Possible Causes for broad based gait Duchenne Muscular Dystrophy Duchenne muscular dystrophy (DMD) is the most common neuromuscular disease affecting boys. Advances in their care can delay the progression of DMD-related disability and prolong survival. The administration of glucocorticoids is among these advances. Glucocorticoid therapy, however, is associated with a myriad of[…] [ncbi.nlm.nih.gov] Subacute Combined Degeneration of Spinal Cord His gait was broad based with spinal ataxia. Decreased graphaesthesia was found on the lower limbs, the lower part of the trunk and on the upper limbs. [neuroanatomy.wisc.edu] Diabetic Pseudotabes In addition to the broad-based, stamping gait, which becomes worse when patients try to walk in the dark, abnormal findings included diminished vision owing to optic atrophy [std-aid.com] Ataxia of gait is evident, and results of heel-to-sin and finger-to-nose testing are abnormal. [std-aid.com] Friedreich Ataxia The unsteadiness further progresses to a broad-based,… Read More mitochondrial disorders In metabolic disease: Mitochondrial disorders …iron homeostasis is present in Friedreich [britannica.com] With progression, gait becomes broad-based, with frequent losses of balance requiring intermittent and then constant support. [doi.org] Gait ataxia develops early and gait is characteristically unsteady, but not overtly broad-based. [academic.oup.com] Tabes Dorsalis The patient's ataxia was evident as she walked with a broad-based gait. [lksom.temple.edu] Argyll-Robertson pupils Impaired vibratory and proprioception sense Broad base and sensory ataxic gait Positive Romberg's test Tabes dorsalis Positive VDRL Rapid plasma reagent [wikidoc.org] [1][2][3][4] Diseases History and symptoms Physical examination Laboratory findings Other findings Lightning pains Impaired sensation Progressive sensory ataxia Unsteady gait [wikidoc.org] Acute Cerebellar Ataxia A 29-year-old man developed acute cerebellar ataxia following Epstein-Barr virus infection. Serum IgG and IgM antibodies reacted with both nuclear and cytoplasmic elements of neurons. Western blot revealed IgG binding to the 34- and 29-kd bands and IgM binding to the 44-, 37-, and 29-kd bands. The IgM reactivity[…] [ncbi.nlm.nih.gov] Hereditary Areflexic Dystasia C. Haubrich T. Krings J. Senderek S. Züchner J. Schröder J. Noth R. Töpper Diagnostic Neuroradiology Abstract. Hypertrophic radiculopathy is a rare feature of neuropathies. Single cases of enlarged nerve roots have been described in hereditary motor sensory neuropathies (HMSN) and chronic inflammatory[…] [doi.org] Ataxic Cerebral Palsy Patients with ataxic cerebral palsy will usually have a broad-based gait, i.e. they walk with their feet unusually far apart. [medhelp.org] Showing of 9 Percent of people who have these symptoms is not available through HPO Autosomal recessive inheritance 0000007 Broad-based gait Wide based walk 0002136 Cerebellar [rarediseases.info.nih.gov] Ataxia Telangiectasia A 9-year-old girl born to healthy parents showed manifestations suggestive of ataxia telangiectasia (AT), such as short stature, sudden short bouts of horizontal and rotary nystagmus, a weak and dysarthric voice, rolling gait, unstable posture, and atactic movements. She did not show several cardinal features[…] [ncbi.nlm.nih.gov] Ochronosis with Alkaptonuria Abstract A 59-year-old woman with previously documented alkaptonuria was examined for extensive ochronosis of recent onset. The cause of the extensive skin pigmentations were thought to be secondary to decreased renal clearance of homogentisic acid because of a decline in the patient's renal function. If[…] [ncbi.nlm.nih.gov] Dysequilibrium Syndrome […] is not available through HPO Abnormality of metabolism/homeostasis Laboratory abnormality Metabolism abnormality [ more ] 0001939 Autosomal recessive inheritance 0000007 Broad-based [rarediseases.info.nih.gov] gait Wide based walk 0002136 Cerebellar atrophy Degeneration of cerebellum 0001272 Cerebellar hypoplasia Small cerebellum Underdeveloped cerebellum [ more ] 0001321 Congenital [rarediseases.info.nih.gov] Wiedemann-Steiner Syndrome […] behavior Aggression Aggressive behaviour Aggressiveness [ more ] 0000718 Autosomal dominant inheritance 0000006 Blepharophimosis Narrow opening between the eyelids 0000581 Broad-based [rarediseases.info.nih.gov] gait Wide based walk 0002136 Clinodactyly of the 5th finger Permanent curving of the pinkie finger 0004209 Delayed speech and language development Deficiency of speech development [rarediseases.info.nih.gov] Polyneuropathy Systemic Features: Gait disturbances have their onset in the first or second decades of life. The gait may be broad-based. [disorders.eyes.arizona.edu] Limb-Girdle Muscular Dystrophy Type 2E Showing of 23 30%-79% of people have these symptoms Broad-based gait Wide based walk 0002136 Calf muscle hypertrophy Increased size of calf muscles 0008981 Delayed speech [rarediseases.info.nih.gov] Diabetic Autonomic Neuropathy Gait and station: The patient walks with a broad-based antialgic gait leaning on the outer edge of the foot (Figure 1). [ibimapublishing.com] Astrocytoma The authors described the case of a 69 year-old patient presenting with a broad-base gait, bilateral pain