes, extensor plantar reflexes, and urinary urgency (2).[dnatesting.uchicago.edu]

  • Paraparesis

    Hereditary spastic paraparesis : Spastic paraparesis, brisk reflexes, upgoing plantars. Absence of sensory signs.[ptpaces.wordpress.com] Entries on cerebellar diseases, peripheral neuropathies, various dementias, diagnostic tests (both clinical and laboratory), forms of cerebral edema, dissociative signs and[books.google.com] Several family members from two generations were studied RESULTS: Neurological examination revealed weakness and spasticity in the lower limbs with brisk reflexes in all four[n.neurology.org]

  • Autosomal Recessive Spastic Paraplegia Type 21

    Diagnosis Genetic Instrumental testing Tests Examination leg muscles Brain and spine MRI Family feel stiff Rule out other history causes brisk reflexes any History relatives[slideshare.net] Abstract Hereditary ataxia is a heterogeneous disorder characterized by progressive ataxia combined with/without peripheral neuropathy, extrapyramidal symptoms, pyramidal[e-jmd.org] HSP can be associated with brisk reflexes, extensor plantar reflexes, and urinary urgency (2).[dnatesting.uchicago.edu]

  • Autosomal Dominant Spastic Paraplegia Type 10

    Diagnosis Genetic Instrumental testing Tests Examination leg muscles Brain and spine MRI Family feel stiff Rule out other history causes brisk reflexes any History relatives[slideshare.net] neuropathy, cognitive impairment, epilepsy, amyotrophy, retinopathy, deafness, icthyosis and extrapyramidal involvement, in addition to spastic paraparesis.[medicbind.com] HSP can be associated with brisk reflexes, extensor plantar reflexes, and urinary urgency (2).[dnatesting.uchicago.edu]

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