Broad Great Toe: Causes & Reasons

Possible Causes for Broad Great Toe

[…] thumbs and great toes. [ncbi.nlm.nih.gov]

Rubinstein-Taybi syndrome (RTS) is characterized by typical facies, short stature, mental retardation, broad thumbs and broad great toes. [ncbi.nlm.nih.gov]

Broad great toes in a child with Rubinstein-Taybi syndrome (RSTS). [emedicine.com]

Kleiner Holmes Syndrome

One brother had duplication-triplication of the great toes and the other had unusually broad great toes with incomplete duplication of the phalanges. [accessanesthesiology.mhmedical.com]

One presented duplication/triplication of the great toes and the other had unusually broad great toes with incomplete duplication of the phalanges. [accesspediatrics.mhmedical.com]

[…] bad unusually broad great toes with Incomplete duplication of the phalanges. [checkorphan.org]

Saethre-Chotzen Syndrome

great toes, and mild shortness of stature. [ncbi.nlm.nih.gov]

great toes, clinodactyly, and syndactyly. [ncbi.nlm.nih.gov]

Here we report on a patient with findings of acrocephaly, craniosynostosis, low frontal hairline, ptosis of eyelids, deviated nasal septum, broad great toes, moderate hallux [ncbi.nlm.nih.gov]

Familial Scaphocephaly Syndrome

Jackson-Weiss syndrome: An autosomal dominant craniosynostosis syndrome characterized by craniofacial abnormalities and abnormality of the feet: broad great toes with medial [ab-y-ss.com]

JWS is an autosomal dominant craniosynostosis syndrome characterized by craniofacial abnormalities and abnormality of the feet: broad great toes with medial deviation and [abcam.com]

His mother (III:24) has a broad great toe and partial 2,3 syndactyly of the toes. [jmg.bmj.com]

Leri Pleonosteosis

This syndrome is compared with the other acrocephalosyndactyly types and the various broad thumb and great toe syndromes. [jamanetwork.com]

Characteristic abnormalities of the hands and feet may include unusually broad and/or short thumbs and great toes (brachydactyly) that may be bent outward from the body (valgus [healthmedicinet.com]

Many infants with this disorder have abnormally short and/or broad fingers (brachydactyly), giving the hands a “spade-shaped” appearance; the toes may also be affected. [rarediseases.org]

Distal Symphalangism

SABTS is a congenital autosomal dominant disorder that includes hyperopia, a hemicylindrical nose, broad thumbs, great toes, and other minor skeletal anomalies but lacked [abcam.com]

Stapes ankylosis with broad thumb and toes (SABTS) [MIM:184460]: Congenital autosomal dominant disorder that includes hyperopia, a hemicylindrical nose, broad thumbs, great [genecards.org]

Disease description An autosomal dominant disorder characterized by hyperopia, a hemicylindrical nose, broad thumbs, great toes, and other minor skeletal anomalies but lacked [uniprot.org]

Cloverleaf Skull

The distinguishing feature of Pfeiffer syndrome compared with other causes of early skull fusion is the presence of broad thumbs and great toes. [consultant360.com]

Michael Cohen in 1993. [1] [7] Cohen divided the syndrome into three possibly overlapping types, all of which are characterized by broad thumbs, broad great toes, brachydactyly [en.wikipedia.org]

Michael Cohen classification Pfeiffer syndrome can be divided into 3 types characterized by broad thumbs, broad great toes, brachydactyly, and possibly syndactyly. [drugsdetails.com]

Pfeiffer Syndrome Type 3

great toes. [ncbi.nlm.nih.gov]

The characteristic feature that distinguishes Pfieffer syndrome from other types of syndromic craniosynostosis is the presence of the broad thumb and great toe. [chop.edu]

great toes (Figure 2 and Figure 3). [ncbi.nlm.nih.gov]

Robinow-Sorauf Syndrome

Autosomal dominant disease Synopsis flat facies thin, long, pointed nose shallow orbits hypertelorism plagiocephaly (asymmetry of orbits) strabismus broad great toes duplicated [humpath.com]

great toes with a duplication of the distal phalanx. [uniprot.org]

[…] autosomal dominant syndrome characterized by craniosynostosis, asymmetry of orbits, flat face, hypertelorism, a thin, long, and pointed nose, shallow orbits, strabismus, and broad [uniprot.org]

Jackson-Weiss Syndrome

Definition An autosomal dominant craniosynostosis syndrome characterized by craniofacial abnormalities and abnormality of the feet: broad great toes with medial deviation [uniprot.org]

great toes; and/or malformation or fusion of certain bones within the feet. [globalgenes.org]

[…] fibrous joints (cranial sutures) between certain bones of the skull (craniosynostosis); unusually flat, underdeveloped midfacial regions (midfacial hypoplasia); abnormally broad [articlesfactory.com]

