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184 Possible Causes for Broad and Flat Nose, Epicanthal Folds

  • Pallister-Killian Syndrome

    folds large ears with lobes that are thick and protrude outward.[en.wikibooks.org] […] ridges, upslanting palpebral fissures, hypertelorism, flat and broad nasal bridge, short nose with upturned nares, large mouth with downturned corners and prominent upper[orpha.net] Patients also exhibit a distinctive facial structure, characterized by high foreheads, sparse hair on the temple, a wide space between the eyes, epicanthal folds and a flat[popflock.com]

  • 22q11.2 Duplication Syndrome

    folds) and downslanting eyes.[thinkgenetic.com] folds.[doi.org] […] of skin over the inside corners of the eyes ( epicanthal folds ), low set ears, a small lower jaw ( micrognathia ), and a rounded face.[portal.bsc.gwu.edu]

  • Pallister W Syndrome

    folds large ears with lobes that are thick and protrude outward.[en.wikibooks.org] flat nose, widely spaced slanted eyes, and/or downslanting eyelid folds (palpebral fissures).[hekimce.com] Patients also exhibit a distinctive facial structure, characterized by high foreheads, sparse hair on the temple, a wide space between the eyes, epicanthal folds and a flat[en.wikipedia.org]

  • Down Syndrome

    folds, flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21 — called also Down, Down's, trisomy[merriam-webster.com] They tend to have a small head and a face that is broad and flat with slanting eyes and a short nose.[merckmanuals.com] Abnormalities are variable from individual to individual and may include mental retardation, retarded growth, flat hypoplastic face with short nose, prominent epicanthic skin[icd9data.com]

  • Noonan Syndrome

    ., epicanthal folds, ptosis, ocular hypertelorism), and micrognathia. Individuals with Noonan syndrome often may have either pectus excavatum or pectus carinatum.[symptoma.com] The nasal root is flat, the nasal tip is broad and the ears are low-set and posteriorly rotated.[patient.info] External features were hypertelorism (74%), downward sloping palpebral apertures (38%), epicanthic folds (39%) and ptosis (48%).[nature.com]

  • Williams Syndrome

    folds ) Partially missing teeth, defective tooth enamel, or small, widely spaced teeth Exams and Tests Signs include: Blood vessel narrowing including supravalvular aortic[web.archive.org] […] forehead, periorbital fullness, flat malar, full cheeks, low nasal root, short upturned nose, long philtrum, wide mouth, thick lips, small jaw, dental anomalies, hoarse voice[scielo.br] folds (vertical skin folds that cover the inner corners of the eyes Feeding difficulties in infancy, often leading to poor growth Shorter than average height Low body tone[my.clevelandclinic.org]

  • Dubowitz Syndrome

    Ocular problems occur in about 20%: strabismus, blefarophimosis, ptosis, telecanthus and epicanthal folds being the most frequent ones.[ncbi.nlm.nih.gov] broad Flat nasal bridge Lateral telecanthus Drooping upper eyelid Eyes are wide-set Blepharophimosis Prominent ears Epicanthal folds Dysplastic ears that is mild Lower jaw[syndrome.org] Dubowitz syndrome is an autosomal recessive condition characterized by pre- and postnatal growth retardation, eczema, telecanthus, epicanthal folds, blepharophimosis, ptosis[ncbi.nlm.nih.gov]

  • Blepharophimosis

    folds.[ncbi.nlm.nih.gov] We report four children with unusual facial features including severe blepharophimosis, ptosis, and a distinctive nose with a broad flat tip and a depressed bridge.[ncbi.nlm.nih.gov] The patient has bilateral ptosis with reduced lid size.There are inverted epicanthal folds, telecanthus. The nasal bridge is flat and there is hypoplastic orbital rim.[mrcophth.com]

  • Acrodysostosis

    […] of skin on either side of the nose that may cover the eyes' inner corners (epicanthal folds).[healthetreatment.com] Other common abnormalities include short head (as measured front to back), small broad upturned nose with flat nasal bridge, protruding jaw, increased bone age, intrauterine[en.wikipedia.org] nose with flat bridge Distinct features of the face (short nose, open mouth, jaw that sticks out) Unusual head Wide-spaced eyes, sometimes with extra skin fold at corner[nlm.nih.gov]

  • Cri Du Chat Syndrome

    Among the consequent abnormalities are low birth weight, a striking catlike cry in infancy, mental retardation, epicanthal folds, hypertelorism and dental malocclusions.[ncbi.nlm.nih.gov] Case 2, 5-year-old boy, exhibited physical and mental retardation, microcephaly with flat occiput, antimongoloid slant, spicanthus, broad base of the nose, simian line, and[petit.lib.yamaguchi-u.ac.jp] The mother had hypertelorism, epicanthal folds, and mild mental deficiency while the son had additional anomalies that have been observed in patients with cri-du-chat syndrome[ncbi.nlm.nih.gov]

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