and dysesthesia of inferior limbs with a diagnosis of an intra-axial [ncbi.nlm.nih.gov] Normal Pressure Hydrocephalus Her neurological examination was normal except for a broad-based shuffling gait. [aansneurosurgeon.org] In mild cases, patients may display a broad‐based gait but in more severe cases there is a reduction in stride length [ 30 ]. [intechopen.com] The gait disturbance features a broad-based, small-step, magnetic gait with the feet turning outwards, resembling that of patients with Parkinsonʼs disease 6. [ncbi.nlm.nih.gov] Classic Progressive Supranuclear Palsy Syndrome based gait of cerebellar ataxia. [pmj.bmj.com] The gait of a PSP patient is mildly unsteady and broad based. [alzheimer-europe.org] […] reeling or staggering quality, due to the stiff posture of the trunk and neck with irregular large steps forwards, which allow a distinction to be made from the veering broad [pmj.bmj.com] Bickerstaff Brainstem Encephalitis On exam, he had right arm and leg ataxia, symmetrically hyperactive reflexes, broad-based ataxic gait, and nausea with vomiting. [neurology.org] based ataxic gait. [hindawi.com] He recently came to our hospital with a 2 week history of worsening gait and right-handed clumsiness. [neurology.org] Klinefelter Syndrome He sat at 18 months, crawled at 22 months and a broad-based flat-footed gait was observed at 3 years of age. [scielo.br] Cervical Myelopathy The final model included age (relative risk [RR] 0.924, p 0.0001), smoking status (RR 0.837, p 0.0043), broad-based unstable gait (RR 0.869, p 0.0036), and duration of symptoms [ncbi.nlm.nih.gov] RESULTS: Numb hands and Hoffmann sign were associated with greater MSCC ( P .05); broad-based, unstable gait, impairment of gait, and Hoffmann sign were associated with greater [ncbi.nlm.nih.gov] Discussion: - characterized by weakness (upper lower extremity); - ataxic broad based suffling gait, sensory changes; - rarely urinary retention; - anatomy of compression [wheelessonline.com] Muscular Dystrophy-Dystroglycanopathy Type C4 Showing of 23 30%-79% of people have these symptoms Broad-based gait Wide based walk 0002136 Calf muscle hypertrophy Increased size of calf muscles 0008981 Delayed speech [rarediseases.info.nih.gov] Uncinate Seizure Lack of balance and broad based gait. Inco-ordination, hypotonia and nystagmus may occur. Mixed type of any of the above features. 39. [slideshare.net] Myelopathy […] grasping and holding objects, diffuse numbness in the hands, and increasing difficulty with balance and ambulation. 2, 10, 16 Physical examination may reveal unsteadiness, broad-based [doi.org] Discussion: - characterized by weakness (upper lower extremity); - ataxic broad based suffling gait, sensory changes; - rarely urinary retention; - anatomy of compression [wheelessonline.com] based, unstable gait And, MRI evidence of cervical spondylotic myelopathy Scheduled for an elective surgery for cervical spondylotic myelopathy Preoperative mJOA score 8 [clinicaltrials.gov] Pallidopyramidal Syndrome Uncommon Symptoms - Between 30% and 50% cases Global developmental delay Fatigue Cerebellar atrophy Dysarthria Hyperreflexia Cognitive impairment Spasticity Distal amyotrophy Broad-based [mendelian.co] gait Dystonia Rod-cone dystrophy Rigidity Agitation Dyskinesia Progressive neurologic deterioration Gait disturbance Coma Muscle weakness Optic atrophy Neonatal hypotonia [mendelian.co] Cerebral Neoplasm broad-based gait) Most tumors arise within the cerebellar vermis (midline) Invasion or compression of the 4th ventricle non-communicating hydrocephalus features of raised [amboss.com] Hydrocephalus Gait disturbances can make the way to the toilet more difficult, leading to further incontinence related issues Dementia Frequent falls, broad-based gait with short steps [amboss.com] The typical gait abnormality in NPH is a broad-based, slow, short-stepped, "stuck to the floor", or "magnetic" movement. [en.wikipedia.org] […] ventricles to the subarachnoidal space Normal pressure hydrocephalus (NPH) CSF absorption Classic triad Wet: urinary incontinence Wacky: dementia Wobbly: frequent falls, broad-based [amboss.com] Spinocerebellar Ataxia Type 19 Truncal ataxia Instability or lack of coordination of central trunk muscles 0002078 Urinary incontinence Loss of bladder control 0000020 5%-29% of people have these symptoms Broad-based [rarediseases.info.nih.gov] gait Wide based walk 0002136 Cogwheel rigidity 0002396 Diplopia Double vision 0000651 Dysarthria Difficulty articulating speech 0001260 Impaired smooth pursuit 0007772 Nystagmus [rarediseases.info.nih.gov] Radiculomyelopathy […] decompression without fusion 4 C5/6 anterior discectomy and fusion ML 3 Select Answer to see Preferred Response PREFERRED RESPONSE 5 (OBQ07.180) A 63-year-old female presents with a broad-based [orthobullets.com] […] shuffling gait, loss of manual dexterity, and exaggerated deep tendon reflexes in the lower extremities. [orthobullets.com] Open-Angle Glaucoma On examination at age 9 years, she had a broad-based, ataxic gait with dystonic posturing of the lower limbs. [jamanetwork.com] Patient IV:6 had a normal birth and early development, but by the age of 5 to 6 years, her gait was unsteady with frequent falls. [jamanetwork.com]
