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405 Possible Causes for Broad and Flat Nose, Open Metopic Suture, Overfolded Superior Helix

  • Pallister W Syndrome

    superior helix and small anthelix, sometimes cupped, with preauricular tags (fig 1 ).[jmg.bmj.com] flat nose, widely spaced slanted eyes, and/or downslanting eyelid folds (palpebral fissures).[hekimce.com] The symptoms usually include microbrachycephaly, synostosis involving chiefly the cranial suture, open sagittal and lamdoid sutures, patent metopic suture, hypertelorism,[whonamedit.com]

  • FGFR2-Related Bent Bone Dysplasia

    NIH Rare Diseases : 53 Bent bone dysplasia syndromeis an often lethal skeletal disorder characterized by poor mineralization of the skull (calvarium), craniosynostosis, underdeveloped (hypoplastic) pubic bone (pubis) and clavicles, osteopenia, and bent long bones. Unusual facial features include low-set ears, widely[…][malacards.org]

    Missing: Broad and Flat Nose
  • Kaufman Oculocerebrofacial Syndrome

    Symptoms INHERITANCE: Autosomal dominant HEAD AND NECK: [Head]; Open metopic suture; [Face]; Midface hypoplasia; Micrognathia; [Ears]; Low-set ears; Overfolded superior helix[findzebra.com] Nasal malformations Nasal anomalies were common with 24 having a broad nose or nasal bridge (20.5%, table 7), 13 with a depressed or flat nasal bridge (11.1%), and 18 with[jmg.bmj.com] broad eyebrows Long face – Thin skin Craniofacial – Sparse thin scalp hair Skin and hair – Microcephaly/OFC Short stature Growth M Parental consanguinity Sex Hispanic Origin[docksci.com]

  • Trigonocephaly

    Craniofacial anomalies, which can be seen with other anticonvulsant exposures, including midface hypoplasia, short nose with a broad and / or flat bridge, epicanthal folds[doi.org] Welcker's (1, 4) anatomical diagram shows the metopic suture of his patient open.[doi.org] Surgical treatment by opening of the prematurely fused metopic suture and expansion of the anterior cranial base by creating "neosutures" was used to treat three children[ncbi.nlm.nih.gov]

    Missing: Overfolded Superior Helix
  • Cloverleaf Skull

    Abnormally high and broad forehead Ocular proptosis – severe protrusion of the eyes Midface hypoplasia – flat middle portion of the face “Beak-shaped” nose Downwardly displaced[drugsdetails.com] Cranio-facial CT scan with three-dimensional reconstruction: wide open metopic suture with absence of coronal sutures (a, b).[em-consulte.com] Physical examination showed a closed sagittal suture, a laterally fused coronal suture, and open temporal, metopic, and lambdoid sutures ( Figures 1-3 ).[consultant360.com]

    Missing: Overfolded Superior Helix
  • Kleiner Holmes Syndrome

    superior helix; Deficient auricle; Hypertelorism; Megalophthalmos; Gingival hyperplasia; Prenatal teeth; Bell-shaped thorax; Hypoplastic clavicles; Decreased mineralization[panelapp.genomicsengland.co.uk] metopic suture; Midface hypoplasia; Micrognathia; Low-set ears; Overfolded superior helix; Deficient auricle; Hypertelorism; Megalophthalmos; Gingival hyperplasia; Prenatal[panelapp.genomicsengland.co.uk] […] mental retardation [; ; ]; #613659:Gastric cancer, somatic [; ; ]; #614592:Bent bone dysplasia syndrome [Open metopic suture; Midface hypoplasia; Micrognathia; Low-set ears; Overfolded[panelapp.genomicsengland.co.uk]

    Missing: Broad and Flat Nose
  • Branchio-Oculo-Facial Syndrome

    […] with hypoplastic superior helix, posterior and preauricular pit, supraauricular sinuses, conductive hearing loss secondary to fusion of the middle ear ossicles), the eyes[accessanesthesiology.mhmedical.com] […] fissures with lacrimal duct obstruction, broad nose with a broad nasal root, and denudation of the cervical skin (Fig. 3).[documents.tips] […] divided nasal tip, depressed nasal bridge, short nasal septum, cleft lip and palate, lip pits, dental abnormalities), the ears (microtic, low-set and/or posteriorly rotated, overfolded[accessanesthesiology.mhmedical.com]

    Missing: Open Metopic Suture
  • Familial Scaphocephaly Syndrome

    Common differences of the facial region includes epicanthal folds ("oriental" looking eyelids), broad cheeks, low set, uneven and malformed ears, flat nasal bridge, small[craniokids.co.za] Causes The metopic suture is usually open at birth and fusion normally occurs in the first 12 months of life.[skullbaseinstitute.com] Only one suture - the metopic - normally closes during the first few years of life, and the others remain open into adulthood.[craniofacial.vcu.edu]

    Missing: Overfolded Superior Helix
  • Craniosynostosis

    Or it may be very flat and broad in front or back or on the sides. The baby may have a misshapen nose or jaw.[myhealth.alberta.ca] The cranial sutures in neonates appear wide open and fuse with age from back to front and lateral to medial with the exception of the metopic suture, which fuses from front[ncbi.nlm.nih.gov] All sutures remain open until adulthood, except for the metopic suture which usually closes between 6 and 12 months of age.[childrens.com]

    Missing: Overfolded Superior Helix
  • Coffin-Lowry Syndrome

    superior helix [ Graham et al 1998 ].[ncbi.nlm.nih.gov] […] supraorbital ridges with bushy brows, downwardly slanted palpebral fissures, hypertelorism, blepharoptosis, large and prominent ears, large nose with broad base and elongated[accessanesthesiology.mhmedical.com] Broad-based nose with a thick septum. Pouting everted lower lip; smooth tongue. Low-set ears. Hypodontia (Figure 2). Thick and loose skin, velvety surface.[jped.com.br]

    Missing: Open Metopic Suture