Rubinstein-Taybi-Like Syndrome

[…] thumbs and great toes, characteristic facies, and intellectual disability; Broad thumbs-halluces syndrome; RSTS; Rubinstein syndromeBroad thumb-hallux syndrome; Broad thumbs [rarediseases.info.nih.gov]

Rubinstein-Taybi syndrome is a well-delineated malformation syndrome characterized by facial abnormalities, broad thumbs, broad great toes, short stature, and mental retardation [emedicine.medscape.com]

Union Méd Can 96:22–29 Google Scholar Johnson CF (1966) Broad thumbs and broad great toes with facial abnormalities and mental retardation. [link.springer.com]

Pfeiffer Syndrome

great toes. [panafrican-med-journal.com]

Severe ocular proptosis (protruding eyes) Broad thumbs and great toes Central nervous system anomalies Limited extension of elbow Type 3 Similar to type 2 without cloverleaf [nicklauschildrens.org]

Other features may include broad and deviated thumbs and great toes; brachydactyly; and syndactyly. [malacards.org]

Samson-Viljoen Syndrome

great toe macrocranium * Short chain Acyl CoA dehydrogenase deficiency * Short limb dwarf lethal Colavita Kozlowski type * Short limb dwarf lethal Mcalister Crane type * [en-academic.com]

great toe macrocranium Short chain acyl CoA dehydrogenase deficiency Short limb dwarf edema iris coloboma Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf [personalizedcause.com]

Sheehan syndrome * Shigellosis * Shingles * Shith Filkins syndrome ho Shok - Shor - Shou * Shock---- hok * Shokeir syndrome hor hort b-Short r * Short bowel syndrome * Short broad [en-academic.com]

Siegler-Brewer-Carey Syndrome

great toe macrocranium Short chain Acyl CoA dehydrogenase deficiency Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf lethal Mcalister Crane type Short limb [ssf.f15ijp.com]

Short broad great toe macrocranium[?] Short chain Acyl CoA dehydrogenase deficiency[?] Short limb dwarf lethal Colavita Kozlowski type[?] [encyclopedia.kids.net.au]

Shaver's disease Sheehan syndrome Shigellosis Shingles Shith Filkins syndrome Sho Shok - Shor - Shou Shock Shok Shokeir syndrome Shor Short b-Short r Short bowel syndrome Short broad [ssf.f15ijp.com]

Sequeiros Sack Syndrome

great toe macrocranium * Short chain Acyl CoA dehydrogenase deficiency * Short limb dwarf lethal Colavita Kozlowski type * Short limb dwarf lethal Mcalister Crane type * [en-academic.com]

great toe macrocranium Short chain acyl CoA dehydrogenase deficiency Short limb dwarf edema iris coloboma Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf [personalizedcause.com]

Sheehan syndrome * Shigellosis * Shingles * Shith Filkins syndrome ho Shok - Shor - Shou * Shock---- hok * Shokeir syndrome hor hort b-Short r * Short bowel syndrome * Short broad [en-academic.com]

Partial Monosomy 6p

Robinow syndrome also known as fetal face syndrome is a rare disorder with characteristic facial phenotype resembling fetal face with macrocephaly, low-set ears, broad great [link.springer.com]

toes, gum hypertrophy, micropenis, and rhizomelia. [link.springer.com]

Semmekrot-Haraldsson-Weemaes Syndrome

great toe macrocranium Short chain acyl CoA dehydrogenase deficiency Short limb dwarf edema iris coloboma Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf [personalizedcause.com]

Sezary syndrome Shapiro syndrome Sharma Kapoor Ramji syndrome Sharp syndrome Shaver's disease Sheehan syndrome Shigellosis Shith Filkins syndrome Short bowel syndrome Short broad [personalizedcause.com]

Short Stature - Wormian Bones - Dextrocardia Syndrome

Short broad great toe macrocranium[?] Short chain Acyl CoA dehydrogenase deficiency[?] Short limb dwarf lethal Colavita Kozlowski type[?] [encyclopedia.kids.net.au]

Cerebro-Facio-Thoracic Dysplasia

occasionally bifid, cardiac defects in 25%, broad great toes in 100%, ear infections are common Sleep problems possibly due to sleep apnea, feeding difficulties are common [en.wikibooks.org]

[…] antimongoloid eye slant, hypertelorism, long eyelashes, milt ptosis, prominent and/or beaked nose with or without nasal septum extending below alae nasi (100%), thumbs are broad [en.wikibooks.org]

Thai Symphalangism Syndrome

SABTS is a congenital autosomal dominant disorder that includes hyperopia, a hemicylindrical nose, broad thumbs, great toes, and other minor skeletal anomalies but lacked [abcam.com]

Defects in NOG are a cause of stapes ankylosis with broad thumb and toes (SABTS) [MIM:184460]; also known as Teunissen-Cremers syndrome. [abcam.com]

Craniosytosis Mental Retardation Syndrome of Lin and Gettig

JWS is an autosomal dominant craniosynostosis syndrome characterized by craniofacial abnormalities and abnormality of the feet: broad great toes with medial deviation and [abcam.com]

