Create issue ticket

25 Possible Causes for Broad Nasal Bridge, Leukemia, Wide Space Between the First and Second Toe

  • Down Syndrome

    bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21 — called also trisomy 21 First Known Use of Down syndrome[merriam-webster.com] (AMKL) and 20 times more likely to develop acute lymphoblastic leukemia (ALL) than typical children.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Dubowitz Syndrome

    nasal bridge, dysplastic auricles, and retrognathia, is presented.[ncbi.nlm.nih.gov] There is the suggestion of an association with leukemia, lymphoma, and neuroblastoma. Inheritance appears clearly autosomal recessive.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Ring Chromosome 10

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] KEY WORDS: Leukemia, myeloid, acute; Leukemia; Obesity; Chromosome aberrations; Cytogenetic analysis INTRODUCTION Acute myeloid leukemia (AML) is a heterogeneous group of[scielo.br] MalaCards based summary : Ring Chromosome 10, also known as ring chromosome 10 syndrome , is related to hirschsprung disease 2 and acute promyelocytic leukemia .[malacards.org]

  • Craniofrontonasal Dysplasia

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] We integrated the following cancer types: • Acute Myeloid Leukemia (TCGA, NEJM 2013) • Bladder Urothelial Carcinoma (TCGA, Nature 2014) • Breast Invasive Carcinoma (TCGA,[phosphosite.org] […] and broad nasal bridge.[mjdrdypu.org]

  • Atelosteogenesis Type 2

    Note dysplasia, scaphocephalic macrocephaly, coarse facial features, depressed nasal bridge, broad nasal tip, thick lips, short neck, protuberant abdomen, inguinal hernia,[thehealthscience.com] […] with maturation Acute myeloblastic leukemia without maturation Acute myelomonocytic leukemia Acute promyelocytic leukemia Aicardi-Goutières syndrome Alternating hemiplegia[csbg.cnb.csic.es] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Weaver Syndrome

    nasal bridge, accentuated philtrum, micrognathia and large ears, and unique behavior characteristics with some social withdrawal.[ncbi.nlm.nih.gov] Patients with overgrowth syndromes have an increased frequency of tumors; the risk in Sotos syndrome patients has been estimated to be about 2-3%, with leukemia and lymphoma[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Short Stature due to Endocrine Disorder

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] , Burstein S, Schriock EA, Lustig R, Danish RK, Evans WE, Hudson MM, Pui CH: Outcomes of growth hormone replacement therapy in survivors of childhood acute lymphoblastic leukemia[karger.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Baraitser Syndrome

    nasal bridge, and epicanthic folds.[pediatricneurosciences.com] Quinlan Nature Genetics (2019) Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia A-K Eisfeld , J Kohlschmidt[nature.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Kleiner Holmes Syndrome

    bridge; Choanal stenosis or atresia; Strabismus; Narrow palate; Cleft palate; Bifid uvula; Malocclusion; Delayed dental eruption; Ventricular septal defect; Overriding aorta[panelapp.genomicsengland.co.uk] Acadian variety Usher syn Page 179 and 180: Acitretin embryofetopathy Acitretin Page 181 and 182: Acromegaly Congenital optic atrophy Page 183 and 184: Acute myeloblastic leukemia[yumpu.com] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    […] flat nasal bridge, malformed ears, and short neck.[genome.jp] Leukemia L1210 Leukemia L5178 Leukemia P388 Leukemia, Basophilic, Acute Leukemia, B-Cell Leukemia, B-Cell, Acute Leukemia, B-Cell, Chronic Leukemia, CALLA-Positive Leukemia[medgene.med.harvard.edu] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

Similar symptoms