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227 Possible Causes for Broad-Based Gait, Dysarthria

  • Cerebellar Ataxia

    Patient 2 initially presented with an increased startle response and myoclonic jerks, and subsequently developed severe limb and gait ataxia, dysarthria, oculomotor disturbances[ncbi.nlm.nih.gov] There is a broad-based gait, scanning dysarthria, explosive speech, intention tremor, dysdiadochokinesia, dysmetria and abnormalities of eye movements.[patient.info] Cerebellar ataxia associated with glutamic acid decarboxylase autoantibodies (GAD-ab) is a rare and usually slow progressive disease with moderate to severe gait and limb ataxia, dysarthria[ncbi.nlm.nih.gov]

  • Friedreich Ataxia

    Here we aimed to compare dysarthria profiles of patients with (SCA3 and SCA6 vs.[ncbi.nlm.nih.gov] Friedreich Ataxia (FRDA) is the most common hereditary ataxia, with dysarthria as one of its key clinical signs.[ncbi.nlm.nih.gov] The classic phenotype of Friedreich ataxia is characterized by dysarthria, progressive limb and trunk ataxia, loss of reflexes, and gait disturbance with the onset of disease[ncbi.nlm.nih.gov]

  • Niemann-Pick Disease Type C

    With the exception of developmental delay/cognitive impairment, these results persisted after 48-96 months in 41 - 55% of the patients (dystonia: 55%, dysarthria: 50%, gait[ncbi.nlm.nih.gov] Neurological examination revealed a broad-based ataxic gait, limb dysmetria, downward vertical gaze palsy, brisk lower limb reflexes and ankle clonus, while neuropsychological[ncbi.nlm.nih.gov] Major clinical features included cerebellar ataxia (76%), vertical supranuclear ophthalmoplegia (VSO, 75%), dysarthria, (63%), cognitive troubles (61%), movement disorders[ncbi.nlm.nih.gov]

  • Cerebellar Disease

    These dysprosodic aspects of ataxic dysarthria are discussed in relation to cerebellar function in motor control.[ncbi.nlm.nih.gov] No- differentiates a cerebellar broad based gait from a sensory broad based gait. How is the speech in cerebellar syndrome described?[brainscape.com] OPCA Toxic/metabolic diseases Hypothyroidism & normal pressure hydrocephalus Ataxic Dysarthria: Neuromotor Deficits Hypotonia and reduced resistance to passive movement Broad-based[ucs.louisiana.edu]

  • Ataxia Telangiectasia

    AT manifests as ataxia, apraxia, telangiectasia, and dysarthria. Common ophthalmologic findings in AT include fine conjunctival telangiectasia.[ncbi.nlm.nih.gov] Prior to cancer therapy, all had non-progressive atypical neurological abnormalities, with onset by age 30 months, including dysarthria, dyskinesia, hypotonia and/or dystonia[ncbi.nlm.nih.gov] […] performed on an Iranian 5-year-old boy presented with truncal and limb ataxia, telangiectasia of the eye, Hodgkin lymphoma, hyper pigmentation, total alopecia, hepatomegaly, and dysarthria[ncbi.nlm.nih.gov]

  • Chorea Gravidarum

    In addition to choreic movements, individuals with Sydenham chorea may develop muscle weakness, slurred speech (dysarthria), diminished muscle tone (hypotonia), tics, obsessions[rarediseases.org] During the examination see if you can elicit any features of ataxia (dysdiadochokinesis, intention tremor, past pointing, broad based gait), rigidity and bradykinesia.[ptpaces.wordpress.com] Dysarthria, personality changes, and emotional lability are also common.[ahcmedia.com]

  • Apraxia

    Related Problems Dysarthria Changes in muscle tone may accompany dysarthria.[csuchico.edu] […] a common disorder of the elderly in which the patient walks with a broad-based gait, taking short steps and placing the feet flat on the ground. motor apraxia impairment[medical-dictionary.thefreedictionary.com] It is a cortical problem, not a motor impulse transmission problem like dysarthria. Type Of Errors Dysarthria In dysarthria, errors are consistent and predictable.[csuchico.edu]

  • Acute Cerebellar Ataxia

    A 2-year-old boy, with the primary difficulties of nausea and vomiting, developed a staggering gait and dysarthria 10 days after varicella vaccination.[ncbi.nlm.nih.gov] The major clinical features were rapid development of gait ataxia, limb ataxia and dysarthria. None of the patients had altered sensorium.[ncbi.nlm.nih.gov] […] mildest cases of acute cerebellar ataxia represent a benign condition that is characterized by acute truncal and gait ataxia, variably with appendicular ataxia, nystagmus, dysarthria[ncbi.nlm.nih.gov]

  • Homocystinuria

    A developmentally delayed 10-year-old girl presented with symptoms of progressive ataxia, dysarthria, tremor, mental status changes, and white-matter changes on magnetic resonance[ncbi.nlm.nih.gov] Important findings are fair hair and skin, rosy cheeks, dislocated lenses, mental retardation, and flat-footed, broad-based gait.[healio.com]

  • Spinocerebellar Ataxia Type 1

    […] an autosomal dominant genetic disease in which progressive central nervous system degeneration (primarily of the cerebellum) results in the appearance of gait disorders, dysarthria[symptoma.com] There is a broad-based gait, scanning dysarthria, explosive speech, intention tremor, dysdiadochokinesia, dysmetria and abnormalities of eye movements.[patient.info] The fully developed disease included additional clinical findings such as dysarthria and dysphagia, and instrumental signs of axonal involvement of the peripheral nerves.[ncbi.nlm.nih.gov]

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