Some affected individuals may have syndactyly involving the fifth toes and the great toes; unusually broad, deviating great toes (hallux varus); or other bony abnormalities [rarediseases.org]

This is a multisystem disorder that is characterized by growth retardation, mental retardation, craniofacial dysmorphism, abnormally broad thumbs and great toes Fusions between [brainscape.com]

FG Syndrome Type 5

[…] thumbs and great toes, a large head compared to body size (relative macrocephaly), and abnormalities of the corpus callosum. [rarediseases.info.nih.gov]

[…] thumbs and great toes Neurologic Severe hypotonia Others Imperforate anus may be present Undescended testes (cryptorchidism) Laboratory Findings MRI Partial or complete loss [wikidoc.org]

People with FG syndrome frequently have intellectual disability ranging from mild to severe, hypotonia, constipation and/or anal anomalies, a distinctive facial appearance, broad [rarediseases.info.nih.gov]

Seckel-Like Syndrome Type Majoor-Krakauer

great toe macrocranium Short chain acyl CoA dehydrogenase deficiency Short limb dwarf edema iris coloboma Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf [personalizedcause.com]

Antinolo-Nieto-Borrego Syndrome

Short broad great toe macrocranium[?] Short chain Acyl CoA dehydrogenase deficiency[?] Short limb dwarf lethal Colavita Kozlowski type[?] [encyclopedia.kids.net.au]

great toe macrocranium Short chain Acyl CoA dehydrogenase deficiency Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf lethal Mcalister Crane type Short limb [wikidoc.org]

Shaver's Disease Sheehan syndrome Shigellosis Shingles Shith Filkins syndrome Sho Shok - Shor - Shou Shock Shok Shokeir syndrome Shor Short b-Short r Short bowel syndrome Short broad [wikidoc.org]

Selig-Benacerraf-Greene Syndrome

great toe macrocranium * Short chain Acyl CoA dehydrogenase deficiency * Short limb dwarf lethal Colavita Kozlowski type * Short limb dwarf lethal Mcalister Crane type * [en-academic.com]

great toe macrocranium Short chain acyl CoA dehydrogenase deficiency Short limb dwarf edema iris coloboma Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf [personalizedcause.com]

Sheehan syndrome * Shigellosis * Shingles * Shith Filkins syndrome ho Shok - Shor - Shou * Shock---- hok * Shokeir syndrome hor hort b-Short r * Short bowel syndrome * Short broad [en-academic.com]

FLNB-Related Disorder

She presented with prominent forehead, depressed nasal bridge, telecanthus (a), broad fingertips, spatulate thumbs (b and c), bilateral knee dislocation (d), broad great toes [ncbi.nlm.nih.gov]

Joint laxity was noted in both knee joints (Fig. 5d), bilateral club feet and broad great toes were also noted (Fig. 5e). Bilateral elbow and wrist joints were normal. [ncbi.nlm.nih.gov]

She had spatulate thumbs, broad fingertips (Fig. 5b and c), and joint laxity. [ncbi.nlm.nih.gov]

Syndactyly - Polydactyly - Ear Lobe Syndrome

Short broad great toe macrocranium[?] Short chain Acyl CoA dehydrogenase deficiency[?] Short limb dwarf lethal Colavita Kozlowski type[?] [encyclopedia.kids.net.au]

Craniosynostosis with Ocular Abnormalities and Hallucal Defects

great toes with a duplication of the distal phalanx. [nectarmutation.org]

The first metatarsals and proximal phalanges of the great toes are generally broad. [disorders.eyes.arizona.edu]

great toes and broad thumbs. [entokey.com]

Seres-Santamaria Arimany Muniz Syndrome

great toe macrocranium * Short chain Acyl CoA dehydrogenase deficiency * Short limb dwarf lethal Colavita Kozlowski type * Short limb dwarf lethal Mcalister Crane type * [en-academic.com]

great toe macrocranium Short chain acyl CoA dehydrogenase deficiency Short limb dwarf edema iris coloboma Short limb dwarf lethal Colavita Kozlowski type Short limb dwarf [personalizedcause.com]

Sheehan syndrome * Shigellosis * Shingles * Shith Filkins syndrome ho Shok - Shor - Shou * Shock---- hok * Shokeir syndrome hor hort b-Short r * Short bowel syndrome * Short broad [en-academic.com]

Craniosynostosis Type 3

great toes with a duplication of the distal phalanx. [uniprot.org]

[…] thumbs or great toes -Midface hypoplasia - BEAK nose -Mild cutaneous syndactyly -Class III malocclusion -Ocular hypertelorism -Shallow orbits / exorbitism -High risk for [quizlet.com]

Type 1 corresponds to the classic phenotype characterized by brachycephaly, broad thumb and great toe, variable degrees of syndactyly, and normal intelligence. [rrnursingschool.biz]