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120 Possible Causes for Broad Nasal Bridge, Brushfield Spot

  • Down Syndrome

    bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21 — called also trisomy 21 First Known Use of Down syndrome[merriam-webster.com] Brushfield's spots: Speckled iris. Little white spots that slightly elevated on the surface of the iris arranged in a ring concentric with the pupil.[medterms.com] Results: Ocular findings included nystagmus (29.2%), esotropia (26.1%), epiphora (21.5%), Brushfield spots (16.9%), lens opacities (12.3%), abnormalities of the retinal vessels[dx.doi.org]

  • Zellweger Syndrome

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] We did not observe any Brushfield spots, any renal and brain cysts, or adrenal insufficiency.[ncbi.nlm.nih.gov] Clinical Features [ edit ] Craniofacial Features Flat occiput and face Anteverted nares Epicanthal folds Brushfield spots High forehead Large fontanels Shallow orbits Ocular[en.wikibooks.org]

  • Smith-Magenis Syndrome

    The common clinical findings were: speech delay with behavioural problems associated with broad flat midface, brachycephaly, broad nasal bridge and brachydactyly.[ncbi.nlm.nih.gov] Both conditions share brachycephaly, upward slanting palpebral fissures, a short and broad nose, a round face with midface flattening, iris hamartomas (Brushfield spots in[jmg.bmj.com] The main clinical features consist of a broad flat midface with brachycefaly, broad nasal bridge, brachydactily, speech delay, hoarse deep voice and peripheral neuropathy.[ncbi.nlm.nih.gov]

  • Baraitser-Winter Syndrome 1

    Her facial anomalies included high arched eyebrows, hypertelorism, downslanted palpebral fissures, a broad nasal bridge, a broad nasal tip and columella, anteverted nostrils[ncbi.nlm.nih.gov] spots, upslanting palpebral fissures, epicanthal folds Most cases not inherited Trisomy 21 (most cases), translocation, mosaic #190685 DOYNE HONEYCOMB DYSTROPHY (MALATTIA[eyewiki.aao.org] Facial dysmorphism included high arched eyebrows, proptosis, hypertelorism, downslanted palpebral fissures, broad nasal bridge, broad nasal tip and columella, anteverted nostrils[ncbi.nlm.nih.gov]

  • Acro-Fronto-Facio-Nasal Dysostosis

    The three sibs suffered from marked hypertelorism, downslanting palpebral fissures, ptosis of eyelids, broad nasal bridge and tip with midline groove, dysmorphic pinna, variable[cags.org.ae] spots Brachydactyly Anonychia Cerebral cortical atrophy Micromelia ... ...[familydiagnosis.com] […] mouth Large mouth [ more ] 0000154 Wide nasal bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal[rarediseases.info.nih.gov]

  • Hypertelorism

    Clinical description Craniofacial manifestations include wide anterior fontanel, flat occiput, hypertelorism, ptosis, proptosis, broad nasal bridge and nasal tip, long philtrum[orpha.net] Down21 - non-disjunction causing trisomy 21; or Robertsonian translocation (14;21)Epicanthic folds; flat nasal bridge; protruding tongue; Brushfield spots; increased space[dontforgetthebubbles.com] […] eyebrows, long palpebral fissures, ptosis, high and broad nasal bridge, short nose, low-set ears, natal teeth, thin upper lip and a grooved chin, as well as limb (i.e. fifth-finger[orpha.net]

  • Wolf-Hirschhorn Syndrome

    The "Greek warrior helmet appearance" is the most characteristic feature and refers to the facial view with prominent glabella, high arched eyebrow, broad nasal bridge and[ncbi.nlm.nih.gov] spots Males with Down syndrome are generally infertile .[pathophys.org] The facial phenotype is characterized by hypertelorism, protruding eyes, prominent glabella, broad nasal bridge and short philtrum.[ncbi.nlm.nih.gov]

  • Lymphedema Hypoparathyroidism Syndrome

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] The pupils may have light smudgy opaque Brushfield spots.[hawaii.edu] nasal bridge Skin Nails Hair Hair: hypertrichosis (face and forehead) Growth Height: short stature Skin Nails Hair Skin: lymphedema Cardiovascular Heart: mitral valve prolapse[malacards.org]

  • Oculopalatoskeletal Syndrome

    , faint upper lid crease, a broad nasal bridge and an expressionless face [Figure 1].[ijo.in] spots Fraser’s syndrome (219000) Cryptophthalmos, malformed lacrimal ducts, hypertelorism, blindness Glucose transport defect (606777) Abnormal paroxysmal eye movements;[clinicalgate.com] […] to view She also had a surgically repaired cleft lip and palate with minimal scarring, mandibular hypoplasia, micrognathia, high arched brows, flattened superior orbital bridge[ijo.in]

  • Rieger Syndrome

    Images of patient 1 with Axenfeld-Rieger syndrome. ( A ) Facial photograph showing maxillary hypoplasia, thin upper lip, and broad nasal bridge. ( B ) Left eye with corectopia[iovs.arvojournals.org] Ocular signs include epicanthus, blepharoconjunctivitis, cataract, keratoconus, nystagmus and iris spots (Brushfield's).[medical-dictionary.thefreedictionary.com] The patient had obvious maxillary hypoplasia, broad nasal bridge, telecanthus, microdontia and hypodontia. Only 23 adult teeth had erupted [Figure 1a ].[casesjournal.biomedcentral.com]

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